Expression of CRP，IL-6 and TNF-a  in Serum of Patients with Adolescence Polycystic Ovary Syndrome

Xiaowei YUAN; Maohua QIN; Lijun WANG; Yuanqi DUAN

doi:10.12259/j.issn.2095-610X.S20221026

Volume 43 Issue 10

Oct. 2022

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Article Navigation > Journal of Kunming Medical University > 2022 > 43(10): 136-138

Xiaowei YUAN, Maohua QIN, Lijun WANG, Yuanqi DUAN. Expression of CRP，IL-6 and TNF-a in Serum of Patients with Adolescence Polycystic Ovary Syndrome[J]. Journal of Kunming Medical University, 2022, 43(10): 136-138. doi: 10.12259/j.issn.2095-610X.S20221026

Citation:

Xiaowei YUAN, Maohua QIN, Lijun WANG, Yuanqi DUAN. Expression of CRP，IL-6 and TNF-a in Serum of Patients with Adolescence Polycystic Ovary Syndrome[J]. Journal of Kunming Medical University, 2022, 43(10): 136-138. doi: 10.12259/j.issn.2095-610X.S20221026

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Expression of CRP，IL-6 and TNF-a in Serum of Patients with Adolescence Polycystic Ovary Syndrome

doi: 10.12259/j.issn.2095-610X.S20221026

Dept. of Gynecology，Kunming Maternal and Child Health Care Hospital， Kunming Yunnan 650031，China

Received Date: 2022-01-01
Available Online: 2022-10-09
Publish Date: 2022-10-31

Abstract

Abstract

Objective To study the expression of CRP, IL-6 and TNF-a in the serum of patients with Adolescence polycystic ovary syndrome （PCOS）. Methods Patients with Adolescence polycystic ovary syndrome（PCOS）were selected as the observation group （100cases）, and 70 routine medical examination Adolescence women as the control group. The levels of CRP, IL-6, TNF-a, fasting plasma glucose （FPG）and fasting serum insulin （FINS） were detected Insulin Resistance Index （HOMA-IR） was calculated. Results Serum levels of CRP, TNF-a, IL-6 and HOMA-IR in PCOS group were significantly higher than those in the control group （P < 0.05）. The levels of CRP, TNF-a and IL-6 in the obese PCOS group were higher than those in the non-obese PCOS group （P < 0.05）. Conclusion The serum levels of CRP, TNF-a and IL-6 were significantly increased in Adolescent PCOS patients, which suggested that inflammatory factors might be involved in the pathogenesis of Adolescence polycystic ovary syndrome.
- Adolescence polycystic ovary syndrome,
- Inflammatory factors,
- Early intervention

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References(11)

References

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