Research Progress on Animal Model of Chronic Periapical Periodontitis in SD Rats

Rongyu YANG; Fei SONG; Hao HUANG; Kaiwen DUAN; Shibing QIAN; Yingying XIANG

doi:10.12259/j.issn.2095-610X.S20221005

Volume 43 Issue 10

Oct. 2022

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Article Navigation > Journal of Kunming Medical University > 2022 > 43(10): 163-167

Rongyu YANG, Fei SONG, Hao HUANG, Kaiwen DUAN, Shibing QIAN, Yingying XIANG. Research Progress on Animal Model of Chronic Periapical Periodontitis in SD Rats[J]. Journal of Kunming Medical University, 2022, 43(10): 163-167. doi: 10.12259/j.issn.2095-610X.S20221005

Citation:

Rongyu YANG, Fei SONG, Hao HUANG, Kaiwen DUAN, Shibing QIAN, Yingying XIANG. Research Progress on Animal Model of Chronic Periapical Periodontitis in SD Rats[J]. Journal of Kunming Medical University, 2022, 43(10): 163-167. doi: 10.12259/j.issn.2095-610X.S20221005

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Research Progress on Animal Model of Chronic Periapical Periodontitis in SD Rats

doi: 10.12259/j.issn.2095-610X.S20221005

1.
Dept. of Stomatology, Yan’an Hospital of Kunming City, Kunming Yunnan 650031
2.
Dept. of Minimally Invasive Intervention，The 3rd Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650106，China

Received Date: 2022-06-17
Available Online: 2022-10-08
Publish Date: 2022-10-31

Abstract

Abstract

Chronic periapical periodontitis is a common oral disease secondary to dental pulp infection, which often leads to bone destruction in the apical region because of bacterial infection in the root canal. Because of the particularity of human individuals, in many cases, the dynamic changes of the pathogenesis of periapical tissue can not be directly studied, it is very important to select and establish an appropriate animal model. At present, the animal models commonly used to establish chronic periapical periodontitis mainly include monkeys, dogs, rats and miniature pigs. Among them, SD rats are often used to study the pathogenesis of periapical periodontitis because of their advantages of fast growth, easy culture, strong adaptability, low price, and easy feeding. This paper reviews the research on the animal model of chronic apical periodontitis in SD rats at home and abroad from the aspects of the basis, methods and evaluation methods after the establishment of the model, so as to provide a theoretical basis for the clinical study of the development mechanism and treatment of chronic apical periodontitis.
- SD rats,
- Chronic periapical periodontitis,
- Animal model

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References(29)

References

[1]	Loureiro C,Buzalaf M A R,Moraes F R N,et al. Quantitative proteomic analysis in symptomatic and asymptomatic apical periodontitis[J]. Int Endod J,2021,54:834-847.
[2]	张竹砚. 慢性根尖周炎动物模型的研究进展[J]. 口腔材料器械杂志,2020,29(2):47-51. doi: 10.11752/j.kqcl.2020.02.09
[3]	孔晨,李永丽,李思佳,等. 牙周炎动物模型的研究进展[J]. 医学综述,2019,25(17):3344-3349. doi: 10.3969/j.issn.1006-2084.2019.17.004
[4]	Stashenko P,Wang C Y,Tani-Ishii N,et al. Pathogenesis of induced rat periapical lesions[J]. Oral Surg Oral Med Oral Pathol,1994,78(4):494-502. doi: 10.1016/0030-4220(94)90044-2
[5]	张若芳,雷建锋,王红梅,等. Sprague-Dawley大鼠磨牙早期牙根发育的显微CT研究[J]. 北京口腔医学杂志,2016,24(1):14-15.
[6]	Zhao D F,Guan S Y,Fan Y,et al. Effects of idiopathic hypoparathyroidism on tooth eruption of rats[J]. Chinese Journal of Stomatology,2021,56(9):880-891.
[7]	叶程心月,汤颖,刘超,等. SD大鼠牙列的显微CT观测[J]. 实用口腔医学杂志,2019,35(6):794-799.
[8]	Sharir A,Marangoni P,Zilionis R,et al. A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage[J]. Nat Cell Biol,2019,21(9):1102-1112. doi: 10.1038/s41556-019-0378-2
[9]	Krivanek J,Soldatov R A,Kastriti M E,et al. Dental cell type atlas reveals stem anddifferentiated cell types in mouse and human teeth[J]. Nature Communications,2020,11(1):4816. doi: 10.1038/s41467-020-18512-7
[10]	Vijaykumar A,Mina M. Comparison of osteogenic and dentinogenic potentials of mice incisor and molar pulps in vitro[J]. Archives of Oral Biology,2020,111:104647.
[11]	李燕珠. 髓腔暴露法构建大鼠实验性牙髓炎模型的研究[D]. 福州: 福建医科大学, 2019.
[12]	马典福,陈帅,肖素丽,李萍萍,黄晓晶. 慢性根尖周炎对大鼠血浆炎症因子及主动脉的影响[J]. 口腔医学研究,2019,35(9):872-875.
[13]	Yamasaki M,Kumazawa M,Kohsaka T,et al. Pulpal and periapical tissue reactions after experimental pulpal exposure in rats[J]. J Endod,1994,20(1):13-17.
[14]	Lin Y,Xing Q,Qin W,et al. Decreased Expression of Semaphorin3A/Neuropilin-1 Signaling Axis in Apical Periodontitis[J]. Biomed Res Int,2017,(2):8724503.
[15]	Barbosa-Ribeiro Marlos,Arruda-Vasconcelos Rodrigo,Louzada Lidiane M,et al. Microbiological analysis of endodontically treated teeth with apical periodontitis before and after endodontic retreatment[J]. Clinical Oral Investigations,2021,25(4):2017-2027. doi: 10.1007/s00784-020-03510-2
[16]	Korona-Glowniak I,Piatek D,Fornal E et al. Patterns of Oral Microbiota in Patients with Apical Periodontitis[J]. J Clin Med,2021,10(12):2707. doi: 10.3390/jcm10122707
[17]	Wang Q S,Gao Y,Rong L et al. Radiological and histopathological changes of the periapical lesions induced by lipopolysaccharide in rats[J]. Shanghai Kou Qiang Yi Xue,2008,17(4):416-419.
[18]	Yuanita T,Kunarti S,Zubaidah N. East java extract propolis as potential intracanal medicament in experimentally induced chronic apical periodontitis[J]. Indian J Dent Res,2019,30:342-346.
[19]	Wang L,Jin H,Ao X et al. JAK2-STAT3 signaling pathway is involved in rat periapical lesions induced by Enterococcus faecalis[J]. Oral Dis,2019,25(7):1769-1779. doi: 10.1111/odi.13169
[20]	王佳佳,刘杰,王敏. 构建具核梭杆菌诱导的实验性根尖周炎小鼠模型[J]. 中国组织工程研究,2022,26(2):184-189.
[21]	Ye Qin, Feng Yao, Zhao Yaqiong, et al. Comparison of EASYDO ACTIVATOR, passive ultrasonic, and needle irrigation techniques on the treatment of apical periodontitis: a study in rats[J]. Clinical Oral Investigations, 2022, doi: 10.1007/s00784-022-04677-6
[22]	Goldman Elisheva, Reich Eli, Roshihotzki Bar, et al. A Mouse Model for Studying the Development of Apical Periodontitis with Age[J]. Cells, 2021, 10 （3）: 1-15.
[23]	Yang S,Zhu L,Xiao L,et al. Imbalance of interleukin-17+ T-cell and Foxp3+ regulatory T-cell Dynamics in Rat Periapical Lesions[J]. Journal of Endodontics,2014,40(1):56-62. doi: 10.1016/j.joen.2013.09.033
[24]	Tsutsumi T,Kajiya H,Tsuzuki T,et al. Micro-computed tomography for evaluating alveolar bone resorption induced by hyperocclusion[J]. Journalof Prosthodontic Research,2017,62:298-302.
[25]	Schweitzer C,Garrido M,Paredes R,et al. Localization of interleukin-6 signaling complex in epithelialized apical lesions of endodontic origin[J]. Clinical Oral Investigations,2021,25(6):4075-4083. doi: 10.1007/s00784-020-03738-y
[26]	Azuma M M,Samuel R O,Gomes-Filho J E,et al. The role of IL-6 on apical periodontitis:A systematic review[J]. International Endodontic Journal,2014,47(7):615-621. doi: 10.1111/iej.12196
[27]	Silva R A B,Sousa-Pereira A P,Lucisano M P,et al. Alendronate inhibits osteocyte apoptosis and inflammation via IL-6,inhibiting bone resorption in periapical lesions of ovariectomized rats[J]. International Endodontic Journal,2020,53(1):84-96. doi: 10.1111/iej.13206
[28]	Jakovljevic Aleksandar,Nikolic Nadja,Jacimovic Jelena,et al. Tumor Necrosis Factor Alpha -308 G/A Single-Nucleotide Polymorphism and Apical Periodontitis:An Updated Systematic Review and Meta-analysis[J]. Journal of Endodontics,2021,47(7):1061-1069. doi: 10.1016/j.joen.2021.03.007
[29]	Tsosura T V S,Chiba F Y,Mattera M S L C,et al. Maternal apical periodontitis is associated with insulin resistance in adult offspring[J]. International Endodontic Journal,2019,52(7):1040-1050. doi: 10.1111/iej.13096

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