Research Progress on the Mechanisms of Autophagy in Hepatocellular Carcinoma

Yixuan CHEN; Lin WANG; Xiuhong XIA; Zaikun PENG; Yi DING; Runjiao SHI; Xuefen LEI

doi:10.12259/j.issn.2095-610X.S20230416

Volume 44 Issue 4

Apr. 2023

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Gao Cong , Liu Bing , Wang Kai . Study on the Relationship between Thyroid Function and Gastrointestinal Motility and Motilinlevels[J]. Journal of Kunming Medical University, 2018, 39(03): 115-118.

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Yixuan CHEN, Lin WANG, Xiuhong XIA, Zaikun PENG, Yi DING, Runjiao SHI, Xuefen LEI. Research Progress on the Mechanisms of Autophagy in Hepatocellular Carcinoma[J]. Journal of Kunming Medical University, 2023, 44(4): 159-164. doi: 10.12259/j.issn.2095-610X.S20230416

Gao Cong , Liu Bing , Wang Kai . Study on the Relationship between Thyroid Function and Gastrointestinal Motility and Motilinlevels[J]. Journal of Kunming Medical University, 2018, 39(03): 115-118.

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Research Progress on the Mechanisms of Autophagy in Hepatocellular Carcinoma

doi: 10.12259/j.issn.2095-610X.S20230416

1.
Dept. of Oncology
2.
Dept. of Hepatobiliary Surgery
3.
Dept. of Traditional Chinese Medicine， The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan 650101，China

Received Date: 2023-02-07
Available Online: 2023-04-12
Publish Date: 2023-04-25

Abstract

Abstract

Hepatocellular carcinoma（HCC）, characterized by high malignancy and rapid development, is one of the most common malignant tumors in the world. In most cases the tumor is inoperable when diagnois is made. Therefore, non-surgical treatment plays an increasingly important role. Although the curative effect of hepatocellular carcinoma has made great progress in recent years with the development of drugs and the innovation of radiotherapy technology, the prognosis of patients with hepatocellular carcinoma is still not ideal due to its high recurrence rate and frequent resistance to treatment. The development of hepatocellular carcinoma is the result of abnormal accumulation of multiple genes and cellular events. The autophagy dysregulation can cause the occurrence of hepatocellular carcinoma. Autophagy is closely related to the occurrence and development, metastasis and recurrence, and resistance to treatment of hepatocellular carcinoma. This paper aims to review the mechanisms of autophagy in hepatocellular carcinoma and provide reference for future anti-tumor studies on autophagy.
- Autophagy,
- Hepatocellular Carcinoma,
- Research progress

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References(48)

References

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