Research Overview of HPA Axis in Depression

Lei YU; Wenzhi WU; Yunqiao ZHANG; Xu YOU; Yong ZENG

doi:10.12259/j.issn.2095-610X.S20230222

Volume 44 Issue 2

Feb. 2023

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Lei YU, Wenzhi WU, Yunqiao ZHANG, Xu YOU, Yong ZENG. Research Overview of HPA Axis in Depression[J]. Journal of Kunming Medical University, 2023, 44(2): 166-171. doi: 10.12259/j.issn.2095-610X.S20230222

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Lei YU, Wenzhi WU, Yunqiao ZHANG, Xu YOU, Yong ZENG. Research Overview of HPA Axis in Depression[J]. Journal of Kunming Medical University, 2023, 44(2): 166-171. doi: 10.12259/j.issn.2095-610X.S20230222

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Research Overview of HPA Axis in Depression

doi: 10.12259/j.issn.2095-610X.S20230222

1.
The 2nd Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650101
2.
The Second People's Hospital of Honghe Prefecture，Honghe Yunnan 651400，China

Received Date: 2022-12-06
Publish Date: 2023-02-25

Abstract

Abstract

The main clinical feature of depression is marked and persistent low mood, and its high incidence and high disability have brought a heavy burden to individuals, families and society. Recent studies on neuroendocrine in patients with depression have shown that disorders of the hypothalamic-pituitary-adrenocortical axis （HPA axis） plays an important role in the pathogenesis of depression. This article reviews the research progress of HPA axis and depression in recent years, in order to provide new ideas and reference value for the diagnosis and treatment of depression.
- Depression,
- Hypothalamic-pituitary-adrenal axis,
- Corticotropin-releasing hormone,
- Adrenocorticotrophic hormone,
- Cortisol

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References(51)

References

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