Vitamin D  Status of 2563 Subjects in Kunming

Ying ZHAO; Yandan SU; Ruizhu TANG; Yong DUAN; Wenping SHAO

doi:10.12259/j.issn.2095-610X.S20220405

Volume 43 Issue 4

Apr. 2022

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Ying ZHAO, Yandan SU, Ruizhu TANG, Yong DUAN, Wenping SHAO. Vitamin D Status of 2563 Subjects in Kunming[J]. Journal of Kunming Medical University, 2022, 43(4): 19-25. doi: 10.12259/j.issn.2095-610X.S20220405

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Ying ZHAO, Yandan SU, Ruizhu TANG, Yong DUAN, Wenping SHAO. Vitamin D Status of 2563 Subjects in Kunming[J]. Journal of Kunming Medical University, 2022, 43(4): 19-25. doi: 10.12259/j.issn.2095-610X.S20220405

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Vitamin D Status of 2563 Subjects in Kunming

doi: 10.12259/j.issn.2095-610X.S20220405

Dept.of Clinical Laboratory，The 1st Affiliated Hospital of Kunming Medical University/Yunnan Province Clinical Research Center for Laboratory Medicine/Yunnan Key Laboratory of Laboratory Medicine，Kunming Yunnan 650032， China

Received Date: 2022-02-13
Available Online: 2022-03-23
Publish Date: 2022-04-25

Abstract

Abstract

Objective By measuring the blood level of 25-hydroxyvitamin D [25（OH）D] in healthy population, taking Kunming area as an example, the present vitamin D level and its influencing factors in Yunnan Plateau were analyzed and discussed. Methods Serum samples were collected from cases who underwent health examination in the First Affiliated Hospital of Kunming Medical University. Subjects were grouped by sex, season and age. Serum 25（OH） D level was detected by electrochemical luminescence immunoassay. Results The average 25（OH）D level of 2563 subjects was（62.79±23.33）nmol/mL. The normal, insuffcient and deficient rates of vitamin D were 26.06%, 42.84% and 31.10%, respectively. The results showed that gender, season and age all affected serum 25（OH）D. The vitamin D level in women was significantly lower than that in men （P < 0.05）, and the vitamin D deficiency in women was also significantly higher than that in men. There was statistical significance in 25（OH） D levels in different seasons（P < 0.05）. The vitamin D level in autumn was significantly higher than that in other three seasons （P < 0.05）. The difference of 25（OH）D level among age groups was statistically significant （P < 0.05）. Conclusion Different levels of vitamin D deficiency existed in Yunnan Plateau area, which was related to gender, season and age. 25（OH） D test can provide an important reference for clinical evaluation, diagnosis and treatment of metabolic diseases caused by vitamin D deficiency.
- Serum 25-hydroxyvitamin D,
- Kunming,
- Gender,
- Season,
- Age

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References(26)

References

[1]	Holick M F. The vitamin D deficiency pandemic:Approaches for diagnosis,treatment and prevention[J]. Reviews in endocrine & Metabolic Disorders,2017,18(2):153-165.
[2]	Holick M F. Sunlight and vitamin D for bone health and prevention of autoimmune diseases,cancers,and cardiovascular disease[J]. The American Journal of Clinical Nutrition,2004,80(6 Suppl):1678-1688.
[3]	Gulseth H L,Wium C,Birkeland K I. Vitamin D and insulin action and secretion –an overview of current understanding and future perspectives[J]. European Endocrinology,2010,6(2):13. doi: 10.17925/EE.2010.06.02.13
[4]	Jorde R,Grimnes G. Vitamin D and health:The need for more randomized controlled trials[J]. The Journal of Steroid Biochemistry and Molecular Biology,2015,148:269-274. doi: 10.1016/j.jsbmb.2015.01.021
[5]	包金晶,戴芳芳. 3326例南京地区人群维生素D水平与季节关系调查[J]. 中国骨质疏松杂志,2019,25(2):4.
[6]	廖祥鹏,张增利,张红红,等. 维生素D与成年人骨骼健康应用指南(2014年标准版)[J]. 中国骨质疏松杂志,2014,20(9):1011-1030. doi: 10.3969/j.issn.1006-7108.2014.09.002
[7]	Mithal A,Wahl D A,Bonjour J P,et al. Global vitamin D status and determinants of hypovitaminosis D[J]. Osteoporosis International,2009,20(11):1807-1820. doi: 10.1007/s00198-009-0954-6
[8]	Tsiaras W G,Weinstock M A. Factors influencing vitamin D status[J]. Acta Derm Venereol,2011,91(2):115-124. doi: 10.2340/00015555-0980
[9]	Hypp Nen E,Power C. Hypovitaminosis D in british adults at age 45 y:Nationwide cohort study of dietary and lifestyle predictors[J]. The American Journal of Clinical Nutrition,2007,85(3):860-868. doi: 10.1093/ajcn/85.3.860
[10]	Hirschler V,Maccallini G,Molinari C,et al. Low vitamin D concentrations among indigenous argentinean children living at high altitudes[J]. Pediatric Diabetes,2013,14(3):203-210.
[11]	高倩,刘儒曦,葛天添,等. 我国地理气候因素与人群血清25-羟维生素D水平的关系初步研究[J]. 环境与健康杂志,2013,30(7):617-620.
[12]	Kelishadi R,Moeini R,Poursafa P,et al. Independent association between air pollutants and vitamin D deficiency in young children in Isfahan,Iran[J]. Paediatrics and International Child Health,2014,34(1):50-55. doi: 10.1179/2046905513Y.0000000080
[13]	Panjiyar R P,Dayal D,Attri S V,et al. Sustained serum 25-hydroxyvitamin D concentrations for one year with cholecalciferol supplementation improves glycaemic control and slows the decline of residual β cell function in children with type 1 diabetes[J]. Pediatric Endocrinology, Diabetes, and Metabolism,2018,2018(3):111-117.
[14]	Marwaha R K,Garg M K,Sethuraman G. Impact of three different daily doses of vitamin D3 supplementation in healthy schoolchildren and adolescents from North India:A single-blind prospective randomised clinical trial[J]. Randomized Controlled Trial,2019,121(5):538-548.
[15]	何清华,周晓梅,陈德才,等. 高原建设者维生素D水平的影响因素调查研究[J]. 四川医学,2016,37(7):721-725.
[16]	王佳伟. 膳食、营养素摄入对不同海拔居民血液氧化应激水平的影响 [D]. 广州: 中山大学硕士学位论文, 2009.
[17]	Ning Z,Song S,Miao L,et al. High prevalence of vitamin D deficiency in urban health checkup population[J]. Clin Nutr,2016,35(4):859-863.
[18]	陈京蓉,赵怡楠,张洁,等. 重庆市部分区县6~17岁儿童青少年维生素D营养状况及相关因素分析[J]. 现代预防医学,2021,48(1):50-54.
[19]	周波,王晓红,徐超,等. 沈阳市区中老年人维生素D缺乏状况[J]. 中国老年学杂志,2010,30(21):3150-3151. doi: 10.3969/j.issn.1005-9202.2010.21.051
[20]	宋成伟,刘艳萍,邵延坤. 长春市中老年人维生素D水平调查及其影响因素研究[J]. 中国实验诊断学,2014,18(8):1344-1345.
[21]	仓桢,王宁荐,李琴,等. 华东地区自然人群血清维生素D水平调查[J]. 中华内分泌代谢杂志,2017,33(9):726-729. doi: 10.3760/cma.j.issn.1000-6699.2017.09.003
[22]	朱汉民,程群,甘洁民,等. 上海地区人群维生素D状态研究[J]. 中华骨质疏松和骨矿盐疾病杂志,2010,3(3):157-163. doi: 10.3969/j.issn.1674-2591.2010.03.002
[23]	蒋黎纯,杨清萍,王宏智. 嘉兴地区人群维生素D水平及其影响因素[J]. 中华骨质疏松和骨矿盐疾病杂志,2017,10(4):375-377. doi: 10.3969/j.issn.1674-2591.2017.04.011
[24]	韦丽娅,陈庆瑜,甘小玲. 广州地区人群血清25-羟维生素D水平的季节性变化[J]. 中国全科医学,2014,17(35):4217-4219.
[25]	Vieth R,Ladar Y,Walfish P G. Age-related changes in the 25-hydroxyvitamin D versus parathyroid hormone relationship suggest a different reason why older adults require more vitamin D[J]. The Journal of Clinical Endocrinology and Metabolism,2003,88(1):185-191. doi: 10.1210/jc.2002-021064
[26]	Hagenau T,Vest R,Gissel T N,et al. Global vitamin D levels in relation to age,gender,skin pigmentation and latitude:An ecologic meta-regression analysis[J]. Osteoporosis International,2009,20(1):133-140. doi: 10.1007/s00198-008-0626-y

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