Preliminary Study on HPV Screening Results and Genotyping of 6 091 Women in Kunming

Xinyi LI; Yan ZHU; Rongxia HUANG

doi:10.12259/j.issn.2095-610X.S20221010

Volume 43 Issue 10

Oct. 2022

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Xinyi LI, Yan ZHU, Rongxia HUANG. Preliminary Study on HPV Screening Results and Genotyping of 6 091 Women in Kunming[J]. Journal of Kunming Medical University, 2022, 43(10): 143-146. doi: 10.12259/j.issn.2095-610X.S20221010

Citation:

Xinyi LI, Yan ZHU, Rongxia HUANG. Preliminary Study on HPV Screening Results and Genotyping of 6 091 Women in Kunming[J]. Journal of Kunming Medical University, 2022, 43(10): 143-146. doi: 10.12259/j.issn.2095-610X.S20221010

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Preliminary Study on HPV Screening Results and Genotyping of 6 091 Women in Kunming

doi: 10.12259/j.issn.2095-610X.S20221010

1.
Dept. of Pharmacy
2.
Dept. of Women’s Health，Kunming Maternity and Child Health Hospital，Kunming Yunnan 650031，China

Received Date: 2022-06-11
Available Online: 2022-10-08
Publish Date: 2022-10-31

Abstract

Abstract

Objective To investigate HPV infection, subtype distribution, and age distribution in females in Kunming. Methods Flow fluorescence hybridization was used to detect HPV genotypes in 6091 female cervical exserted cells in Kunming Maternal and Child Health Hospital in 2021. Infection rate, gene subtypes and age distribution were obtained after classification and statistics. Results 1301 people wereinfected with HPV, the infection rate was 21.36%. Single infected persons accounted for the majority （78.94%）. In all positive specimens, the number of high-risk infection cases was more than that of low-risk infection cases. The highest infection rates were HPV52 （21.83%）, HPV16 （11.38%）, and HPV58 （10.76%）, respectively. Participants were divided into ≤20 years old group, 21 to 30 years old group, 31 to 40 years old group, 41 to 50 years old group, 51 to 60 years old grou, p and > 60 years old group according to age. The HPV infection rate was highest in the > 60 years old group, followed by the 21 to 30 years old group and the 51 to 60 years old group. Conclusions HPV infection in women in Kunming is mainly a hhigh-risk type. Elderly and people under 30 years old need to strengthen prevention and treatment education, and it is recommended that women of appropriate age receive multivalent cervical cancer vaccine as soon as possible.
- Human papillomavirus,
- Gene subtype distribution,
- Age,
- HPV vaccine

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References(15)

References

[1]	谢幸, 孔北华, 段涛. 妇产科学[M]. 第9版. 北京: 人民卫生出版社, 2018: 295-299.
[2]	樊尚荣,刘丹(编译). 2015年美国疾病控制中心性传播疾病的诊断和治疗指南(续)—人乳头瘤病毒感染的诊断和治疗指南[J]. 中国全科医学,2015,18(29):3513-3515.
[3]	Castle P E,Pierz A,Stoler M H. A systematic review andmeta-analysis on the attribution of human papillomavirus (HPV)inneuroendocrine cancers of the cervix[J]. Gynecol Oncol,2018,148(2):422-429. doi: 10.1016/j.ygyno.2017.12.001
[4]	中国抗癌协会妇科肿瘤专业委员会. 子宫颈癌诊断与治疗指南(2021年版)[J]. 中国癌症杂志,2021,31(6):474-489.
[5]	中华人民共和国国家卫生健康委员会. 宫颈癌诊疗规范(2018年版)[J]. 肿瘤综合治疗电子杂志,2020,6(3):33-43.
[6]	王中安,郭清江,乔林爽,等. 蚌埠地区3408例女性宫颈HPV感染状况及基因亚型分布[J]. 分子诊断与治疗杂志,2022,14(1):157-160.
[7]	张爱凤,韩娜,胡玉玲. 北京通州地区妇女HPV亚型分布及感染状况及危险因素分析[J]. 公共卫生与预防医学,2019,30(6):95-98.
[8]	王睿,卜范峰,田欣欣,等. 山东地区女性人乳头瘤病毒感染亚型、多重感染情况及年龄分布差异[J]. 中国生物制品学杂志,2016,29(1):57-60.
[9]	Valentino K,Poronsky C B. Human papillomavirus infection and vaccination[J]. J Pediatr Nurs,2016,31(2):e155-166. doi: 10.1016/j.pedn.2015.10.005
[10]	Satterwhite C L,Torrone E,Meites E,et al. Sexually transmitted infections among US women and men:prevalence and incidence estimates,2008[J]. Sex Transm Dis,2013,40(3):187-193. doi: 10.1097/OLQ.0b013e318286bb53
[11]	唐凤祝,简洁,梁开如,等. 21776例女性人乳头瘤病毒感染情况及亚型分布与宫颈细胞病变的相关性分析[J]. 中国计划生育和妇产科,2021,13(5):92-96.
[12]	李翔,马宁耶,张瑶. 4万余例沈阳地区妇女HPV感染情况分析[J]. 现代肿瘤医学,2022,30(5):884-887.
[13]	钟慧钰,刘堂喻亨,王旻晋,等. 流式荧光杂交技术检测四川大学华西医院体检女性人乳头瘤病毒感染亚型分布[J]. 华西医学,2019,34(8):895-899.
[14]	Althoff K N,Paul P,Burke A E,et al. Correlates of cervicovaginal human papillomavirus detection in perimenopausal women[J]. J Womens Health (Larchmt),2009,18(9):1341-1346. doi: 10.1089/jwh.2008.1223
[15]	何志晖,寇增强,徐爱强. HPV感染及其免疫预防[J]. 中华预防医学杂志,2018,52(1):106-112.

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