Correlation of Frontal Planar QRS-T and Tp-e/QTc Ratio with  Coronary Slow Flow Phenomenon

Meng ZHOU; Hongshan ZHANG; Kanghui GE; lin ZHANG; Xue HAN

doi:10.12259/j.issn.2095-610X.S20221030

Volume 43 Issue 10

Oct. 2022

Turn off MathJax

Article Contents

Article Navigation > Journal of Kunming Medical University > 2022 > 43(10): 147-152

Meng ZHOU, Hongshan ZHANG, Kanghui GE, lin ZHANG, Xue HAN. Correlation of Frontal Planar QRS-T and Tp-e/QTc Ratio with Coronary Slow Flow Phenomenon[J]. Journal of Kunming Medical University, 2022, 43(10): 147-152. doi: 10.12259/j.issn.2095-610X.S20221030

Citation:

Meng ZHOU, Hongshan ZHANG, Kanghui GE, lin ZHANG, Xue HAN. Correlation of Frontal Planar QRS-T and Tp-e/QTc Ratio with Coronary Slow Flow Phenomenon[J]. Journal of Kunming Medical University, 2022, 43(10): 147-152. doi: 10.12259/j.issn.2095-610X.S20221030

Citation:

PDF( 726 KB)

Correlation of Frontal Planar QRS-T and Tp-e/QTc Ratio with Coronary Slow Flow Phenomenon

doi: 10.12259/j.issn.2095-610X.S20221030

1.
Dept. of Cardiac Function，The Second Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650101
2.
Dept. of Cardiology，Fuwai Cardiovascular Hospital of Yunnan Province，Kunming Yunnan 650102，China

Received Date: 2022-06-13
Available Online: 2022-10-09
Publish Date: 2022-10-31

Abstract

Abstract

Objective To investigate the relationship between electrocardiographic frontal QRS-T angle, Tp-e/QTc ratio, and coronary slow flow phenomenon （CSFP） and evaluate the predictive value of frontal QRS-T angle and Tp-e/QTc ratio. Methods Seventy-three patients with CSFP diagnosed by coronary angiography in our hospital from September 2019 to December 2021 were selected as the study group, and 67 patients with the normal coronary flow in the same period were randomly selected as the control group. The clinical data, related ECG parameters, and laboratory indexes of the two groups were compared. Multivariate Logistic regression analysis was used to analyze the risk factors affecting the risk factors of CSFP. The receiver operating characteristic （ROC） curve was drawn to explore the predictive value of frontal QRS-T angle and Tp-e/QTc ratio. Results Compared with the control group, frontal QRS-T angle, Tp-e interval, Tp-e / Qt ratio, Tp-e / QTc ratio, BMI, Cr, RBC, Hb, and HCT were higher, and the two groups were statistically different （all P < 0.05）. In the multivariate Logistic regression analysis show that BMI （OR = 1.137, P = 0.014）、Cr （OR = 1.048, P = 0.004）, frontal QRS-T angle （OR = 1.020, P = 0.003）, Tp-e/QTc （IQR） grade OR = 1.960, P < 0.001） were independent risk factors for CSFP. ROC curve analysis displayed that the diagnostic cut-off value of frontal QRS-T angle was 45.5 degree, The area under the curve was 0.706, and the sensitivity and specificity were 56.2% and 80.1%, respectively; the diagnostic cut-off value of CSFP for Tp-Te/QTc ratio was 0.22, the area under the curve was 0.68, and the sensitivity and specificity were 66% and 66%, respectively. 69%. Conclusion Frontal QRS-T angle and Tp-e/QTc ratio were associated with CSFP, which had a certain potential predictive value for the occurrence of CSFP.
- Electrocardiogram,
- Coronary slow flow phenomenon,
- Frontal QRS-T angle,
- Tp-e/QTc ratio

FullText(HTML)

References(20)

References

[1]	Tambe A A,Demany M A,Zimmerman H A,et al. Angina pectoris and slow flow velocity of dye in coronary arteries-a new angiographic finding[J]. Am Heart J,1972,84(1):66-71. doi: 10.1016/0002-8703(72)90307-9
[2]	Wang X,Nie S P. The coronary slow flow phenomenon:characteristics,mechanisms and implications[J]. Cardiovascular diagnosis and therapy,2011,1(1):37-43.
[3]	XIA S,Deng S B,Wang Y,et al. Clinical analysis of the risk factors of slow coronary flow[J]. Heart and vessels,2011,26(5):480-6. doi: 10.1007/s00380-010-0081-5
[4]	Beltrame J F,Limaye S B,Horowitz J D. The coronary slow flow phenomenon-a new coronary microvascular disorder[J]. Cardiology,2002,97(4):197-202. doi: 10.1159/000063121
[5]	Işık F,Aslan B,Çap M,et al. The relationship between coronary slow-flow and frontal QRS-T angle[J]. Journal of electrocardiology,2021,66:43-47. doi: 10.1016/j.jelectrocard.2021.03.003
[6]	Beltrame J F. Defining the coronary slow flow phenomenon[J]. Circulation journal:official journal of the Japanese Circulation Society,2012,76(4):818-820. doi: 10.1253/circj.CJ-12-0205
[7]	Voulgari C,Pagoni S,Tesfaye S,et al. The spatial QRS-T angle:implications in clinical practice[J]. Current cardiology reviews,2013,9(3):197-210. doi: 10.2174/1573403X113099990031
[8]	Zhang X,Zhu Q,Zhu L,et al. Spatial/Frontal QRS-T Angle Predicts All-Cause Mortality and Cardiac Mortality:A Meta-Analysis[J]. PloS one,2015,10(8):e0136174. doi: 10.1371/journal.pone.0136174
[9]	Zhang Z M,Rautaharju P M,Prineas R J,et al. Electrocardiographic QRS-T angle and the risk of incident silent myocardial infarction in the Atherosclerosis Risk in Communities study[J]. Journal of electrocardiology,2017,50(5):661-666. doi: 10.1016/j.jelectrocard.2017.05.001
[10]	Yazici M,Demircan S,Durna K,et al. The role of adrenergic activity in slow coronary flow and its relationship to TIMI frame count[J]. Angiology,2007,58(4):393-400. doi: 10.1177/0003319707305118
[11]	剡冬冬,彭瑜,赵晶,等. 冠状动脉慢血流现象临床危险因素及形态学研究[J]. 中国介入心脏病学杂志,2021,29(1):29-34. doi: 10.3969/j.issn.1004-8812.2021.01.007
[12]	Ziegler R,Bloomfield D K. A study of the normal QRS-T angle in the frontal plane[J]. Journal of electrocardiology,1970,3(2):161-167. doi: 10.1016/S0022-0736(70)80009-7
[13]	Schmitt N,Grunnet M,Olesen S P. Cardiac potassium channel subtypes:new roles in repolarization and arrhythmia[J]. Physiological reviews,2014,94(2):609-653. doi: 10.1152/physrev.00022.2013
[14]	Zehir R,Karabay C Y,Kalaycı A,et al. Evaluation of Tpe interval and Tpe/QT ratio in patients with slow coronary flow[J]. Anatolian journal of cardiology,2015,15(6):463-467.
[15]	Chua K C,Rusinaru C,Reinier K,et al. Tpeak-to-Tend interval corrected for heart rate:A more precise measure of increased sudden death risk?[J]. Heart rhythm,2016,13(11):2181-2185. doi: 10.1016/j.hrthm.2016.08.022
[16]	Karaman K,Altunkaş F,Çetin M,et al. New markers for ventricular repolarization in coronary slow flow:Tp-e interval,Tp-e/QT ratio,and Tp-e/QTc ratio[J]. Annals of noninvasive electrocardiology:the official journal of the International Society for Holter and Noninvasive Electrocardiology,Inc,2015,20(4):338-344. doi: 10.1111/anec.12203
[17]	Atak R,Turhan H,Sezgin A T,et al. Effects of slow coronary artery flow on QT interval duration and dispersion[J]. Annals of noninvasive electrocardiology:the official journal of the International Society for Holter and Noninvasive Electrocardiology,Inc,2003,8(2):107-111. doi: 10.1046/j.1542-474X.2003.08203.x
[18]	Hawkins B M,Stavrakis S,Rousan T A,et al. Coronary slow flow-prevalence and clinical correlations[J]. Circulation journal:official journal of the Japanese Circulation Society,2012,76(4):936-942. doi: 10.1253/circj.CJ-11-0959
[19]	Ozyurtlu F,Yavuz V,Cetin N,et al. The association between coronary slow flow and platelet distribution width among patients with stable angina pectoris[J]. Postepy w kardiologii interwencyjnej = Advances in interventional cardiology,2014,10(3):161-165.
[20]	Canga A,Cetin M,Kocaman S A,et al. Increased serum resistin levels in patients with coronary slow-flow phenomenon[J]. Herz,2013,38(7):773-778. doi: 10.1007/s00059-013-3758-6

Relative Articles(20)

Relative Articles

[1]	Juan ZHAO, Teng-can TU, Mei-jun YANG, Xiao-yong ZHANG, Wei PAN. Assessment of Early Coronary Artery Disease in Patients with Acute Coronary Syndrome. Journal of Kunming Medical University, 2021, 42(12): 47-50. doi: 10.12259/j.issn.2095-610X.S20211219
[2]	Li-yong WU, Yuan CHEN, Tian-shu CHU, Qing-wen ZHENG, Guo-fu ZHU. Association of Leptin and Leptin Receptor Gene Polymorphism with Coronary Slow Flow Phenomenon. Journal of Kunming Medical University, 2021, 42(3): 109-114. doi: 10.12259/j.issn.2095-610X.S20210328
[3]	Ye Xue Qun , Nie Lei . . Journal of Kunming Medical University, 2017, 38(02): 95-98.
[4]	Luo Lin Ping , Liu Ming Yan , Wu Xiang , Nie Lei . Correlation between ECG Changes and Coronary Angiography of Acute Myocardial Infarction. Journal of Kunming Medical University, 2017, 38(01): 113-116.
[5]	Li Yi Lin . . Journal of Kunming Medical University,
[6]	Gai Qi Ming . . Journal of Kunming Medical University,
[7]	Lai Hai Bo . . Journal of Kunming Medical University,
[8]	Feng Zhen Xia . . Journal of Kunming Medical University,
[9]	Min Jie Qing . . Journal of Kunming Medical University,
[10]	Wu Jian . . Journal of Kunming Medical University,
[11]	Li Bo . . Journal of Kunming Medical University,
[12]	Peng Min An . . Journal of Kunming Medical University,
[13]	Peng Min An . . Journal of Kunming Medical University,
[14]	Min Jie Qing . . Journal of Kunming Medical University,
[15]	Chen Ji Li . . Journal of Kunming Medical University,
[16]	Li Fei . . Journal of Kunming Medical University,
[17]	Liu Meng Si . . Journal of Kunming Medical University,
[18]	Yang Fang . . Journal of Kunming Medical University,
[19]	Fu Zhong Yang . . Journal of Kunming Medical University,
[20]	Li Hua Ping . . Journal of Kunming Medical University,