Value of Dual-energy CT Spectrum Curve from Primary Tumor in Prediction of Central Occult Lymph Node Metastasis in Papillary Thyroid Cancer

Wen ZHAO; Tengfei KE; Xingyue HU; Renjie ZHAO

doi:10.12259/j.issn.2095-610X.S20221028

Volume 43 Issue 10

Oct. 2022

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Wen ZHAO, Tengfei KE, Xingyue HU, Renjie ZHAO. Value of Dual-energy CT Spectrum Curve from Primary Tumor in Prediction of Central Occult Lymph Node Metastasis in Papillary Thyroid Cancer[J]. Journal of Kunming Medical University, 2022, 43(10): 74-78. doi: 10.12259/j.issn.2095-610X.S20221028

Citation:

Wen ZHAO, Tengfei KE, Xingyue HU, Renjie ZHAO. Value of Dual-energy CT Spectrum Curve from Primary Tumor in Prediction of Central Occult Lymph Node Metastasis in Papillary Thyroid Cancer[J]. Journal of Kunming Medical University, 2022, 43(10): 74-78. doi: 10.12259/j.issn.2095-610X.S20221028

Citation:

Wen ZHAO, Tengfei KE, Xingyue HU, Renjie ZHAO. Value of Dual-energy CT Spectrum Curve from Primary Tumor in Prediction of Central Occult Lymph Node Metastasis in Papillary Thyroid Cancer[J]. Journal of Kunming Medical University, 2022, 43(10): 74-78. doi: 10.12259/j.issn.2095-610X.S20221028

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Value of Dual-energy CT Spectrum Curve from Primary Tumor in Prediction of Central Occult Lymph Node Metastasis in Papillary Thyroid Cancer

doi: 10.12259/j.issn.2095-610X.S20221028

1.
Dept. of Medical Imaging，The 1st Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650032
2.
Dept. of Radiology，Yunnan Tumour Hospital，Kunming Yunnan 650118，China

Received Date: 2022-01-01
Available Online: 2022-10-09
Publish Date: 2022-10-31

Abstract

Abstract

Objective To predict the probability of occult lymph node metastasis （OLM） in the central region of the neck by analyzing the dual-energy CT energy spectrum curve of thyroid papillary carcinoma （PTC）. Methods Patients with PTC confirmed by pathology before and after operation were retrospectively collected. CT images were analyzed by radiologists. There were 140 cases without cervical lymph node metastasis. Among them, 88 patients with occult lymph node metastasis in the central group （OLM+） and 52 patients without metastasis （OLM−） were confirmed by pathology. The CT value of PTC on each single energy image was measured and the slope （k） of the energy spectrum curve was calculated. The differences in parameters between the two groups were analyzed. Results （1） the k_arterial, 40 keV_arterial, 40 keV_venous, 160 keV_venous and 180 keV_venous of PTC between OLM+ group and OLM− group in arterial and venous phase were significantly different （P < 0.05）. （2） The AUC of 40 keV_arterial, k_arterial, 40 keV_venous, 160 keV_venous and 180 keV_venous in PTC were 0.590, 0.622, 0.590, 0.429 and 0.424 respectively. When k_arterial = 2.563, the sensitivity and accuracy of diagnosing PTC with OLM in the central group were 93.2% and 69.3%. When 40 keV_venous = 370.25, the specificity of PTC with OLM was 86.5%. Conclusion The energy spectrum curve of PTC has a certain reference value in predicting occult lymph node metastasis in the central region of the neck. k_arterial has the highest sensitivity and 40 keV_venous has the highest specificity.
- Thyroid papillary carcinoma,
- Computed tomography,
- Lymph node metastasis,
- Cervical central lymph node

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References(18)

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