Risk Factors Analysis and Assessment of Ruptured Posterior Communicating Artery Aneurysm

Yuhao DING; Jianren WANG; Tao XIE; Liqing LIN; Zexi LIN; Weiwei ZHU; Xi’an FU; Jun PU

doi:10.12259/j.issn.2095-610X.S20221210

Volume 43 Issue 12

Dec. 2022

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Yuhao DING, Jianren WANG, Tao XIE, Liqing LIN, Zexi LIN, Weiwei ZHU, Xi’an FU, Jun PU. Risk Factors Analysis and Assessment of Ruptured Posterior Communicating Artery Aneurysm[J]. Journal of Kunming Medical University, 2022, 43(12): 47-52. doi: 10.12259/j.issn.2095-610X.S20221210

Citation:

Yuhao DING, Jianren WANG, Tao XIE, Liqing LIN, Zexi LIN, Weiwei ZHU, Xi’an FU, Jun PU. Risk Factors Analysis and Assessment of Ruptured Posterior Communicating Artery Aneurysm[J]. Journal of Kunming Medical University, 2022, 43(12): 47-52. doi: 10.12259/j.issn.2095-610X.S20221210

Citation:

Yuhao DING, Jianren WANG, Tao XIE, Liqing LIN, Zexi LIN, Weiwei ZHU, Xi’an FU, Jun PU. Risk Factors Analysis and Assessment of Ruptured Posterior Communicating Artery Aneurysm[J]. Journal of Kunming Medical University, 2022, 43(12): 47-52. doi: 10.12259/j.issn.2095-610X.S20221210

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Risk Factors Analysis and Assessment of Ruptured Posterior Communicating Artery Aneurysm

doi: 10.12259/j.issn.2095-610X.S20221210

Yuhao DING¹,
Jianren WANG¹,
Tao XIE¹,
Liqing LIN¹,
Zexi LIN¹,
Weiwei ZHU²,
Xi’an FU^{1
,
,},
Jun PU^{3
,
,}

1.
Dept. of Neurosurgery，The Affiliated Suzhou Hospital of Nanjing Medical University/Suzhou Municipal Hospital/Gusu School，Nanjing Medical University，Suzhou Jiangsu 215008
2.
Dept. of Neurosurgery，The 1st Affiliated Hospital of Soochow University，Suzhou Jiangsu 215031，China
3.
Dept. of Neurosurgery，The 2nd Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650033

Received Date: 2022-08-12
Available Online: 2022-12-05
Publish Date: 2022-12-25

Abstract

Abstract

Objective To investigate the risk factors of rupture of posterior communicating aneurysm and screen the morphologic and hemodynamic predictors. Methods A total of 78 patients with posterior communicating aneurysm diagnosed in the neurosurgery department of the Affiliated Suzhou Hospital of Nanjing Medical University, the First Affiliated Hospital of Soochow University from March 2019 to December 2021 with complete clinical data and meeting the inclusion criteria were retrospectively analyzed. 49 cases of ruptured aneurysm were in the observation group, and 29 cases of unruptured aneurysm were in the control group. Clinical data included sex, age, smoking history, history of hypertension, history of diabetes. Morphological data included aneurysm size, aspect ratio （AR）, size ratio （SR）, undulation index （UI）, nonsphericity index （NSI）, elliptic Index （EI）. The hemodynamic parameters include Wall Shear Stress （WSS）, Wall Shear Stress Gradient （WSSG） and Oscillatory Shear index （OSI）. Results There was no statistically significant difference between the two groups （P > 0.05） in age, sex, history of smoking, hypertension and diatetes. Morphological analysis showed that there were significant differences in maximum diameter, SR, UI and NSI between two groups （P < 0.05）. There were no significant differences in AR, NSI and EI （P > 0.05）. Morphological analysis showed that WSS （Pa） was significantly different between the two groups （P < 0.05）, WSSG （Pa/mm） and OSI had no significant difference （P > 0.05）. Conclusion Aneurysm size and irregular wall shape are closely related to aneurysm rupture. Low WSS may be an independent risk factor for posterior communicating aneurysm rupture.
- Intracranial aneurysm,
- Risk factors,
- Epidemiology,
- Hemodynamics

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References(17)

References

[1]	丁煜昊,谢涛,王剑刃,等. 颅内未破裂动脉瘤破裂风险因素研究进展[J]. 国际外科学杂志,2021,48(10):700-705. doi: 10.3760/cma.j.cn115396-20210904-00346
[2]	ThomPson B G,Brown R D,Aminhanjani S,et al. Guidelines for the management of Patients with unruPtured intracranial aneurysms:A guideline for healthcare Professionals from the American Heart Association/American Stroke Association[J]. Stroke; A Journal of Cerebral Circulation,2015,46(8):2368. doi: 10.1161/STR.0000000000000070
[3]	Etminan N,Brown R D Jr,Beseoglu K,et al. The unruPtured intracranial aneurysm treatment score:A multidisciPlinary consensus[J]. Neurology,2015,85(10):881-889. doi: 10.1212/WNL.0000000000001891
[4]	Zhang J,Can A,Lai P M R,et al. Age and morphology of posterior communicating artery aneurysms[J]. Sci ReP,2020,10(1):11545. doi: 10.1038/s41598-020-68276-9
[5]	Chen S,Li C,Karmonik C,et al. Performance of rupture-related morphological parameters in posterior communicating artery aneurysms with fetal-type variant[J]. Folia Morphol (Warsz),2021.
[6]	中华医学会神经病学分会,中华医学会神经病学分会脑血管病学组,中华医学会神经病学分会神经血管介入协作组. 中国蛛网膜下腔出血诊治指南2019[J]. 中华神经科杂志,2019,52(12):16.
[7]	Hosmann A,Klenk S,Wang W T,et al. Endogenous arterial blood pressure increase after aneurysmal subarachnoid hemorrhage[J]. Clin Neurol Neurosurg,2020,190:105639.
[8]	Liu Q,Jiang P,Wu J,et al. Intracranial aneurysm ruPture score may cor-relate to the risk of rebleeding before treatment of ruPtured intracranial aneurysm-s[J]. Neurol Sci.,2019,40(8):1683-1693. doi: 10.1007/s10072-019-03916-1
[9]	Juchler N,Schilling S,Bijlenga P,et al. Shape irregularity of the intracranial aneurysm lumen exhibits diagnostic value[J]. Acta Neurochir (Wien),2020,162(9):2261-2270. doi: 10.1007/s00701-020-04428-0
[10]	Jirjees S,Htun Z M,Aldawudi I,et al. Role of morphological and hemodynamic factors in predicting intracranial aneurysm rupture:A Review[J]. Cureus,2020,12(7):e9178.
[11]	Baek H,Jayaraman M V,Karniadakis G E. Wall shear stress and pressure distribution on aneurysms and infundibulae in the posterior communicating artery bifurcation[J]. Annals of Biomedical Engineering,2009,7(12):2469-2487.
[12]	Liu Q,Zhang Y,Yang J,et al. The relationship of morphological-hemodynamic characteristics,inflammation,and remodeling of aneurysm wall in unruPtured intracranial aneurysms[J]. Translational Stroke Research,2022,13(1):88-99. doi: 10.1007/s12975-021-00917-1
[13]	Ishida F,Tsuji M,Tanioka S,et al. Computational fluid dynamics for cerebral aneurysms in clinical settings[J]. Acta Neurochir Suppl,2021,132:27-32.
[14]	Uchiyama Y,Fujimura S,Takao H,et al. Role of patient-specific blood properties in computational fluid dynamics simulation of flow diverter deployed cerebral aneurysms[J]. Technol Health Care,2022,30(4):839-850. doi: 10.3233/THC-213216
[15]	Krylov V,Grigoryeva E,Dolotova D,et al. CFD Modelling of local hemodynamics in intracranial aneurysms harboring arterial branches[J]. Stud Health Technol Inform,2017,238:64-67.
[16]	Russin J,Babiker H,Ryan J,et al. Computational fluid dynamics to evaluate the management of a giant internal carotid artery aneurysm[J]. World Neurosurg,2015,83(6):1057-65. doi: 10.1016/j.wneu.2014.12.038
[17]	Busch A,Hartmann E,Grimm C,et al. Heterogeneous histomorphology,yet homogeneous vascular smooth muscle cell dedifferentiation,characterize human aneurysm disease[J]. J Vasc Surg,2017,66(5):1553-1564.e6. doi: 10.1016/j.jvs.2016.07.129

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