Effect Analysis of Emergency Endoscopic Treatment for Anastomotic Hemorrhage after Colorectal Cancer Resection

Helong CHE; Zhijin LI; Keqiang WANG; Weiming QIU; Yi CAO; Laibin LUO

doi:10.12259/j.issn.2095-610X.S20221032

Volume 43 Issue 10

Oct. 2022

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Helong CHE, Zhijin LI, Keqiang WANG, Weiming QIU, Yi CAO, Laibin LUO. Effect Analysis of Emergency Endoscopic Treatment for Anastomotic Hemorrhage after Colorectal Cancer Resection[J]. Journal of Kunming Medical University, 2022, 43(10): 122-126. doi: 10.12259/j.issn.2095-610X.S20221032

Citation:

Helong CHE, Zhijin LI, Keqiang WANG, Weiming QIU, Yi CAO, Laibin LUO. Effect Analysis of Emergency Endoscopic Treatment for Anastomotic Hemorrhage after Colorectal Cancer Resection[J]. Journal of Kunming Medical University, 2022, 43(10): 122-126. doi: 10.12259/j.issn.2095-610X.S20221032

Citation:

Helong CHE, Zhijin LI, Keqiang WANG, Weiming QIU, Yi CAO, Laibin LUO. Effect Analysis of Emergency Endoscopic Treatment for Anastomotic Hemorrhage after Colorectal Cancer Resection[J]. Journal of Kunming Medical University, 2022, 43(10): 122-126. doi: 10.12259/j.issn.2095-610X.S20221032

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Effect Analysis of Emergency Endoscopic Treatment for Anastomotic Hemorrhage after Colorectal Cancer Resection

doi: 10.12259/j.issn.2095-610X.S20221032

1.
Dept. of General Surgery，908th Hospital of The People’s Liberation Army Joint Logistic Support Force，Nanchang Jiangxi 330000
2.
Dept. of Gastroenterology，908th Hospital of The People’s Liberation Army Joint Logistic Support Force，Nanchang Jiangxi 330000
3.
Dept. of Gastrointestinal Surgery，The 1st Affiliated Hospital of Nanchang University， Nanchang Jiangxi 330000，China

Received Date: 2022-06-15
Available Online: 2022-10-09
Publish Date: 2022-10-31

Abstract

Abstract

Objective To analyze the efficacy of emergency endoscopic hemostasis in patients with anastomotic hemorrhage after surgical resection of colorectal cancer. Methods The clinical data of patients with anastomotic hemorrhage after surgical resection of colorectal tumor and emergency endoscopic hemostasis were collected from January 2005 to December 2021 in 908th hospital of The People's Liberation Army Joint Logistic Support Force. The demographic data, tumor site, tumor stage and pathological type were analyzed. Of which, the time of anastomotic hemorrhage, hemostasis methods, effects and complications of endoscopic treatment, and the reasons for the failure of endoscopic hemostasis were analyzed selectively. Results Among 1 058 patients undergoing colorectal cancer surgery, 36 patients had anastomotic bleeding （3.4%）. The left colon and rectum cancer were the most patients with hemorrhage （83.3%）. In terms of tumor staging and differentiation, most of the patients were from stage Ⅰ to stage Ⅲ （82.1%）. The pathology was dominated by highly and moderately differentiated cancers （86.1%）. Anastomotic hemorrhage occurred within 72 hours after surgical resection in 26 patients （72.2%）, which was the time of high incidence of hemorrhage. Among the 36 patients, endoscopic hemostasis was successful in 32 cases （88.9%）, in which titanium clip and electrocoagulation combined with titanium clip were the main hemostasis methods （88.9%）. Beside, 4 patients failed to hemostasis by endoscopy, all of them had anastomotic leakage and could not identify the exact bleeding site, and all successfully hemostasis by surgical treatment. No serious complications such as anastomotic leakage, abdominal abscess or death occurred in all 36 patients. Conclusion The peak period of anastomotic hemorrhage is within 72 hours after surgical resection for colorectal cancer. Emergency endoscopic hemostasis is a safe and effective treatment for anastomotic hemorrhage.
- Colorectal cancer,
- Anastomotic hemorrhage,
- Endoscopic hemostasis,
- Effect analysis

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References(15)

References

[1]	Wu Y,Li Y,Giovannucci E. Potential impact of time trend of lifestyle risk factors on burden of major gastrointestinal cancers in china[J]. Gastroenterology,2021,161(6):1830-1841. doi: 10.1053/j.gastro.2021.08.006
[2]	Sung H,Ferlay J,Siegel R L,et al. Global cancer statistics 2020:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin,2021,71(3):209-249. doi: 10.3322/caac.21660
[3]	Zheng R,Zhang S,Zeng H,et al. Cancer incidence and mortality in china,2016[J]. Journal of the National Cancer Center,2022,2(1):1-9. doi: 10.1016/j.jncc.2022.02.002
[4]	Shi J F,Wang L,Ran J C,et al. Clinical characteristics,medical service utilization,and expenditure for colorectal cancer in China,2005 to 2014:Overall design and results from a multicenter retrospective epidemiologic survey[J]. Cancer,2021,127(11):1880-1893. doi: 10.1002/cncr.33445
[5]	Davis B,Rivadeneira D E. Complications of colorectal anastomoses:leaks,strictures,and bleeding[J]. Surg Clin North Am,2013,93(1):61-87. doi: 10.1016/j.suc.2012.09.014
[6]	Hébert J,Eltonsy S,Gaudet J,et al. Incidence and risk factors for anastomotic bleeding in lower gastrointestinal surgery[J]. BMC Res Notes,2019,12(1):378. doi: 10.1186/s13104-019-4403-0
[7]	崔英姿,杨东辉,王晓凤. 吻合口溃疡出血的内镜下特点及治疗[J]. 临床和实验医学杂志,2010,09(15):1125-1127. doi: 10.3969/j.issn.1671-4695.2010.15.003
[8]	Steger J,Jell A,Ficht S,et al. Systematic review and meta-analysis on colorectal anastomotic techniques[J]. Ther Clin Risk Manag,2022,18:523-539. doi: 10.2147/TCRM.S335102
[9]	沈伯明,俞伟君,王永锋. 结直肠癌术后吻合口早期出血的原因及预防措施[J]. 临床医学,2018,38(10):33-34. doi: 10.19528/j.issn.1003-3548.2018.10.011
[10]	Fakas S,Elias M,Lim D,et al. Comparison of gastrojejunostomy techniques and anastomotic complications:a systematic literature review[J]. Surg Endosc,2021,35(12):6489-6496. doi: 10.1007/s00464-020-08142-x
[11]	Perez R O,Sousa A Jr,Bresciani C,et al. Endoscopic management of postoperative stapled colorectal anastomosis hemorrhage[J]. Tech Coloproctol,2007,11(1):64-66. doi: 10.1007/s10151-007-0330-5
[12]	吴轲,古俊楠,曹英豪,等. 急诊内镜诊疗在结直肠癌根治术后吻合口出血中的应用[J]. 腹部外科,2021,34(1):40-43.
[13]	Malik A H,East J E,Buchanan G N,et al. Endoscopic hemostasis of staple-line hemorrhage following colorectal resection[J]. Colorectal Disease,2010,10(6):616-618.
[14]	Gralnek I M,Stanley A J,Morris A J,et al. Endoscopic diagnosis and management of nonvariceal upper gastrointestinal hemorrhage (NVUGIH):European society of gastrointestinal endoscopy (ESGE) guideline - update 2021[J]. Endoscopy,2021,53(3):300-332. doi: 10.1055/a-1369-5274
[15]	Wichmann D,Fusco S,Werner C R,et al. Endoscopic management for post-surgical complications after resection of esophageal cancer[J]. Cancers (Basel),2022,14(4):980. doi: 10.3390/cancers14040980

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