Research Progress of ACSM Protein Family in Tumor

Chenglu HE; Ya LI; Min ZHU; Min ZHONG; Yong DUAN

doi:10.12259/j.issn.2095-610X.S20230307

Volume 44 Issue 3

Mar. 2023

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Chenglu HE, Ya LI, Min ZHU, Min ZHONG, Yong DUAN. Research Progress of ACSM Protein Family in Tumor[J]. Journal of Kunming Medical University, 2023, 44(3): 149-154. doi: 10.12259/j.issn.2095-610X.S20230307

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Chenglu HE, Ya LI, Min ZHU, Min ZHONG, Yong DUAN. Research Progress of ACSM Protein Family in Tumor[J]. Journal of Kunming Medical University, 2023, 44(3): 149-154. doi: 10.12259/j.issn.2095-610X.S20230307

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Research Progress of ACSM Protein Family in Tumor

doi: 10.12259/j.issn.2095-610X.S20230307

Dept. of Clinical Laboratory，The 1st Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650032，China

Received Date: 2022-07-03
Available Online: 2023-03-02
Publish Date: 2023-03-25

Abstract

Abstract

Acyl-CoA Synthetase Medium Chains（ACSMs） are enzymes that can activate C6～C10 fatty acids and participate in the synthesis and decomposition of medium chain fatty acids. They are of great significance for cell survival. When tumor occurs, due to the rapid growth of tumor cells, more energy supply is required than that required by normal cells, except glycolysis, fatty acid energy supply is also an important way for tumor cells to obtain energy. The study of ACSMs, the key enzyme of medium chain fatty acid synthesis and metabolism, is of great significance to further explore the occurrence, development and prognosis of tumors. This review mainly introduces the research progress of ACSM family members and tumorigenesis and development in recent years.
- ACSMs,
- MCFAs,
- Cellular metabolism,
- Tumor

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References(47)

References

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