Analysis of HPV Detection in 18 449 Hospital Patients in Kunming and HPV Vaccination Recommendations

Jiawei DING; Jia WANG; Shu YANG; Sulian CHEN; Jing LI

doi:10.12259/j.issn.2095-610X.S20230302

Volume 44 Issue 3

Mar. 2023

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Article Navigation > Journal of Kunming Medical University > 2023 > 44(3): 81-86

Jiawei DING, Jia WANG, Shu YANG, Sulian CHEN, Jing LI. Analysis of HPV Detection in 18 449 Hospital Patients in Kunming and HPV Vaccination Recommendations[J]. Journal of Kunming Medical University, 2023, 44(3): 81-86. doi: 10.12259/j.issn.2095-610X.S20230302

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Jiawei DING, Jia WANG, Shu YANG, Sulian CHEN, Jing LI. Analysis of HPV Detection in 18 449 Hospital Patients in Kunming and HPV Vaccination Recommendations[J]. Journal of Kunming Medical University, 2023, 44(3): 81-86. doi: 10.12259/j.issn.2095-610X.S20230302

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Analysis of HPV Detection in 18 449 Hospital Patients in Kunming and HPV Vaccination Recommendations

doi: 10.12259/j.issn.2095-610X.S20230302

1.
Dept. of Clinical Laboratory
2.
Dept. of Prevention and Health Care，Kunming Yan’an Hospital，Kunming Yunan 650051，China

Received Date: 2022-10-26
Publish Date: 2023-03-25

Abstract

Abstract

Objective To analyze the detection and subtype distribution characteristics of human papillomavirus （HPV） in the genital tract of the first outpatient in the hospital, and to provide reference for the prevention and vaccination of HPV in the region. Methods A total of 18449 first-diagnosed female patients in Yan 'an Hospital of Kunming City from January 2018 to December 2020 were selected as the research objects. Clinical data were collected and a retrospective study was used to analyze the total HPV infection and compare the HPV detection rates in different age groups and years. To analyze the prevalence of high-risk HPV （HR-HPV） and low-risk HPV （IR-HPV）. Results Among 18449 patients, 2520 were HPV positive, and the total detection rate of HPV was 13.7%. HPV infection showed a downward trend from 2018 to 2020 （trend χ² = 4.95, P < 0.001）. According to age group, HPV detection showed a "V" type distribution, with the highest detection rate of 42.4% in the group less than 20 years old. The second group was ≥60 years old （19.7%）. The detection rate in 30-year old group was the lowest, only 12.0%, and the difference was statistically significant （ χ² = 7.080, P < 0.001）. The minimum age of infection was only 15 years and there were multiple infections. There were 973 cases of multiple infection, accounting for 5.3% of all patients and 38.6% of positive patients. Multiple infection was the main infection in < 20 years old group and ≥60 years old group, and single high-risk infection was the most common infection in 20-59 years old group. The top five detected HR-HPV types were HPV52, 53, 58, 16 and 51. The IR-HPV types were HPV81, 42, 43, 6 and 11. In HR-HPV, the dominant detected types changed from HPV52, 16 and 58 in 2018 to HPV52, 53 and 58 in 2019 and 2020. Conclusions HPV infection shows a trend of younger age, and the dominant types of HPV infection are different in different age groups. Attention should be paid to the prevention and treatment of HPV52, 53 and 58 infections in this region.
- HPV,
- Infection status,
- Vaccine,
- Vaccination recommendations

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