Volume 43 Issue 12
Dec.  2022
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Article Navigation >  Journal of Kunming Medical University  > 2022  >  43(12): 53-57
Zexing YANG, Ya WEN, Cunmei SU, Huawei WANG, Meng RAO, Yuhang ZHENG, Limei HE. Comparison the Clinical Outcomes of Progestin-Primed Ovarian Stimulation during Follicular Period and Mild-stimulation in Patients with Diminished Ovarian Reserve[J]. Journal of Kunming Medical University, 2022, 43(12): 53-57. doi: 10.12259/j.issn.2095-610X.S20221211
Citation: Zexing YANG, Ya WEN, Cunmei SU, Huawei WANG, Meng RAO, Yuhang ZHENG, Limei HE. Comparison the Clinical Outcomes of Progestin-Primed Ovarian Stimulation during Follicular Period and Mild-stimulation in Patients with Diminished Ovarian Reserve[J]. Journal of Kunming Medical University, 2022, 43(12): 53-57. doi: 10.12259/j.issn.2095-610X.S20221211
shu

Comparison the Clinical Outcomes of Progestin-Primed Ovarian Stimulation during Follicular Period and Mild-stimulation in Patients with Diminished Ovarian Reserve

doi: 10.12259/j.issn.2095-610X.S20221211
  • 1.

    Dept. of Reproductive Genetics，The 1st Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650032

  • 2.

    Yunnan Provincial Key Laboratory of Birth Regulation and Healthy Birth of Ethnic Minorities，Western Key Laboratory of Healthy Birth before Pregnancy，Kunming Yunnan 650032

  • 3.

    Wenzhou Center for Disease Control and Prevention，Wenzhou Zhejiang 325000

  • 4.

    Dept. of Epidemiology，School of Public Health, Kunming Medical University，Kunming Yunnan 650500，China

  • Received Date: 2022-05-10
  • Publish Date: 2022-12-25
    Abstract
  •   Objective   To compare the clinical outcomes of PPOS protocal and mild-stimulation protocal in patients with diminished ovarian reserve function during assisted reproduction and pregnancy.   Methods   Patients with DOR who underwent the first and second generation of test-tube babies（IVF/ICSI） in the First Affiliated Hospital of Kunming Medical University from April 2021 to April 2022 were retrospectively analyzed. A total of 294 cycles were included and divided into 2 groups（group A: PPOS group, group B: mild-stimulation group）. The medication, embryo status and pregnancy outcomes were compared between the two groups.   Results   Initiation dose of Gn, total Gn dose, HCG dose on trigger day in group A were significantly higher than those in group B（P < 0.05）; LH on HCG day in group A was lower than that in group B（ P < 0.05）. The number of eggs, embryos and high quality embryos in group A were higher than those in group B（ P < 0.05）.   Conclusion   The clinical outcomes of the PPOS group were better than the mild-stimulation group.
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    • References(19)
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