Research Progress of Cytoreductive Treatment for Metastatic Prostate Cancer

Longguo DAI; Yu BAI

doi:10.12259/j.issn.2095-610X.S20230103

Volume 44 Issue 1

Jan. 2023

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Longguo DAI, Yu BAI. Research Progress of Cytoreductive Treatment for Metastatic Prostate Cancer[J]. Journal of Kunming Medical University, 2023, 44(1): 135-139. doi: 10.12259/j.issn.2095-610X.S20230103

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Longguo DAI, Yu BAI. Research Progress of Cytoreductive Treatment for Metastatic Prostate Cancer[J]. Journal of Kunming Medical University, 2023, 44(1): 135-139. doi: 10.12259/j.issn.2095-610X.S20230103

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Research Progress of Cytoreductive Treatment for Metastatic Prostate Cancer

doi: 10.12259/j.issn.2095-610X.S20230103

Longguo DAI,
Yu BAI^,

Dept. of Urinary Surgery，Yunnan Tumor Hospital，Kunming Yunnan 650118，China

Received Date: 2022-11-15
Available Online: 2023-01-18
Publish Date: 2023-01-18

Abstract

Abstract

Metastatic prostate cancer （mPCa） will progress to castrate-resistant state after a period of androgen-deprivation therapy （ADT） alone. Therefore, increasing focus is being placed on the additional survival benefits that could potentially be achieved with local cytoreductive and/or metastasis-directed therapies （MDT）. Local treatment of the primary tumour with the established modalities of radiotherapy and radical prostatectomy has been explored in this context, and the use of novel minimally invasive ablative therapies has been proposed. In addition, evidence of the potential clinical benefits of MDT with ionizing radiation （primarily stereotactic ablative radiotherapy） is accumulating. This aticle summarizes the current evidence base for a cytoreductive strategy in patients with mPCa.
- Metastatic prostate cancer,
- Cytoreductive treatment,
- Ablative therapies,
- Radiotherapy,
- Prostatectomy

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References(26)

References

[1]	Siegel R L,Miller K D,Fuchs H E,et al. Cancer statistics,2022[J]. CA Cancer J Clin,2022,72(1):7-33. doi: 10.3322/caac.21708
[2]	Wang L,Paller C J,Hong H,et al. Comparison of systemic treatments for metastatic castration-sensitive prostate cancer: A systematic review and network meta-analysis[J]. JAMA Oncol,2021,7(3):412-420. doi: 10.1001/jamaoncol.2020.6973
[3]	Cheng Q,Butler W,Zhou Y,et al. Pre-existing castration-resistant prostate cancer-like cells in primary prostate cancer promote resistance to hormonal therapy[J]. Eur Urol,2022,81(5):446-455. doi: 10.1016/j.eururo.2021.12.039
[4]	Ranasinghe W,Chapin B F,Kim I Y,et al. The cytoreductive prostatectomy in metastatic prostate cancer: what the individual trials are hoping to answer[J]. BJU Int,2020,125(6):792-800. doi: 10.1111/bju.15055
[5]	Püllen L,Sprave T,Hadaschik B,et al. [Local and metastasis-directed therapy for oligometastatic prostate cancer][J]. Aktuelle Urol,2021,52(2):149-154. doi: 10.1055/a-1328-9975
[6]	Boevé L M S,Hulshof M,Vis A N,et al. Effect on survival of androgen deprivation therapy alone compared to androgen deprivation therapy combined with concurrent radiation therapy to the prostate in patients with primary bone metastatic prostate cancer in a prospective randomised clinical trial: Data from the HORRAD trial[J]. Eur Urol,2019,75(3):410-418. doi: 10.1016/j.eururo.2018.09.008
[7]	Cho Y,Chang J S,Rha K H,et al. Does radiotherapy for the primary tumor benefit prostate cancer patients with distant metastasis at initial diagnosis?[J]. PLoS One,2016,11(1):e0147191. doi: 10.1371/journal.pone.0147191
[8]	Culp S H,Schellhammer P F,Williams M B. Might men diagnosed with metastatic prostate cancer benefit from definitive treatment of the primary tumor? A SEER-based study[J]. Eur Urol,2014,65(6):1058-1066. doi: 10.1016/j.eururo.2013.11.012
[9]	Parker C C,James N D,Brawley C D,et al. Radiotherapy to the primary tumour for newly diagnosed,metastatic prostate cancer (STAMPEDE): A randomised controlled phase 3 trial[J]. Lancet,2018,392(10162):2353-2366. doi: 10.1016/S0140-6736(18)32486-3
[10]	Rusthoven C G,Jones B L,Flaig T W,et al. Improved survival with prostate radiation in addition to androgen deprivation therapy for men with newly diagnosed metastatic prostate cancer[J]. J Clin Oncol,2016,34(24):2835-2842. doi: 10.1200/JCO.2016.67.4788
[11]	Gratzke C,Engel J,Stief C G. Role of radical prostatectomy in metastatic prostate cancer: Data from the munich cancer registry[J]. Eur Urol,2014,66(3):602-603. doi: 10.1016/j.eururo.2014.04.009
[12]	Sooriakumaran P,Karnes J,Stief C,et al. A multi-institutional analysis of perioperative outcomes in 106 men who underwent radical prostatectomy for distant metastatic prostate cancer at presentation[J]. Eur Urol,2016,69(5):788-794. doi: 10.1016/j.eururo.2015.05.023
[13]	Jang W S,Kim M S,Jeong W S,et al. Does robot-assisted radical prostatectomy benefit patients with prostate cancer and bone oligometastases?[J]. BJU Int,2018,121(2):225-231. doi: 10.1111/bju.13992
[14]	Shemshaki H,Al-mamari S A,Geelani I A,et al. Cytoreductive radical prostatectomy versus systemic therapy and radiation therapy in metastatic prostate cancer: A systematic review and meta-analysis[J]. Urologia,2022,89(1):16-30. doi: 10.1177/03915603211036631
[15]	Lumen N,De Bleser E,Buelens S,et al. The role of cytoreductive radical prostatectomy in the treatment of newly diagnosed low-volume metastatic prostate cancer. Results from the local treatment of metastatic prostate cancer (LoMP) registry[J]. Eur Urol Open Sci,2021,29(6):68-76.
[16]	Heidenreich A,Pfister D,Porres D. Cytoreductive radical prostatectomy in patients with prostate cancer and low volume skeletal metastases: Results of a feasibility and case-control study[J]. J Urol,2015,193(3):832-838. doi: 10.1016/j.juro.2014.09.089
[17]	Shah T T,Peters M,Eldred-evans D,et al. Early-medium-term outcomes of primary focal cryotherapy to treat nonmetastatic clinically significant prostate cancer from a prospective multicentre registry[J]. Eur Urol,2019,76(1):98-105. doi: 10.1016/j.eururo.2018.12.030
[18]	Morkos J,Porosnicu Rodriguez K A,Zhou A,et al. Percutaneous cryoablation for stage 1 renal cell carcinoma: Outcomes from a 10-year prospective study and comparison with matched cohorts from the national cancer database[J]. Radiology,2020,296(2):452-459. doi: 10.1148/radiol.2020192325
[19]	Sheng M X,Wan L L,Liu C M,et al. Cytoreductive cryosurgery in patients with bone metastatic prostate cancer: A retrospective analysis[J]. Kaohsiung J Med Sci,2017,33(12):609-615. doi: 10.1016/j.kjms.2017.07.002
[20]	Reddy D,Peters M,Shah T T,et al. Cancer control outcomes following focal therapy using high-intensity focused ultrasound in 1379 men with nonmetastatic prostate cancer: A multi-institute 15-year experience[J]. Eur Urol,2022,81(4):407-413. doi: 10.1016/j.eururo.2022.01.005
[21]	Ishihara H,Takagi T,Kondo T,et al. Prognostic impact of metastasectomy in renal cell carcinoma in the postcytokine therapy era[J]. Urol Oncol,2021,39(1):77.e17-77.e25. doi: 10.1016/j.urolonc.2020.08.011
[22]	Parker C,Nilsson S,Heinrich D,et al. Alpha emitter radium-223 and survival in metastatic prostate cancer[J]. N Engl J Med,2013,369(3):213-223. doi: 10.1056/NEJMoa1213755
[23]	Ost P,Reynders D,Decaestecker K,et al. Surveillance or metastasis-directed therapy for oligometastatic prostate cancer recurrence: A prospective,randomized,multicenter phase II trial[J]. J Clin Oncol,2018,36(5):446-453. doi: 10.1200/JCO.2017.75.4853
[24]	O'shaughnessy M J,Mcbride S M,Vargas H A,et al. A pilot study of a multimodal treatment paradigm to accelerate drug evaluations in early-stage metastatic prostate cancer[J]. Urology,2017,102(4):164-172.
[25]	Radwan N,Phillips R,Ross A,et al. A phase II randomized trial of observation versus stereotactic ablative radiation for oligometastatic prostate cancer (ORIOLE)[J]. BMC Cancer,2017,17(1):453. doi: 10.1186/s12885-017-3455-6
[26]	Sartor O,De Bono J,Chi K N,et al. Lutetium-177-PSMA-617 for metastatic castration-resistant prostate cancer[J]. N Engl J Med,2021,385(12):1091-1103. doi: 10.1056/NEJMoa2107322

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