Volume 43 Issue 2
Mar.  2022
Turn off MathJax
Article Contents
Yunyan CHEN, Jinfeng CAI, Xinxin CHEN, Rongfang HUANG, Long LI, Dejiang ZHOU, Yuansong YU. The Correlation between AMH Levels in Serum and Follicular Fluid and the Number of Retrieved Oocytes During COH[J]. Journal of Kunming Medical University, 2022, 43(2): 122-127. doi: 10.12259/j.issn.2095-610X.S20220204
Citation: Yunyan CHEN, Jinfeng CAI, Xinxin CHEN, Rongfang HUANG, Long LI, Dejiang ZHOU, Yuansong YU. The Correlation between AMH Levels in Serum and Follicular Fluid and the Number of Retrieved Oocytes During COH[J]. Journal of Kunming Medical University, 2022, 43(2): 122-127. doi: 10.12259/j.issn.2095-610X.S20220204

The Correlation between AMH Levels in Serum and Follicular Fluid and the Number of Retrieved Oocytes During COH

doi: 10.12259/j.issn.2095-610X.S20220204
  • Received Date: 2021-12-17
    Available Online: 2022-02-24
  • Publish Date: 2022-03-04
  •   Objective  To study the dynamic changes of serum AMH during different periods of treatment in patients who received the treatment of controlled ovarian hyperstimulation (COH) and to observe the correlation between AMH level in large and medium follicular fluid and the number of retrieved oocytes.   Methods  Serum AMH levels were measured on days 2-4 of natural menstrual cycle of baseline (BL), day 6 of follicular stimulation (S6) and day trigger. The AMH levels in the fluid of large and medium follicles were detected. The dynamic changes of serum AMH and its relationship with the number of retrieved oocytes were analyzed. The relationship between the level of AMH and the number of retrieved oocytes was compared between large and medium follicular fluid.   Results  (1) There was a positive correlation between serum AMH and the number of retrieved oocytes. There was a significant difference in serum AMH between BL and trigger, S6 and trigger (P < 0.05); (2) The value of AMH in large follicular fluid was positively correlated with the number of retrieved oocytes, and there was significant difference between large and medium follicular fluid (P < 0.05); (3) The value of AMH increased slowly from BL to S6, and the more the number of retrieved eggs, the more obvious the increase; The AMH value decreased rapidly from S6 to trigger day, and the more oocytes were retrieved, the more obvious the decrease was.   Conclusion  Serum AMH fluctuates during COH, and dynamic monitoring of AMH can predict the number of retrieved oocytes; There may be some guiding significance for the adjustment of Gn.
  • loading
  • [1]
    邹宝玉. 抗苗勒氏管激素(AMH)预测卵巢储备功能及反应性的研究[J]. 中国优生与遗传杂志,2018,26(08):110-125.
    [2]
    王含必,邓成艳. 抗苗勒管激素的生理及在临床应用中的新进展[J]. 生殖医学杂志,2021,30(02):257-261.
    [3]
    Sopa N,Larsen E C,Westring H H,et al. An AMH-based FSH dosing algorithm for OHSS risk reduction in first cycle antagonist protocol for IVF/ICSI[J]. Eur J Obstet Gynecol Reprod Biol,2019,237:42-47.
    [4]
    Li H,Ko J,Lee V,et al. Comparison of antral follicle count and serum anti Mullerian hormone level for determination of gonadotropin dosing in in-vitro fertilization:randomized trial[J]. Ultrasound Obstet Gynecol,2020,55(3):303-309. doi: 10.1002/uog.20402
    [5]
    王冬雪,吴小华. 超促排卵过程中抗苗勒管激素动态变化及其与临床结局的相关性[J]. 中华生殖与避孕杂志,2017,37(2):111-116.
    [6]
    莫辉,王华为,王港,等. 抗苗勒管激素水平与卵巢反应性的相关性分析[J]. 实用妇产科杂志,2020,36(1):62-66.
    [7]
    何艺磊,李蓉,乔杰. 抗苗勒管激素在性腺相关疾病中的应用[J]. 实用妇产科杂志,2017,33(11):822-826.
    [8]
    邵静宜,马艳萍,李云秀. 抗苗勒氏管激素与生殖[J]. 中国优生与遗传杂志,2012,20(5):13-15.
    [9]
    Peigne M,Decanter C. Serum AMH level as a marker of acute and long-term effects of chemotherapy on the ovarian follicular content:a systematic review[J]. Reprod Biol Endocrinol,2014,12:26.
    [10]
    Fleming R,Kelsey T W,Anderson R A,et al. Interpreting human follicular recruitment and antimullerian hormone concentrations throughout life[J]. Fertil Steril,2012,98(5):1097-1102. doi: 10.1016/j.fertnstert.2012.07.1114
    [11]
    陈雅,叶碧绿,郑九嘉,等. 血清及卵泡液抗苗勒管激素在多囊卵巢综合征患者体外受精促排卵治疗中的价值[J]. 中国临床药理学与治疗学,2015,20(12):1405-1411.
    [12]
    王起来,马寅芙,付建华,等. 血清和卵泡液抗苗勒管激素在IVF-ET中的检测价值[J]. 中国实验诊断学,2017,21(12):2062-2064. doi: 10.3969/j.issn.1007-4287.2017.12.006
    [13]
    徐鑫. 血清抗苗勒管激素对高龄女性体外受精—胚胎移植临床妊娠的预测价值[D]. 长春: 吉林大学硕士学位论文, 2018.
    [14]
    Jamil Z,Fatima S S,Ahmed K,et al. Anti-Mullerian Hormone:Above and Beyond Conventional Ovarian Reserve Markers[J]. Dis Markers,2016,16:5246217.
    [15]
    Mashiach R,Amit A,Hasson J,et al. Follicular fluid levels of anti-Mullerian hormone as a predictor of oocyte maturation,fertilization rate,and embryonic development in patients with polycystic ovary syndrome[J]. Fertil Steril,2010,93(7):2299-2302. doi: 10.1016/j.fertnstert.2009.01.125
    [16]
    高变变,马晓龙,杨玲玲,等. 血清及卵泡液AMH水平与IVF-ET妊娠结局关系的探讨[J]. 宁夏医科大学学报,2020,42(7):659-663.
    [17]
    Tramisak M T,Panic H L,Cavlovic K,et al. Follicular fluid anti-Mullerian hormone:a predictive marker of fertilization capacity of MII oocytes[J]. Arch Gynecol Obstet,2015,291(3):681-687. doi: 10.1007/s00404-014-3460-9
  • Relative Articles

    [1] Xingfei DAI, Qitang LI, Rongshuang YAN, Qingdong ZHANG, Cheng PAN, Derui FEI, Yujian MA, Shixin XU, Ying ZHANG. Molecular Analysis on the Molecular Mechanism of Lung Development in the Piglet Model of Early Onset Scoliosis Complicated with Thoracic Insufficiency Syndrome. Journal of Kunming Medical University, 2024, 45(5): 49-59.  doi: 10.12259/j.issn.2095-610X.S20240508
    [2] Bo PENG, Gang SU, Rong QIN, Rong WEN, Wei YIN. Observation of Achieving Controlled Low Central Venous Pressure with Goal-directed Fluid Therapy Combined with Milrinone in Laparoscopic Hepatic Lobectomy. Journal of Kunming Medical University, 2024, 45(9): 116-121.  doi: 10.12259/j.issn.2095-610X.S20240918
    [3] Zexing YANG, Ya WEN, Cunmei SU, Huawei WANG, Meng RAO, Yuhang ZHENG, Limei HE. Comparison the Clinical Outcomes of Progestin-Primed Ovarian Stimulation during Follicular Period and Mild-stimulation in Patients with Diminished Ovarian Reserve. Journal of Kunming Medical University, 2022, 43(12): 53-57.  doi: 10.12259/j.issn.2095-610X.S20221211
    [4] Li-yuan WU, Su-yi LUO, Yong-jie GU, Qi-peng WANG, Jia-hao XU. Antagonistic Effect of Total Flavonoids of Panax notoginseng on Osteoporosis Induced by Glucocorticoid. Journal of Kunming Medical University, 2020, 41(11): 25-29.  doi: 10.12259/j.issn.2095-610X.S20201117
    [5] Zhang Zun Yue , Li Ping , Tang Li , Wang Kun Hua , Long Yan Xi , Wang Hua Wei . . Journal of Kunming Medical University, 2019, 40(01): 118-122.
    [6] Lu Li Juan . Comparison of A Variety of Methods for the Diagnosis of Uterine Dysplasia. Journal of Kunming Medical University,
    [7] Chen Zong Ning . The Impact of Autocapture Function on the Service life of Cardiac Pacemaker. Journal of Kunming Medical University,
    [8] Liu Jing . Effect of Early Intervention in Neurodevelopment on Motor and Cognitive Development of High Risk Premature Infants. Journal of Kunming Medical University,
    [9] Li Yan . . Journal of Kunming Medical University,
    [10] Tian Ming . . Journal of Kunming Medical University,
    [11] Ding Hai Yan . . Journal of Kunming Medical University,
    [12] Yao Yong Liang . . Journal of Kunming Medical University,
    [13] Cheng Bo . . Journal of Kunming Medical University,
    [14] Li Xu Hua . . Journal of Kunming Medical University,
    [15] Ren Chao Feng . . Journal of Kunming Medical University,
    [16] He Jin . . Journal of Kunming Medical University,
    [17] Fu Min . . Journal of Kunming Medical University,
    [18] Wen Yong . . Journal of Kunming Medical University,
    [19] . The Application of Damage Control Operation in Ultrasound interventional treatment of Bile Duct Injury. Journal of Kunming Medical University,
    [20] Cao Yue Ling . . Journal of Kunming Medical University,
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(1)  / Tables(8)

    Article Metrics

    Article views (2454) PDF downloads(12) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return