Risk Factors Analysis and Assessment of Ruptured Posterior Communicating Artery Aneurysm

Yuhao DING; Jianren WANG; Tao XIE; Liqing LIN; Zexi LIN; Weiwei ZHU; Xi’an FU; Jun PU

doi:10.12259/j.issn.2095-610X.S20221210

Volume 43 Issue 12

Dec. 2022

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Yuhao DING, Jianren WANG, Tao XIE, Liqing LIN, Zexi LIN, Weiwei ZHU, Xi’an FU, Jun PU. Risk Factors Analysis and Assessment of Ruptured Posterior Communicating Artery Aneurysm[J]. Journal of Kunming Medical University, 2022, 43(12): 47-52. doi: 10.12259/j.issn.2095-610X.S20221210

Citation:

Yuhao DING, Jianren WANG, Tao XIE, Liqing LIN, Zexi LIN, Weiwei ZHU, Xi’an FU, Jun PU. Risk Factors Analysis and Assessment of Ruptured Posterior Communicating Artery Aneurysm[J]. Journal of Kunming Medical University, 2022, 43(12): 47-52. doi: 10.12259/j.issn.2095-610X.S20221210

Citation:

Yuhao DING, Jianren WANG, Tao XIE, Liqing LIN, Zexi LIN, Weiwei ZHU, Xi’an FU, Jun PU. Risk Factors Analysis and Assessment of Ruptured Posterior Communicating Artery Aneurysm[J]. Journal of Kunming Medical University, 2022, 43(12): 47-52. doi: 10.12259/j.issn.2095-610X.S20221210

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Risk Factors Analysis and Assessment of Ruptured Posterior Communicating Artery Aneurysm

doi: 10.12259/j.issn.2095-610X.S20221210

Yuhao DING¹,
Jianren WANG¹,
Tao XIE¹,
Liqing LIN¹,
Zexi LIN¹,
Weiwei ZHU²,
Xi’an FU^{1
,
,},
Jun PU^{3
,
,}

1.
Dept. of Neurosurgery，The Affiliated Suzhou Hospital of Nanjing Medical University/Suzhou Municipal Hospital/Gusu School，Nanjing Medical University，Suzhou Jiangsu 215008
2.
Dept. of Neurosurgery，The 1st Affiliated Hospital of Soochow University，Suzhou Jiangsu 215031，China
3.
Dept. of Neurosurgery，The 2nd Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650033

Received Date: 2022-08-12
Available Online: 2022-12-05
Publish Date: 2022-12-25

Abstract

Abstract

Objective To investigate the risk factors of rupture of posterior communicating aneurysm and screen the morphologic and hemodynamic predictors. Methods A total of 78 patients with posterior communicating aneurysm diagnosed in the neurosurgery department of the Affiliated Suzhou Hospital of Nanjing Medical University, the First Affiliated Hospital of Soochow University from March 2019 to December 2021 with complete clinical data and meeting the inclusion criteria were retrospectively analyzed. 49 cases of ruptured aneurysm were in the observation group, and 29 cases of unruptured aneurysm were in the control group. Clinical data included sex, age, smoking history, history of hypertension, history of diabetes. Morphological data included aneurysm size, aspect ratio （AR）, size ratio （SR）, undulation index （UI）, nonsphericity index （NSI）, elliptic Index （EI）. The hemodynamic parameters include Wall Shear Stress （WSS）, Wall Shear Stress Gradient （WSSG） and Oscillatory Shear index （OSI）. Results There was no statistically significant difference between the two groups （P > 0.05） in age, sex, history of smoking, hypertension and diatetes. Morphological analysis showed that there were significant differences in maximum diameter, SR, UI and NSI between two groups （P < 0.05）. There were no significant differences in AR, NSI and EI （P > 0.05）. Morphological analysis showed that WSS （Pa） was significantly different between the two groups （P < 0.05）, WSSG （Pa/mm） and OSI had no significant difference （P > 0.05）. Conclusion Aneurysm size and irregular wall shape are closely related to aneurysm rupture. Low WSS may be an independent risk factor for posterior communicating aneurysm rupture.
- Intracranial aneurysm,
- Risk factors,
- Epidemiology,
- Hemodynamics

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References(17)

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