Volume 43 Issue 5
May  2022
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Article Navigation >  Journal of Kunming Medical University  > 2022  >  43(5): 123-126
Xiao-yun WANG, Qiao-yun WANG, Ming-hua GU, Yu DING, Yu-wen GUANG, Ji-lan ZHANG. Mechanism of miR-373 on Behaviors of Depression-mice via P2X7R[J]. Journal of Kunming Medical University, 2021, 42(10): 29-37. doi: 10.12259/j.issn.2095-610X.S20211030
Citation: Xiaowei YUAN, Maohua QIN, Lijun WANG, Tingxian YANG, Jing JIN. Expression Characteristics of Inflammatory Factors in the Serum of Patients with Adolescence Polycystic Ovary Syndrome[J]. Journal of Kunming Medical University, 2022, 43(5): 123-126. doi: 10.12259/j.issn.2095-610X.S20220517
shu

Expression Characteristics of Inflammatory Factors in the Serum of Patients with Adolescence Polycystic Ovary Syndrome

doi: 10.12259/j.issn.2095-610X.S20220517

  • Dept. of Traditional Chinese Medicine，Kunming Maternal and Child Health Care Hospital， Kunming Yunnan 650031，China

  • Received Date: 2022-01-27
    Available Online: 2022-05-12
  • Publish Date: 2022-05-27
    Abstract
  •   Objective   To study the expression of CRP, IL-6 and TNF-a in the serum of patients with the suspected adolescence polycystic ovary syndrome （PCOS）.  Methods  80 patients with the suspected adolescence polycystic ovary syndrome （PCOS）were selected as the object of study （suspected adolescence PCOS group）, and 60 patients with adolescence PCOS were chosen as the PCOS group and60 normal adolescence women selected as the control group. The 80 subjects were divided into two subgroups: OA+PCOM group （40 cases） and OA+HA group （40 cases）. The levels of FSH, LH, T, E2, PRL, CRP, IL-6, TNF-a were detected. Results Serum levels of CRP、IL-6 in suspected adolescence PCOS group were significantly higher than those in the control group （P < 0.05）. Serum levels of CRP, TNF-a and IL-6 in OA+HA group were significantly higher than those in OA+PCOM group （P < 0.05）.  Conclusion  The high levels of IL-6 and CRP in patients with the suspected adolescence PCOS may help to identify the early puberty and provide the evidence for the early intervention of adolescence PCOS.
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