Quantitative Analysis of Real-time Ultrasound Elastography in Elderly Patients with Advanced Malignant Obstructive Jaundice and the Assessment of Prognostic Value of PTCD

Hong LI

doi:10.12259/j.issn.2095-610X.S20230123

Volume 44 Issue 1

Jan. 2023

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Article Navigation > Journal of Kunming Medical University > 2023 > 44(1): 122-127

Hong LI. Quantitative Analysis of Real-time Ultrasound Elastography in Elderly Patients with Advanced Malignant Obstructive Jaundice and the Assessment of Prognostic Value of PTCD[J]. Journal of Kunming Medical University, 2023, 44(1): 122-127. doi: 10.12259/j.issn.2095-610X.S20230123

Citation:

Hong LI. Quantitative Analysis of Real-time Ultrasound Elastography in Elderly Patients with Advanced Malignant Obstructive Jaundice and the Assessment of Prognostic Value of PTCD[J]. Journal of Kunming Medical University, 2023, 44(1): 122-127. doi: 10.12259/j.issn.2095-610X.S20230123

Citation:

Hong LI. Quantitative Analysis of Real-time Ultrasound Elastography in Elderly Patients with Advanced Malignant Obstructive Jaundice and the Assessment of Prognostic Value of PTCD[J]. Journal of Kunming Medical University, 2023, 44(1): 122-127. doi: 10.12259/j.issn.2095-610X.S20230123

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Quantitative Analysis of Real-time Ultrasound Elastography in Elderly Patients with Advanced Malignant Obstructive Jaundice and the Assessment of Prognostic Value of PTCD

doi: 10.12259/j.issn.2095-610X.S20230123

Hong LI

Dept. of Ultrasound，Kunming First People’s Hospital，Kunming Yunnan 650011，China

Received Date: 2022-11-08
Available Online: 2022-12-23
Publish Date: 2023-01-18

Abstract

Abstract

Objective To explore the relationship between the quantitative analysis of real-time ultrasound elastography and the prognosis of percutaneous transbiliary drainage （PTCD） in elderly patients with advanced malignant obstructive jaundice. Methods A retrospective selection of 112 elderly patients with advanced malignant obstructive jaundice who underwent PTCD treatment in Kunming First People’s Hospital between May 2017 and May 2021 were divided into poor prognosis （n = 42） and good prognosis groups （n = 70） according to their prognosis. The clinical data, quantitative real-time ultrasound elastography before PTCD （at admission） and after PTCD （1 week after surgery） between the two groups were compared so as to analyse the correlation between quantitative real-time ultrasound elastography and Child-Pugh score, the relationship between quantitative real-time ultrasound elastography after PTCD and the prognosis of PTCD in elderly patients with advanced malignant obstructive jaundice. The subject work characteristic （ROC） curve was plotted to evaluate the diagnostic value of quantitative real-time ultrasound elastography after PTCD on the prognosis of PTCD in elderly patients with advanced malignant obstructive jaundice. Results The mean strain values were lower and the percentage of blue fields was higher in the poor prognosis group compared to those of the good prognosis group for quantitative indicators of real-time ultrasound elastography after PTCD （P < 0.05）; The mean value of strain and blue field percentage were associated with Child-Pugh score （P < 0.05）; Strain mean value and blue field percentage were independent factors influencing PTCD prognosis in elderly patients with advanced malignant obstructive jaundice （P < 0.05）; The AUC for the combined diagnosis of strain mean value and blue field percentage in elderly patients with advanced malignant obstructive jaundice for PTCD prognosis was 0.862. Conclusion Real-time ultrasound elastography quantitative measurement of mean strain and percentage of blue area in elderly patients with advanced malignant obstructive jaundice are related to the liver function and prognosis. Real-time ultrasound elastography quantification after PTCD can help predict the prognosis of the disease. It is of great significance in clinical work.
- Malignant obstructive jaundice,
- Old age,
- Advanced,
- Real-time ultrasound elastography,
- PTCD,
- Prognosis

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References(21)

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