Effect of Different Intestinal Surgical Methods on Prognosis of Patients with Intestinal Invasive Epithelial Ovarian Cancer

Yaping JIANG; Hongying YANG; Haohan WANG; Xianling Ning; Xielan YANG

doi:10.12259/j.issn.2095-610X.S20230109

Volume 44 Issue 1

Jan. 2023

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Article Navigation > Journal of Kunming Medical University > 2023 > 44(1): 85-90

Yaping JIANG, Hongying YANG, Haohan WANG, Xianling Ning, Xielan YANG. Effect of Different Intestinal Surgical Methods on Prognosis of Patients with Intestinal Invasive Epithelial Ovarian Cancer[J]. Journal of Kunming Medical University, 2023, 44(1): 85-90. doi: 10.12259/j.issn.2095-610X.S20230109

Citation:

Yaping JIANG, Hongying YANG, Haohan WANG, Xianling Ning, Xielan YANG. Effect of Different Intestinal Surgical Methods on Prognosis of Patients with Intestinal Invasive Epithelial Ovarian Cancer[J]. Journal of Kunming Medical University, 2023, 44(1): 85-90. doi: 10.12259/j.issn.2095-610X.S20230109

Citation:

Yaping JIANG, Hongying YANG, Haohan WANG, Xianling Ning, Xielan YANG. Effect of Different Intestinal Surgical Methods on Prognosis of Patients with Intestinal Invasive Epithelial Ovarian Cancer[J]. Journal of Kunming Medical University, 2023, 44(1): 85-90. doi: 10.12259/j.issn.2095-610X.S20230109

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Effect of Different Intestinal Surgical Methods on Prognosis of Patients with Intestinal Invasive Epithelial Ovarian Cancer

doi: 10.12259/j.issn.2095-610X.S20230109

Dept. of Gynecology，The 3rd Affiliated Hospital of Kunming Medical University/Yunnan Cancer Hospital，Kunming Yunnan 650118，China

Received Date: 2022-10-10
Available Online: 2022-12-23
Publish Date: 2023-01-18

Abstract

Abstract

Objective To investigate the effect of intestinal segment resection and local tumor removal on the prognosis of patients with intestinal metastatic epithelial ovarian cancer. Methods The clinical data of the patients who were admitted to Yunnan Province Tumor Hospital with advanced epithelial ovarian cancers from June 2017 to June 2021 were reviewed. All of the patients were treated by the same woman tumor expert of the Department of Gynecology and his team and the safety and feasibility of two kinds of operation methods were compared. Results Among 56 patients, 33 （58.9%） underwent the intestinal resection and anastomosis, and 23 （41.1%） underwent the intestinal tumor removal and bowel repair. There was no significant difference in satisfactory tumor reduction rate between the two groups （63.6%, 87.0%, P > 0.05）. In the median follow-up time of 24.5 months （18.75～42.75）, the recurrence rates in the enterectomy group and the tumor excision group were 57.6% and 42.4% respectively, the mortality rates were 78.8% and 82.6%, respectively, and the median relapse-free survival time were 31 months and 19 months, respectively, with no statistical significance （P > 0.05）. Operations in intestinal resection group were carried out with longer time, more difficulties, more blood loss and more blood transfusion. The incidence of postoperative complications was higher, and the difference was statistically significant （P < 0.05）. Conclusion There is no significant difference in the tumor reduction outcome and survival of patients with ovarian cancer tumor cell reduction after the intestinal resection and tumor removal, but the patients may face more complications and poorer quality of life after the intestinal resection. Therefore, during the operation, the depth of tumor invasion of the intestinal wall, the scope of intestinal invasion and the separability of the tumor should be fully assessed, so as to preserve the intestinal tract as much as possible, and to reduce the occurrence of postoperative complications.
- Epithelial ovarian cancer,
- Debulking surgery,
- Intestinal surgery,
- Prognosis

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References(18)

References

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