The Correlation between AMH Levels in Serum and Follicular Fluid and the Number of Retrieved Oocytes During COH

Yunyan CHEN; Jinfeng CAI; Xinxin CHEN; Rongfang HUANG; Long LI; Dejiang ZHOU; Yuansong YU

doi:10.12259/j.issn.2095-610X.S20220204

Volume 43 Issue 2

Mar. 2022

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Yunyan CHEN, Jinfeng CAI, Xinxin CHEN, Rongfang HUANG, Long LI, Dejiang ZHOU, Yuansong YU. The Correlation between AMH Levels in Serum and Follicular Fluid and the Number of Retrieved Oocytes During COH[J]. Journal of Kunming Medical University, 2022, 43(2): 122-127. doi: 10.12259/j.issn.2095-610X.S20220204

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The Correlation between AMH Levels in Serum and Follicular Fluid and the Number of Retrieved Oocytes During COH

doi: 10.12259/j.issn.2095-610X.S20220204

Dept. of Reproductive Health and Infertility，Kunming Maternal and Child Health Hospital，Kunming Yunnan 650031，China

Received Date: 2021-12-17
Available Online: 2022-02-24
Publish Date: 2022-03-04

Abstract

Abstract

Objective To study the dynamic changes of serum AMH during different periods of treatment in patients who received the treatment of controlled ovarian hyperstimulation （COH） and to observe the correlation between AMH level in large and medium follicular fluid and the number of retrieved oocytes. Methods Serum AMH levels were measured on days 2-4 of natural menstrual cycle of baseline （BL）, day 6 of follicular stimulation （S6） and day trigger. The AMH levels in the fluid of large and medium follicles were detected. The dynamic changes of serum AMH and its relationship with the number of retrieved oocytes were analyzed. The relationship between the level of AMH and the number of retrieved oocytes was compared between large and medium follicular fluid. Results （1） There was a positive correlation between serum AMH and the number of retrieved oocytes. There was a significant difference in serum AMH between BL and trigger, S6 and trigger （P < 0.05）; （2） The value of AMH in large follicular fluid was positively correlated with the number of retrieved oocytes, and there was significant difference between large and medium follicular fluid （P < 0.05）; （3） The value of AMH increased slowly from BL to S6, and the more the number of retrieved eggs, the more obvious the increase; The AMH value decreased rapidly from S6 to trigger day, and the more oocytes were retrieved, the more obvious the decrease was. Conclusion Serum AMH fluctuates during COH, and dynamic monitoring of AMH can predict the number of retrieved oocytes; There may be some guiding significance for the adjustment of Gn.
- Anti-mullerian hormone,
- Controls ovulation hyperstimulation,
- Number of eggs retrieved,
- Follicular development

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References

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