Volume 44 Issue 1
Jan.  2023
Turn off MathJax
Article Contents
Fenghua LU, Zhaolin DU, Rong ZHANG. Effects of Red Light Irradiation Combined with Lower Extremity Muscle Strength Training on Lower Extremity Motor Function,TCSS Score and SOD Level in Patients with Diabetic Peripheral Neuropathy[J]. Journal of Kunming Medical University, 2023, 44(1): 163-167. doi: 10.12259/j.issn.2095-610X.S20230129
Citation: Fenghua LU, Zhaolin DU, Rong ZHANG. Effects of Red Light Irradiation Combined with Lower Extremity Muscle Strength Training on Lower Extremity Motor Function,TCSS Score and SOD Level in Patients with Diabetic Peripheral Neuropathy[J]. Journal of Kunming Medical University, 2023, 44(1): 163-167. doi: 10.12259/j.issn.2095-610X.S20230129

Effects of Red Light Irradiation Combined with Lower Extremity Muscle Strength Training on Lower Extremity Motor Function,TCSS Score and SOD Level in Patients with Diabetic Peripheral Neuropathy

doi: 10.12259/j.issn.2095-610X.S20230129
  • Received Date: 2022-11-09
    Available Online: 2023-01-18
  • Publish Date: 2023-01-18
  •   Objective  To analyze the effect of red light irradiation combined with lower extremity muscle strength training on lower extremity motor function, Toronto Clinical Scoring System (TCSS) score and superoxide dismutase (SOD) level in patients with diabetic peripheral neuropathy (DPN).   Methods  A total of 100 DPN patients admitted to our hospital from January 2020 to January 2022 were selected and divided into two groups according to the random number table method. 50 cases in the observation group received red light irradiation combined with lower limb muscle strength training, and 50 cases in the control group received the lower body strength training only. The clinical efficacy, lower extremity FMA score, TCSS score, SOD level and nerve conduction velocity data of the two groups were statistically analyzed.   Results  The total clinical effective rate of the observation group was 88.00%, which was significantly higher than that of the control group (66.00%), and the difference was statistically significant (χ2 = 4.312, P = 0.038, P < 0.001), the TCSS score was significantly decreased (P < 0.001), and there were statistically significant differences in the FMA score, TCSS score and SOD level between the two groups after the intervention (P < 0.01); The motor nerve and sensory nerve conduction velocity in the observation group after the intervention were significantly faster than those in the control group, and the difference was statistically significant (P < 0.05).   Conclusion  Red light irradiation combined with lower extremity muscle strength training can effectively improve the neuropathy state of DPN patients, reduce oxidative stress, increase nerve conduction velocity, and then enhance the lower extremity motor function.
  • loading
  • [1]
    余玲,张薇,付文涛. 木丹颗粒联合硫辛酸注射液对糖尿病周围神经病变患者TSS评分及SOD、Hcy血清水平干预的影响[J]. 四川生理科学杂志,2022,44(1):30-33. doi: 10.3969/j.issn.1671-3885.2022.1.scslkxzz202201008
    [2]
    Lai Z Q,Pang H B,Hu X Y,et al. Effects of intrinsic-foot-muscle exercise combined with the lower extremity resistance training on postural stability in older adults with fall risk: Study protocol for a randomised controlled trial[J]. Nature Review,2021,22(587):2-13.
    [3]
    张颖,简娇敏,娄晓丽,等. 糖尿病周围神经病变患者多伦多神经症状评分与炎症状态的相关性研究[J]. 中国糖尿病杂志,2019,27(5):352-356. doi: 10.3969/j.issn.1006-6187.2019.05.007
    [4]
    杨丽梅,贾荣梅,高倩,等. 木丹颗粒联合甲钴胺对2型糖尿病周围神经病变气虚络阻证的疗效及对神经电生理和氧化应激指标的影响[J]. 临床和实验医学杂志,2020,19(2):181-184. doi: 10.3969/j.issn.1671-4695.2020.02.019
    [5]
    阮东英. 黄芪泡服联合中药熏洗对糖尿病下肢周围神经病变患者血糖控制及TCSS评分的影响[J]. 中国疗养医学,2020,29(11):1222-1223.
    [6]
    周思梦,詹蔷薇. 复方丹参滴丸联合丹参川芎嗪注射液对糖尿病周围神经病变中的应用及对MDNS和TCSS评分、血液流变学指标的影响分析[J]. 中国血液流变学杂志,2021,31(3):337-339. doi: 10.3969/j.issn.1009-881X.2021.03.009
    [7]
    顾平,冉娟娟,崔羽,等. 贝前列素钠联合复方丹参滴丸在治疗糖尿病周围神经病变中的效果观察[J]. 湖南师范大学学报(医学版),2020,17(1):18-21. doi: 10.3969/j.issn.1673-016X.2020.01.006
    [8]
    Liao C D,Wu R T,Tsauo J W,et al. Effects of protein supplementation combined with exercise training on muscle mass and function in older adults with lower-extremity osteoarthritis: A systematic review and meta-analysis of randomized trials[J]. Nutrients,2020,12(8):1-20.
    [9]
    Inagaki Y,Ogawa Y,Sato Y,et al. Comparison of the upper and lower extremity and trunk muscle masses between children with down syndrome and children with typical development[J]. Taylor & Francis,2022,122(21):41-53.
    [10]
    中华医学会糖尿病学分会. 中国2型糖尿病防治指南(2017年版)[J]. 中华糖尿病杂志,2018,10(1):4-67. doi: 10.3760/cma.j.issn.1674-5809.2018.01.003
    [11]
    康锦芬,李靖云,黄文森,等. 贝前列素钠联合硫辛酸对糖尿病周围神经病变患者TCSS 评分、MDNS 评分及神经传导速度的影响[J]. 川北医学院学报,2019,34(2):190-193. doi: 10.3969/j.issn.1005-3697.2019.02.07
    [12]
    胡一俊. 依帕司他联合ɑ-硫辛酸治疗老年糖尿病周围神经病变的效果及对氧化应激反应的影响[J]. 新乡医学院学报,2019,36(4):327-330.
    [13]
    Asano S,Hamaoka R,Jonai S,et al. Acetic acid detection in photovoltaic modules during ultraviolet irradiation and damp-heat combined tests[J]. Japan J App Phys,2022,61(6):66501. doi: 10.35848/1347-4065/ac5734
    [14]
    杨彩霞,何笛,陈坤. 丁苯酞软胶囊联合依帕司他对2型糖尿病周围神经病变的疗效及对患者氧化应激水平的影响[J]. 中国合理用药探索,2020,17(8):58-61.
    [15]
    Selvarajah D,Kar D,Khunti K,et al. Diabetic peripheral neuropathy: Advances in diagnosis and strategies for screening and early intervention[J]. Lancet Diabetes Endo,2019,7(12):938-948. doi: 10.1016/S2213-8587(19)30081-6
    [16]
    周海平,周君,杨涛,等. 糖尿病周围神经病变的发病机制及相关生物学标志物研究进展[J]. 中华糖尿病杂志,2021,13(2):187-190.
    [17]
    Yu J L,Tolley P D,Kneib C,et al. Current concepts in microsurgical soft tissue reconstruction of lower extremity trauma in a single-vessel extremity[J]. Plastic & Aesth Res,2022,9(5):56-66.
    [18]
    Orlando G,Balducci S,Boulton A J M,et al. Neuromuscular dysfunction and exercise training in people with diabetic peripheral neuropathy: A narrative review[J]. Diabet Res & Clin Pract,2022,1(183):109183.
    [19]
    Inoue T,Charlie Y,Imai S,et al. Efficiency of novel shielding curtains combined with pulsed irradiation for reducing radiation exposure in an operating room: Human renal collecting system phantom study[J]. Taylor & Francis,2022,19(31):501-517.
    [20]
    王俊. 红光治疗仪照射联合下肢力量训练在糖尿病周围神经病变患者中的应用效果[J]. 医疗装备,2021,34(24):187-188. doi: 10.3969/j.issn.1002-2376.2021.24.098
    [21]
    杨晓荣,刘连勇,杨玲,等. 抗阻力运动对2型糖尿病周围神经病变的影响[J]. 中南大学学报(医学版),2020,45(10):1185-1192. doi: 10.11817/j.issn.1672-7347.2020.190505
  • Relative Articles

    [1] Ying TAN, Haiyan QIN, Xiang SUN, Yanyi SU, Yingbao WANG. Propofol Regulates MPP+-induced Mitochondrial Oxidative Stress and Apoptosis in SH-SY5Y Cells. Journal of Kunming Medical University, 2024, 45(3): 35-41.  doi: 10.12259/j.issn.2095-610X.S20240305
    [2] Yidan FU, Wenting CHEN, Xiaoyang SU, Yan ZHAO, Danfeng LAN, Qiuping YANG. Role of Mertk-mediated NF-κb Pathway in Inflammatory Response of Schwann Cells. Journal of Kunming Medical University, 2023, 44(12): 20-24.  doi: 10.12259/j.issn.2095-610X.S20231203
    [3] Fan ZHANG, Weichang GUO, Hong TAN, Hejia YIN, Luping PENG, Yan ZHAO, Huifang LI. Development and Validation of Risk Predicting Model for Severe Diabetic Peripheral Neuropathy Based on Glucose Variability Parameters. Journal of Kunming Medical University, 2023, 44(5): 53-59.  doi: 10.12259/j.issn.2095-610X.S20230526
    [4] Li DONG, Shibo SUN, Shuguang SUN. Advances on Scutellarin Anti-Oxidative Stress Mechanism in the Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases. Journal of Kunming Medical University, 2022, 43(4): 146-151.  doi: 10.12259/j.issn.2095-610X.S20220423
    [5] Xuan XU, Moxian CHEN, Guanglei LIU, Xiao XU, Changliang LUO, Ya ZHOU. Correlation between Attention and Motor Function in Children with Spastic Hemiplegia. Journal of Kunming Medical University, 2022, 43(3): 44-49.  doi: 10.12259/j.issn.2095-610X.S20220319
    [6] Guo-qiang XUE, Xin-xin WEI, Na YAO, Wen-hua ZHAO. Metformin Protects Type II Diabetic Kidneys by Regulating PARP-1 Activity. Journal of Kunming Medical University, 2021, 42(6): 29-37.  doi: 10.12259/j.issn.2095-610X.S20210632
    [7] Si-jin HE, Xiao-xia CHEN, Kai-xuan LUO, Li-hua GU, Zhi-juan HE, Jian-ying ZHOU. Influence of Mirror Therapy Combined with Occupational Therapy on Upper Limb Motor Function and ADL in Hemiplegia after Stroke. Journal of Kunming Medical University, 2021, 42(6): 129-133.  doi: 10.12259/j.issn.2095-610X.S20210611
    [8] Xiao-rui YANG, Qian XIANG, Ya QIU, Yan LUAN, Xian ZHANG, Yan GUO. Correlation between Serum 25-hydroxyvitamin D and Peripheral Neuropathy in Type 2 Diabetes. Journal of Kunming Medical University, 2021, 42(7): 88-93.  doi: 10.12259/j.issn.2095-610X.S20210714
    [9] Guo An Li , Fu Chang Bi , Yang Xiao Qing , Zhang Shi Mei , Shi Zheng Juan . . Journal of Kunming Medical University, 2019, 40(12): 97-102.
    [10] Zeng Qing Ju , Li Hui , Wang Jin Wen . . Journal of Kunming Medical University, 2019, 40(10): 62-66.
    [11] Dai Qing Li , Sun Gui Hu , Yan Bin , Guo Tao , Dai Qing Yuan . Establishment of Oxidative Stress Model by Inducing Human Umbilical Vein Endothelial Cells Using Hydrogen Peroxide. Journal of Kunming Medical University, 2018, 39(04): 34-39.
    [12] Zeng Bai Rui . . Journal of Kunming Medical University,
    [13] Bian Hai Xia . . Journal of Kunming Medical University,
    [14] Liu Song . . Journal of Kunming Medical University,
    [15] Ding Yan Jie . . Journal of Kunming Medical University,
    [16] Zhang Yuan . . Journal of Kunming Medical University,
    [17] Li Ruo Nan . . Journal of Kunming Medical University,
    [18] Yan Qing Feng . Effects of Luteolin on Isolated Heart Function and Oxidative Stress Reaction after Hypothermic Preservation. Journal of Kunming Medical University,
    [19] . Sanchinoside for Diabetic Peripheral Neuropathy:A Meta Analysis. Journal of Kunming Medical University,
    [20] Gui Li . . Journal of Kunming Medical University,
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(4)

    Article Metrics

    Article views (3695) PDF downloads(6) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return