Research Progress on the Pathogenesis of Pterygium

Huawei JIANG; Xia LIU; Yan WANG; Minhui ZHANG; Weidan YIN; Liwei ZHANG

doi:10.12259/j.issn.2095-610X.S20230125

Volume 44 Issue 1

Jan. 2023

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Article Navigation > Journal of Kunming Medical University > 2023 > 44(1): 144-150

Huawei JIANG, Xia LIU, Yan WANG, Minhui ZHANG, Weidan YIN, Liwei ZHANG. Research Progress on the Pathogenesis of Pterygium[J]. Journal of Kunming Medical University, 2023, 44(1): 144-150. doi: 10.12259/j.issn.2095-610X.S20230125

Citation:

Huawei JIANG, Xia LIU, Yan WANG, Minhui ZHANG, Weidan YIN, Liwei ZHANG. Research Progress on the Pathogenesis of Pterygium[J]. Journal of Kunming Medical University, 2023, 44(1): 144-150. doi: 10.12259/j.issn.2095-610X.S20230125

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Research Progress on the Pathogenesis of Pterygium

doi: 10.12259/j.issn.2095-610X.S20230125

Dept. of Ophthalmology，The Affiliated Hospital of Yunnan University，The 2nd People’s Hospital of Yunnan，Yunnan Eye Hospital，The 4th Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650021，China

Received Date: 2022-11-19
Available Online: 2022-12-24
Publish Date: 2023-01-18

Abstract

Abstract

Pterygium is a common ocular surface disease in the population and its risk factors are mainly ultraviolet radiation. The pathogenesis mainly includes oxidative stress, phototoxicity, cell proliferation and apoptosis, extracellular matrix remodeling, inflammation and immune regulation. A variety of important proteins involved in the above mechanisms have been identified, but their regulatory signaling pathways in pterygium are still unclear and are currently considered to be the result of a combination of mechanisms, and their relatively complete pathogenesis needs further exploration. This paper aims to review the different pathogenesis of pterygium in order to better understand the occurrence and development of pterygium and seek new therapeutic targets and methods, so as to improve the surgical effect and reduce postoperative recurrence.
- Pterygium,
- Pathogenesis,
- Proliferation and apoptosis,
- Inflammation

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References(48)

References

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