Optimization of Heating Reflux Extraction Process for Qingyangshengenin

Jiacan YAO; Haiyin WANG; Xiaoxuan XU; Yiting LUO; Xianguang HU; Leilei LIANG

doi:10.12259/j.issn.2095-610X.S20220401

Volume 43 Issue 4

Apr. 2022

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Jiacan YAO, Haiyin WANG, Xiaoxuan XU, Yiting LUO, Xianguang HU, Leilei LIANG. Optimization of Heating Reflux Extraction Process for Qingyangshengenin[J]. Journal of Kunming Medical University, 2022, 43(4): 1-5. doi: 10.12259/j.issn.2095-610X.S20220401

Citation:

Jiacan YAO, Haiyin WANG, Xiaoxuan XU, Yiting LUO, Xianguang HU, Leilei LIANG. Optimization of Heating Reflux Extraction Process for Qingyangshengenin[J]. Journal of Kunming Medical University, 2022, 43(4): 1-5. doi: 10.12259/j.issn.2095-610X.S20220401

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Optimization of Heating Reflux Extraction Process for Qingyangshengenin

doi: 10.12259/j.issn.2095-610X.S20220401

1.
School of Pharmaceutical Sciences and Yunnan Key Laboratory of Pharmacology for Natural Products
2.
School of Basic Medicine，Kunming Medical University， Kunming Yunnan 650500，China

Received Date: 2022-01-01
Accepted Date: 2022-02-28

Available Online: 2022-03-15

Publish Date: 2022-04-25

Abstract

Abstract

Objective To investigate the optimum extraction technology of Qingyangshengenin from the medicinal plant Cynanchum otophyllum Schnei. Methods The reflux method is used to extract and HPLC method is used to detect Qingyangshengenin. On the basis of single factor experimental, orthogonal design method is selected to explore the conditions of ethanol volume fraction, solid-liquid ratio and extraction time on the extraction of Qingyangshengenin. Results The optimal extraction conditions were as follows: ethanol volume fraction 70%, solid-liquid ratio 1∶15（g/mL）, extraction time 2 h, and the extraction rate was up to 0.3090%. Conclusion The optimized heating reflux extraction process was effective, stable and environment-friendly, which provided a foundation for further studies on pharmacological activity and structural modification of Qingyangshengenin.
- Cynanchum otophyllum Schnei,
- Qingyangshengenin,
- Reflux extraction,
- 0rthogonal design.

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References(16)

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