Volume 43 Issue 6
Jun.  2022
Turn off MathJax
Article Contents
Ziwei LI, Meiqun GU, Xiaozhi XU, Lianfang TANG, Xiaoyan XU, Jinghui YANG, Kai BI, Hongying MI. Clinical Data Analysis of 101 Cases of Very Preterm Infants[J]. Journal of Kunming Medical University, 2022, 43(6): 85-91. doi: 10.12259/j.issn.2095-610X.S20220610
Citation: Ziwei LI, Meiqun GU, Xiaozhi XU, Lianfang TANG, Xiaoyan XU, Jinghui YANG, Kai BI, Hongying MI. Clinical Data Analysis of 101 Cases of Very Preterm Infants[J]. Journal of Kunming Medical University, 2022, 43(6): 85-91. doi: 10.12259/j.issn.2095-610X.S20220610

Clinical Data Analysis of 101 Cases of Very Preterm Infants

doi: 10.12259/j.issn.2095-610X.S20220610
  • Received Date: 2022-02-06
  • Publish Date: 2022-06-25
  •   Objective   To investigate the birth status, serious complications, outcome and follow-up of very premature infants, and to analyze the influencing factors.   Methods   The clinical data of very preterm infants hospitalized in our department from January 1, 2020 to December 31, 2020 were retrospectively collected. We compared and analyzed the difference of their birth status, perinatal status, treatment and outcome, and compared the physical development of infants who were followed up at 40 weeks, 1 month and 3 months after discharge.   Results   A total of 101 premature infants were investigated. The gestational age was 22+5-31+6 weeks and the average was 29+6 weeks. The birth weight was 440-2100 g, and the average was 1348.21 g. All cases were grouped according to gestational age. All cases were grouped according to gestational age. The number of patients less than 28 weeks was the least, accounting for 10.89%, and the number of patients 30 -30+6 weeks and 31-31+6 weeks were the most, accounting for 27.72% respectively. The older the gestational age, the greater the birth weight, the higher the cesarean section rate, and the higher the Apgar score at 1 minute and 5 minutes. The perinatal related factors in each group were statistically different only in the presence of premature rupture of membranes. In terms of treatment measures, there were significant differences in invasive ventilation time and parenteral nutrition time. In terms of complications, there was significant difference in the incidence of moderate and severe BPD. There were significant differences in hospital stay, improvement rate and abandonment rate among the groups. Among the 75 discharged children who participated in the follow-up of physical development, the average head circumference, average length and average weight of infants of all ages exceeded the P10 percentile, and there was no significant difference between male and female infants.   Conclusion   The younger the gestational age, the longer the need for invasive ventilation and parenteral nutrition, the more prone to premature delivery related complications such as moderate and severe BPD, and the survival rate is also more likely to be affected.
  • loading
  • [1]
    谢幸, 孔北华, 段涛. 妇产科学[M]. 北京: 人民卫生出版社, 2019: 48-162.
    [2]
    邵肖梅, 叶洪瑁, 丘小汕. 实用新生儿学[M]. 第5版, 北京: 人民卫生出版社, 2019: 555-1032.
    [3]
    Fenton T R,Kim J H. A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants[J]. BMC Pediatr,2013,13:59. doi: 10.1186/1471-2431-13-59
    [4]
    De Onis M,Onyango A,Borghi E,et al. Worldwide implementation of the WHO Child Growth Standards[J]. Public Health Nutr,2012,15(9):1603-1610. doi: 10.1017/S136898001200105X
    [5]
    Cao Y,Jiang S,Sun J,et al. Assessment of Neonatal Intensive Care Unit Practices,Morbidity,and Mortality Among Very Preterm Infants in China[J]. JAMA Netw Open,2021,4(8):e2118904. doi: 10.1001/jamanetworkopen.2021.18904
    [6]
    Sun J,Cao Y,Hei M,et al. Data Quality Improvement and Internal Data Audit of the Chinese Neonatal Network Data Collection System[J]. Front Pediatr,2021,9:711200.
    [7]
    多中心极低和超低出生体重儿的预后评估协作组. 超早产儿和超低出生体重儿的死亡原因:多中心前瞻性队列研究[J]. 中华围产医学杂志,2020,23(8):530-538. doi: 10.3760/cma.j.cn113903-20191221-00725
    [8]
    林丽,黄继谦,诸葛张明,等. 超低出生体重儿243例存活率和并发症临床分析[J]. 中华新生儿科杂志(中英文),2017,32(4):259-263.
    [9]
    张小松,杨慧霞. 早产发生的影响因素及其流行病学研究进展[J]. 中华妇产科杂志,2017,52(5):344-347. doi: 10.3760/cma.j.issn.0529-567x.2017.05.013
    [10]
    孔祥永,张珊,封志纯,等. 中国14家医院超/极早产儿早期预后的多中心调查[J]. 中国医刊,2018,53(12):1356-1362. doi: 10.3969/j.issn.1008-1070.2018.12.015
    [11]
    张慧,韩彤妍,朴梅花,等. 1 min低Apgar评分超早产儿/超低出生体重儿的远期结局[J]. 中华围产医学杂志,2017,20(5):366-370. doi: 10.3760/cma.j.issn.1007-9408.2017.05.012
    [12]
    仲秀丽,柏丹丹,郭佳丽,等. 早产儿2098例并发症分析[J]. 南通大学学报(医学版),2021,41(2):181-184.
    [13]
    中国城市多中心早产儿呼吸窘迫综合征调查协作组. 住院分娩早产儿呼吸窘迫综合征:中国13家医院的回顾性调查[J]. 中华围产医学杂志,2016,19(10):743-754. doi: 10.3760/cma.j.issn.1007-9408.2016.10.006
    [14]
    臧月珍,杨阳阳,吕媛,等. 不同胎龄新生儿呼吸窘迫综合征早产儿血细胞分析指标及临床特点[J]. 实用临床医药杂志,2021,25(01):69-73.
    [15]
    张海洋,刘瀚旻. 早产儿生命早期肺发育轨迹研究现状[J]. 中华妇幼临床医学杂志(电子版),2021,17(04):373-379. doi: 10.3877/cma.j.issn.1673-5250.2021.04.001
    [16]
    中华医学会儿科学分会新生儿学组,中华儿科杂志编辑委员会. 早产儿支气管肺发育不良临床管理专家共识[J]. 中华儿科杂志,2020,58(5):358-365. doi: 10.3760/cma.j.cn112140-20200317-00254
    [17]
    陈雯雯,戴淑珍,张震海,等. 胎龄<32周早产儿支气管肺发育不良的危险因素分析[J]. 中国实用医药,2021,16(5):18-21.
    [18]
    陆雅静,陶安宇,李伟,等. 早产儿不同程度脑损伤的超声表现及其临床影响因素分析[J]. 临床超声医学杂志,2019,21(11):811-814. doi: 10.3969/j.issn.1008-6978.2019.11.004
    [19]
    中国医师协会新生儿科医师分会循证专业委员会. 新生儿坏死性小肠结肠炎临床诊疗指南(2020)[J]. 中国当代儿科杂志,2021,23(1):1-11. doi: 10.7499/j.issn.1008-8830.2011145
    [20]
    马俊苓,刘鸽,慕兴波,等. 超早产儿早期存活情况与住院并发症分析[J]. 中华实用儿科临床杂志,2019,34(6):430-434. doi: 10.3760/cma.j.issn.2095-428X.2019.06.012
    [21]
    马俊苓,高琦,刘鸽,等. 超早产儿早产儿视网膜病变的发病情况及危险因素分析[J]. 中华眼底病杂志,2021,37(1):40-46. doi: 10.3760/cma.j.cn511434-20191011-00325
    [22]
    吴子东,庄海容,李成军. 早产儿视网膜病变危险因素及不同分期发病率的回顾性分析[J]. 中国斜视与小儿眼科杂志,2021,29(3):17-20. doi: 10.3969/J.ISSN.1005-328X.2021.03.006
    [23]
    柳雨雨,李海鸿,丁晓华,等. 早产儿脑损伤危险因素的Meta分析[J]. 中国妇幼保健,2021,36(10):2434-2438.
    [24]
    吴新萍,谷传丽,韩树萍,等. 极早产儿存活率和并发症的多中心回顾性研究[J]. 中国当代儿科杂志,2021,23(8):814-820. doi: 10.7499/j.issn.1008-8830.2102037
    [25]
    CAO W,ZHANG Y H,ZHAO D Y,et al. [Risk factors for extrauterine growth restriction in preterm infants with gestational age less than 34 weeks][J]. Zhongguo Dang Dai Er Ke Za Zhi,2015,17(5):453-458.
    [26]
    孟涵燕. 早产儿宫外生长受限研究进展[J]. 临床儿科杂志,2021,39(4):304-307. doi: 10.3969/j.issn.1000-3606.2021.04.017
    [27]
    李小燕,王慧琴,柴竹青,等. 早产儿出院后生长发育监测与随访[J]. 中国儿童保健杂志,2016,24(7):749-752.
  • Relative Articles

    [1] Li MA, Yu'e ZHOU, Jiahui JIANG, Junyao LI, Xiaoyan MU, Yi MA. Effect of Olfactory Comfort Combined with Maternal Voice Stimulation on Sleep in Hospitalized Preterm Infants. Journal of Kunming Medical University, 2024, 45(8): 188-192.  doi: 10.12259/j.issn.2095-610X.S20240827
    [2] Shuang FANG, Libo ZHU, Ling LIU, Yanhua XU, Xue HU. Meta-analysis of the Impact of Early Enteral Nutrition on the Clinical Outcomes of Very Low Birth Weight Premature Infants. Journal of Kunming Medical University, 2024, 45(9): 129-135.  doi: 10.12259/j.issn.2095-610X.S20240920
    [3] Hai ZHOU, Zhongqin YUAN, Yongcun CEN, Yanni LU, Zhihong YAO, Yongchun ZHOU, Yunchao HUANG. Survival Analysis of 1635 Patients with Esophageal Cancer: A Single-Center Retrospective Study. Journal of Kunming Medical University, 2024, 45(8): 67-73.  doi: 10.12259/j.issn.2095-610X.S20240810
    [4] Yongyi ZOU, Zhiye QI, Dongmei SUN, Chunmei Wan, Kun LIANG. Effects of Different Vitamin D Doses on Bone Metabolism and Growth and Development Indicators of Preterm infants:A Cohort Study. Journal of Kunming Medical University, 2023, 44(11): 76-81.  doi: 10.12259/j.issn.2095-610X.S20231111
    [5] Siqi WU, Gang CHEN, Yishuang XIAO. Effect of Comprehensive Treatment for Aggressive Retinopathy of Prematurity. Journal of Kunming Medical University, 2022, 43(5): 127-132.  doi: 10.12259/j.issn.2095-610X.S20220513
    [6] Jiarong YUAN, Ying LIANG, Jian MA, Chao QI, Nan LI. Effect of Early Physical Instruction on Development of Preterm Infants. Journal of Kunming Medical University, 2022, 43(3): 103-107.  doi: 10.12259/j.issn.2095-610X.S20220323
    [7] Zhou Yu E , Yin Li Juan , Yang Hui Bo . . Journal of Kunming Medical University, 2020, 41(02): 168-170.
    [8] Jiang Yan , Mi Hong Ying , Shi Xu Li , Yang Jing Hui , Yang Yong Mei , Tian Yun Fen . . Journal of Kunming Medical University, 2020, 41(06): 120-126.
    [9] Ma Rui , Li Yan . Research Progress of Exposure to Pyrethroid Pesticides Impact on Reproductive System of Human and Physical Development of Infants. Journal of Kunming Medical University, 2019, 40(03): 126-130.
    [10] Zhou Yu E , Yang Zhao Yu , Yin Yan Tao . Effect of Continuous Nursing on Extremely Low Birth Weight Preterm infants Infants. Journal of Kunming Medical University, 2018, 39(03): 137-140.
    [11] Zhou Yu E , Zhang Zheng Ming , Liao Gui . The Clinic Effect of 2-Hour Feeding in Premature Infants with Very Low Birth Weight. Journal of Kunming Medical University, 2018, 39(08): 145-148.
    [12] Wang Yan Yan , Chen Jun Hu , Zhang Xiu Guo , Chen Xiao Yuan . . Journal of Kunming Medical University, 2017, 38(02): 62-65.
    [13] Liu Jing . Effect of Early Intervention in Neurodevelopment on Motor and Cognitive Development of High Risk Premature Infants. Journal of Kunming Medical University,
    [14] Xiong Han Mei . . Journal of Kunming Medical University,
    [15] Hu Qiu Lan . . Journal of Kunming Medical University,
    [16] . Therapeutic Effect of Large Dose of Mucosolvan on Respiratory Distress Syndrome in Premature Children. Journal of Kunming Medical University,
    [17] . . Journal of Kunming Medical University,
    [18] . Comparison of the Clinical Characteristics of Newborn Respiratory Distress Syndrome between Full-term and Premature Infants. Journal of Kunming Medical University,
    [19] Zhang Yi . . Journal of Kunming Medical University,
    [20] . The Follow-up Monitoring and Early Screening of Small Hepatocellular Carcinoma for High Risk Group of Hepatocellular Carcinoma. Journal of Kunming Medical University,
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(6)

    Article Metrics

    Article views (2444) PDF downloads(16) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return