Quantitative Analysis of Real-time Ultrasound Elastography in Elderly Patients with Advanced Malignant Obstructive Jaundice in Assessing the Prognosis of PTCD

Hong LI

doi:10.12259/j.issn.2095-610X.S20230206

Volume 44 Issue 2

Feb. 2023

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Hong LI. Quantitative Analysis of Real-time Ultrasound Elastography in Elderly Patients with Advanced Malignant Obstructive Jaundice in Assessing the Prognosis of PTCD[J]. Journal of Kunming Medical University, 2023, 44(2): 150-155. doi: 10.12259/j.issn.2095-610X.S20230206

Citation:

Hong LI. Quantitative Analysis of Real-time Ultrasound Elastography in Elderly Patients with Advanced Malignant Obstructive Jaundice in Assessing the Prognosis of PTCD[J]. Journal of Kunming Medical University, 2023, 44(2): 150-155. doi: 10.12259/j.issn.2095-610X.S20230206

Citation:

Hong LI. Quantitative Analysis of Real-time Ultrasound Elastography in Elderly Patients with Advanced Malignant Obstructive Jaundice in Assessing the Prognosis of PTCD[J]. Journal of Kunming Medical University, 2023, 44(2): 150-155. doi: 10.12259/j.issn.2095-610X.S20230206

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Quantitative Analysis of Real-time Ultrasound Elastography in Elderly Patients with Advanced Malignant Obstructive Jaundice in Assessing the Prognosis of PTCD

doi: 10.12259/j.issn.2095-610X.S20230206

Hong LI

Dept. of Ultrasound The First People’s Hospital of Kunming，Kunming Yunnan 650011，China

Received Date: 2022-12-11
Available Online: 2023-01-31
Publish Date: 2023-02-25

Abstract

Abstract

Objective To explore the relationship between quantitative analysis of real-time ultrasound elastography and the prognosis of percutaneous transbiliary drainage （PTCD） in elderly patients with advanced malignant obstructive jaundice. Methods Retrospectively selected 112 elderly patients with advanced malignant obstructive jaundice who underwent PTCD treatment in our hospital between May 2017 and May 2021 were divided into poor prognosis （n = 42） and good prognosis groups （n = 70） according to their prognosis. We compared the clinical data of the two groups, the quantitative indexes of real-time ultrasound elastography before and after PTCD, analyzed the correlation between the quantitative indexes of real-time ultrasound elastography and Child-Pugh score, the quantitative indexes of real-time ultrasound elastography after PTCD and the prognosis of PTCD in elderly patients with advanced malignant obstructive jaundice, and drew the receiver operating characteristic （ROC） curve, and evaluated the value of real-time ultrasound elastography quantitative indicators for the prognosis of elderly patients with advanced malignant obstructive jaundice after PTCD. Results There were statistically significant differences in the site of obstruction, Child-Pugh score, and total bilirubin level between the two groups （P < 0.05）. The mean value of strain of real-time postoperative ultrasound elastography quantitative index of PTCD in the poor prognosis group was lower than that in the good prognosis group, and the percentage of blue field was higher than that in the good prognosis group （P < 0.05）. The mean value of strain and blue field percentage were associated with Child-Pugh score （P < 0.05）. Strain mean value and blue field percentage were independent factors influencing PTCD prognosis in elderly patients with advanced malignant obstructive jaundice （P < 0.05）.The AUC for the combined diagnosis of strain mean value and blue field percentage in elderly patients with advanced malignant obstructive jaundice for PTCD prognosis was 0.862. Conclusions Real-time ultrasound elastography quantitative measurement of mean strain and percentage of blue area in elderly patients with advanced malignant obstructive jaundice are related to the liver function and prognosis. Real-time ultrasound elastography quantification after PTCD can help predict the prognosis of the disease. It is of great significance in clinical work.
- Malignant obstructive jaundice,
- Old age,
- Advanced,
- Real-time ultrasound elastography,
- PTCD,
- Prognosis

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References(21)

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