Volume 43 Issue 7
Jul.  2022
Turn off MathJax
Article Contents
Hangcheng TIAN, Ruochuan CHENG, Yingsheng BAO, Yuhua ZHANG, Jun HAN, Hongmei KUANG, Changwei ZHOU. Influence of Different Thyroid Surgery Methods on the Function of Parathyroid Glands[J]. Journal of Kunming Medical University, 2022, 43(7): 92-96. doi: 10.12259/j.issn.2095-610X.S20220719
Citation: Hangcheng TIAN, Ruochuan CHENG, Yingsheng BAO, Yuhua ZHANG, Jun HAN, Hongmei KUANG, Changwei ZHOU. Influence of Different Thyroid Surgery Methods on the Function of Parathyroid Glands[J]. Journal of Kunming Medical University, 2022, 43(7): 92-96. doi: 10.12259/j.issn.2095-610X.S20220719

Influence of Different Thyroid Surgery Methods on the Function of Parathyroid Glands

doi: 10.12259/j.issn.2095-610X.S20220719
  • Received Date: 2022-04-18
    Available Online: 2022-06-25
  • Publish Date: 2022-07-14
  •   Objective  To explore the influence of different thyroid surgery methods on the function of parathyroid glands.   Methods  We analyzed the clinical data of 60 patients undergoing thyroid surgery, including 30 cases in the subtotal thyroidectomy group and 30 cases in the total thyroidectomy group. Then we compared the preoperative PTH, the level of PTH and the degree of decrease in PTH in one week after the operation, as well as the preoperative blood calcium content, the level of blood calcium content and the decrease in blood calcium content one week after the operation.   Results  No difference was found in preoperative clinical data between the two groups (P > 0.05). There was no significant difference in PTH [(46.71±11.52) ng/L vs(46.23±11.74) ng/L, P > 0.05] and blood calcium levels [(1.85±0.47) mmol/L vs(1.88±0.39) mmol/L, P > 0.05] between the two groups before surgery. One week after the operation, the PTH and blood calcium of the two groups were lower than before the operation. The PTH [(23.35±6.42) ng/L vs (32.18±9.51) ng/L, P < 0.05] and blood calcium levels [(1.42±0.31) mmol/L vs (1.75±0.21)mmol/L, P < 0.05] in the total thyroidectomy group were significantly lower than those in the subtotal thyroidectomy group. The degree of decrease in PTH [(49.5±5.1%) vs (31.1±3.5%), P < 0.05] and blood calcium levels [(24.5±2.31%) vs (5.4±0.5%), P < 0.05] were significantly higher than the subtotal thyroidectomy group. Total thyroidectomy group parathyroid detection rate was significantly higher than the subtotal thyroidectomy group (26.67%比3.33%, P < 0.05).   Conclusion  Different thyroid surgery methods will lead to different degrees of postoperative hypoparathyroidism, and total thyroidectomy has a more significant impact than subtotal thyroidectomy.
  • loading
  • [1]
    Kakava K,Tournis S,Makris K,et al. Identification of patients at high risk for postsurgical hypoparathyroidism[J]. In Vivo,2020,34(5):2973-2980. doi: 10.21873/invivo.12128
    [2]
    Paladino N C,Gu é rin C,Graziani J,et al. Predicting risk factors of postoperative hypocalcemia after total thyroidectomy:is safe discharge without supplementation possible? A large cohort study[J]. Langenbeck Arch Surg,2021,406(7):2425-2431. doi: 10.1007/s00423-021-02237-2
    [3]
    Godlewska P,Benke M,Stachlewska-Nasfeter E,et al. Risk factors of permanent hypoparathyroidism after total thyroidectomy and central neck dissection for papillary thyroid cancer:a prospective study[J]. Endokrynol Pol,2020,71(2):126-133. doi: 10.5603/EP.a2020.0006
    [4]
    邓汇典. 不同甲状腺手术方式对甲状旁腺功能损伤的影响比较[J]. 当代医学,2020,26(33):179-180. doi: 10.3969/j.issn.1009-4393.2020.33.079
    [5]
    杨建新. 分析不同手术方式治疗甲状腺癌对甲状旁腺功能的影响[J]. 现代诊断与治疗, 2019, 30(21): 3806-3808.
    [6]
    Mehrabi B M,Jangjoo A,Afzal A M,et al. Transient and permanent hypoparathyroidism following thyroidectomy[J]. Minerva Chir,2012,67(5):433-438.
    [7]
    Ozbas S,Kocak S,Aydintug S,et al. Comparison of the complications of subtotal, near total and total thyroidectomy in the surgical management of multinodular goitre[J]. Endocr J,2005,52(2):199-205.
    [8]
    Yazıcıoğlu M Ö,Yılmaz A,Kocaöz S,Parlak,et al. Risks and prediction of postoperative hypoparathyroidism due to thyroid surgery[J]. Sci Rep,2021,11(1):11876. doi: 10.1038/s41598-021-91277-1
    [9]
    Chahardahmasumi E,Salehidoost R,Amini M,et al. Assessment of the Early and Late Complication after Thyroidectomy[J]. Adv Biomed Res,2019,8:14. doi: 10.4103/abr.abr_3_19
    [10]
    Nawrot I,Woźniewicz B,Tołłoczko T,et al. Allotransplantation of cultured parathyroid progenitor cells withoutimmunosuppression:clinical results[J]. Transplantation,2007,83(6):734-740. doi: 10.1097/01.tp.0000258601.17505.9d
    [11]
    朱精强. 甲状腺手术中甲状旁腺保护专家共识[J]. 中国实用外科杂志,2015,35(7):731-736.
    [12]
    夏恒,刘钊,黄河,等. 甲状腺癌手术中不同手术入路方式对甲状旁腺辨识及功能保护的影响[J]. 全科医学临床与教育,2022,20(3):267-269.
    [13]
    朱国华,邹贤,宋智明,等. 甲状腺不同手术方式对甲状旁腺功能的影响[J]. 中国现代普通外科进展,2014,17(5):342-345.
    [14]
    罗登榜. 甲状旁腺保护技术在甲状腺癌手术中的应用[J]. 医学伦理与实践,2021,34(21):3740-3742.
    [15]
    王登欢,任艳鑫,冯恩梓,等. 经口腔入路甲状腺腔镜手术在治疗甲状腺微小癌的应用价值及美容性效果[J]. 昆明医科大学学报,2020,41(10):119-123.
  • Relative Articles

    [1] Ying LUO, Wenxun DONG, Ying CHEN, Xiangxiu TAN. Research Advances on Lung Function in Patients Undergone Surgery for Lung Cancer. Journal of Kunming Medical University, 2024, 45(4): 177-183.  doi: 10.12259/j.issn.2095-610X.S20240426
    [2] Wei WANG, Ruimei SUN. Advances in Endoscopic Thyroid Surgery. Journal of Kunming Medical University, 2024, 45(4): 184-191.  doi: 10.12259/j.issn.2095-610X.S20240427
    [3] Qingxia YANG, Changrong WU, Juanzhang LUO, Wei WANG, Yahong WANG, Ruimei SUN. Clinical Data Analysis of 108 Patients with Primary Hyperparathyroidism. Journal of Kunming Medical University, 2023, 44(4): 75-81.  doi: 10.12259/j.issn.2095-610X.S20230411
    [4] Wenlin ZHOU, Ben NIU, Heng SU. Analysis of Clinical Risk Factors for Idiopathic Hypogonadotropic Hypogonadism. Journal of Kunming Medical University, 2023, 44(7): 64-68.  doi: 10.12259/j.issn.2095-610X.S20230727
    [5] Wei WANG, Qingxia YANG, Juanzhang LUO, Yahong WANG, Fuke WANG, Ruimei SUN. Efficacy of Transaxillary Approach Endoscopic Thyroid Surgery for the Treatment of Single-Sided Thyroid Cancer. Journal of Kunming Medical University, 2023, 44(12): 65-71.  doi: 10.12259/j.issn.2095-610X.S20231211
    [6] Wanyou JIA, Hongli LIU, Weiwei JIANG, Hongmin LI, Shuo ZHANG, Jimin FEI. Risk Factors for Hypoparathyroidism after Thyroidectomy. Journal of Kunming Medical University, 2022, 43(9): 84-89.  doi: 10.12259/j.issn.2095-610X.S20220904
    [7] Yun-hai MA, Jun QIAN, Shu-ling LI, Ting-ting YAN, Ruo-chuan Cheng. Study on the Morphology and Function of a Single Parathyroid Gland in situ by Endoscopy and Parathyroid Hormone Determination in Drainage Fluid. Journal of Kunming Medical University, 2021, 42(10): 84-91.  doi: 10.12259/j.issn.2095-610X.S20211045
    [8] Ren Xu , Song Hao Nan , Sun Li Hua . . Journal of Kunming Medical University, 2020, 41(06): 140-143.
    [9] Feng Shu Qing , Qin Li , Liu Yan , Yang Xiao Yun , Zeng Ming Hui , Luo Ting Ting , Zong Shao Yun . . Journal of Kunming Medical University, 2019, 40(07): 92-95.
    [10] Wang Qiong , Qi Zhi Ye , Zhao Xiao Long , Zhong Qing Hua , Zhang Cai Ying , Liang Kun , Duan Jiang . The Determination of Cut-off Value of TSH during Screening of Congenital Hypothyroidism in 6 Prefecture/City of Yunnan Province. Journal of Kunming Medical University, 2018, 39(01): 69-72.
    [11] Zhang Hong , Fang Xing Bao , Xu Bin Yong , Wang Zhao Xiong , Ge Jia Yun . Application of Carbon Nano Negative Parathyroid Imaging in Thyroid Cancer Surgery. Journal of Kunming Medical University, 2017, 38(11): 58-61.
    [12] Li Lei , Yang Jie , Wang Wei Lin , Wang Hu . Surgical Treatment Strategy of Thyroid Carcinoma with Hashimoto's Thyroiditis. Journal of Kunming Medical University, 2017, 38(10): 95-100.
    [13] Zheng Jun . Comparison of Clinical Efficacy between Microendoscopic Discectomy and Open Discectomy in the Treatment of Patients with Lumber Intervertebral Disc Herniation. Journal of Kunming Medical University,
    [14] Duan Guo Ming . . Journal of Kunming Medical University,
    [15] Lin Jin . . Journal of Kunming Medical University,
    [16] Rui Qiao An . . Journal of Kunming Medical University,
    [17] Yang Hui . . Journal of Kunming Medical University,
    [18] Li Bing . . Journal of Kunming Medical University,
    [19] Liu Zhan Quan . . Journal of Kunming Medical University,
    [20] Chen Wei Wen . Clinical Study of Subclinical Hypothyroidism during Pregnancy. Journal of Kunming Medical University,
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(2)  / Tables(2)

    Article Metrics

    Article views (2616) PDF downloads(21) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return