Analysis of Epidemiological Characteristics of Neonatal Rotavirus Infection from 2020 to 2022

Shuangshuang WANG; Liqin CHEN; Yaling LI; Weijie LI; Jiayi YANG

doi:10.12259/j.issn.2095-610X.S20230509

Volume 44 Issue 5

May 2023

Turn off MathJax

Article Contents

Abstract

References

Relative Articles

Article Navigation > Journal of Kunming Medical University > 2023 > 44(5): 26-31

Bo LI, Jian-lin JIAO, Chuan-yi ZHANG, Ya-qiong QIU, Hao GUO, Huai-chang SUN, Zhi-cheng YU. The Electroencephalogram and Analysis of MPTP-Induced Tree Shrew Model for Parkinson's Disease[J]. Journal of Kunming Medical University, 2021, 42(5): 29-34. doi: 10.12259/j.issn.2095-610X.S20210506

Citation:

Shuangshuang WANG, Liqin CHEN, Yaling LI, Weijie LI, Jiayi YANG. Analysis of Epidemiological Characteristics of Neonatal Rotavirus Infection from 2020 to 2022[J]. Journal of Kunming Medical University, 2023, 44(5): 26-31. doi: 10.12259/j.issn.2095-610X.S20230509

Citation:

PDF( 599 KB)

Analysis of Epidemiological Characteristics of Neonatal Rotavirus Infection from 2020 to 2022

doi: 10.12259/j.issn.2095-610X.S20230509

Dept. of Infection Management，Children’s Hospital of Kunming Medical University，Kunming Yunnan 650228，China

Received Date: 2023-01-16
Available Online: 2023-05-12
Publish Date: 2023-05-25

Abstract

Abstract

Objective To study the epidemiological characteristics of neonatal rotavirus （RV） infection, and to provide the guidance for the treatment and prevention of clinical diseases and the formulation of prevention and treatment strategies for RV infection in hospitals. Methods The clinical data of newborns admitted to a 3A children’s hospital in Yunnan Province were retrospectively collected from January 2020 to December 2022. The RV antigen in feces was detected by group A rotavirus detection reagent （colloidal gold method）, and the clinical and epidemiological data of neonatal RV infection were compared and analyzed by SPSS 26.0. Results There were 261 cases of RV infection in 16761 newborn patients, and the infection rate was 1.56%, of which the infection rates in 2020-2022 were 1.97% （124/6298）, 1.01% （57/5660） and 1.67% （80/4803） respectively. The RV infection rate of male children was 1.39%, while that of female children was 1.79%, and the difference between them was statistically significant （P < 0.05）. The infection rate of rotavirus in newborns aged ≤7 days was significantly lower than that in newborns aged 8～28 days, and the difference was statistically significant （P < 0.05）. From 2020 to 2022, the neonatal RV infection rates in spring, summer, autumn and winter were 2.64% （102/3866）, 1.58% （71/4502）, 0.63% （28/4450） and 1.52% （60/3943） respectively, and the difference was statistically significant （P < 0.05）.The top four states （cities） of neonatal RV infection rates in different origin areas were 7.14% （3/42） in Diqing, 2.82% （2/71） in Pu’er, 2.31% （8/346） in Honghe and 2.19% （3/137） in Wenshan. Community infection accounted for 62.07% （162/261） and hospital infection accounted for 37.93% （99/261）. There were 22.22% （58/261） children with asymptomatic infection, and 77.78% （203/261） children with RV infection-related clinical symptoms such as diarrhea, fever and vomiting. There are differences between the different nationalities （χ² = 7.945, P < 0.05） and different RV antigen test results （χ² = 5.007, P < 0.05） in the presence or absence of symptoms of RV infection in newborns. Conclusion RV infection rate of hospitalized newborns is generally low, especially in late newborns, and the infection rate is higher in areas with relatively backward economic level. It is suggested that more attention should be paid to RV infection in newborns, health education for caregivers should be strengthened and comprehensive prevention measures should be formulated to control the neonatal rotavirus infection from the source.
- Neonatal,
- Rotavirus,
- Infection,
- Epidemiology

FullText(HTML)

References(14)

References

[1]	Lee B. Update on rotavirus vaccine underperformance in low- to middle-income countries and next-generation vaccines[J]. Hum Vaccin Immunother,2021,17(6):1787-1802. doi: 10.1080/21645515.2020.1844525
[2]	陈坤,刘小利,王盈盈,等. 婴幼儿急性肠炎中轮状病毒检验及结果分析[J]. 国际儿科学杂志,2018,45(6):493-494,497.
[3]	曹亿会,杨景晖,姜黎黎,等. 2017-2019年我国西南地区病毒性腹泻病原检测分析[J]. 公共卫生与预防医学,2021,32(1):10-13.
[4]	Li J, Wang H, Li D, et al. Infection status and circulating strains of rotaviruses in Chinese children younger than 5-years old from 2011 to 2018: Systematic review and meta-analysis[J]. Hum Vaccin Immunother, 2021, 17（6）: 1811-1817.
[5]	甸子芩,樊茂,蒋红君,等. 2015-2017年云南省轮状病毒感染情况及基因分型分析[J]. 中国病原生物学杂志,2019,14(1):78-82,87.
[6]	袁娇,汪际英,朱冬庆. 2016-2018年新生儿重症监护室内轮状病毒感染流行病学特点分析[J]. 现代预防医学,2019,46(21):3902-3905.
[7]	许小艳,甸子芩,杨景晖,等. 11620例住院新生儿中轮状病毒感染及其特征分析[J]. 国际儿科学杂志,2021,48(7):503-506.
[8]	郑灵玲,李世贤,李倩倩,等. 乌鲁木齐2009-2010年新生儿轮状病毒感染及其影响因素分析[J]. 中华全科医学,2018,16(12):2045-2048,2071.
[9]	Ahmed A A,Abedalthagafi M. Cancer diagnostics: The journey from histomorphology to molecular profiling[J]. Oncotarget,2016,7(36):58696-58708. doi: 10.18632/oncotarget.11061
[10]	郑灵玲,李倩倩,杨学磊. 新生儿轮状病毒感染筛查及影响因素分析[J]. 中国病原生物学杂志,2015,10(2):109-112.
[11]	张谦慎. 初乳在超低出生体重儿中的应用[J]. 中华围产医学杂志,2013,16(7):394-396.
[12]	骆洪梅,冉陆,孟玲,等. 2005-2018年中国5岁以下轮状病毒腹泻报告病例流行特征分析[J]. 中华预防医学杂志,2020,54(2):181-186.
[13]	李锦,汪萍,何祥英,等. 新生儿轮状病毒感染流行病学特征分析[J]. 中国病原生物学杂志,2017,12(9):883-886.
[14]	邓晓辉,康亚辉,张丽秀,等. 2017-2019年新生儿轮状病毒感染流行病学特征分析[J]. 中国妇幼保健,2022,37(14):2621-2624.

Relative Articles(20)

Relative Articles

[1]	Ruoyu WANG, Wei CHEN, Xun XU, Wende CAO, Yulan MIAO. Epidemiological Investigation and Risk Factors Analysis of Systemic Inflammatory Response Syndrome in 329 Children with Burn. Journal of Kunming Medical University, 2024, 45(5): 123-129. doi: 10.12259/j.issn.2095-610X.S20240519
[2]	Xiaoli SHANG, Junxue NI, Yeying WANG, Jiao SHAN, Na BAI, Song WANG. Clinical Epidemiological Characteristics of Mycoplasma Pneumoniae and Its Correlation with Climatic Environment. Journal of Kunming Medical University, 2023, 44(6): 97-101. doi: 10.12259/j.issn.2095-610X.S20230618
[3]	Shulan SHI, Lijuan QIU, Liyue KUI, Min SU, Bailing ZHOU, Rongjie LI, Jianming SUN. Diagnostic Value of Interleukin-6，Interleukin-10，High-sensitivity C-reactive Protein and Procalcitonin in Children with Acute Lymphoblastic Leukemia Complicated by Infection. Journal of Kunming Medical University, 2023, 44(1): 104-108. doi: 10.12259/j.issn.2095-610X.S20230115
[4]	Weijie LI, Liqin CHEN, Yaling LI, Yonghui HAN, Xiaojuan LI, Ruogu WANG. Epidemiology of CRKP Infection Outbreak in a Neonatal Intensive Care Unit. Journal of Kunming Medical University, 2023, 44(12): 144-149. doi: 10.12259/j.issn.2095-610X.S20231223
[5]	Ruanxian DAI, Qiang MENG, Guobing CHEN, Bin HAN, Dexing YANG, Wangao GUAN. Epidemiological Characteristics Among Emergency Triage Patients in a Comprehensive Tertiary Hospital in Kunming in 2020. Journal of Kunming Medical University, 2022, 43(8): 81-86. doi: 10.12259/j.issn.2095-610X.S20220811
[6]	Jie ZHANG, Hui SUN, Lihua MU, Dexing YANG, Chuanyun QIAN. Epidemiological investigation and Analysis of Pre-hospital Emergency Patients in Kunming. Journal of Kunming Medical University, 2022, 43(3): 108-112. doi: 10.12259/j.issn.2095-610X.S20220325
[7]	Zhiying LU, Meifen WANG, Junchao PENG, Zengqing DU, Yunjiao LUO, Wei MA. Comparison of Serum PCT, IL-6, SAA Levels and Clinical Characteristics between Rotavirus and Norovirus Enteritis in Children. Journal of Kunming Medical University, 2022, 43(8): 138-144. doi: 10.12259/j.issn.2095-610X.S20220823
[8]	Lijuan YIN, Lingyun BAO, Jing YAO. Effect of Mechanical Vibration Assisted Expectoration in Neonatal Infectious Pneumonia. Journal of Kunming Medical University, 2022, 43(3): 166-170. doi: 10.12259/j.issn.2095-610X.S20220315
[9]	Yang Hui Bo , Yu Run Liu , Miao Qin , Liu De Liang . . Journal of Kunming Medical University, 2020, 41(07): 144-148.
[10]	Xiao Yan , Mi Hong Ying , Hu Jian Ying , Liu Yu . . Journal of Kunming Medical University, 2020, 41(01): 73-79.
[11]	Yin Li Juan , Bao Ling Yun , Li Ling , Yuan Yuan . . Journal of Kunming Medical University, 2020, 41(06): 178-180.
[12]	Li TAN, Ming LI, Yu-xing SUN, Zhen ZHANG, Zheng-yan GAN. Molecular Epidemiology of Human Rhinovirus in 2 260 Children with Acute Lower Respiratory Tract Infection. Journal of Kunming Medical University, 2020, 41(12): 119-122. doi: 10.12259/j.issn.2095-610X.S20201233
[13]	He Ying Chun , Li Mei Lan , Dong Yun Hua , Fan Hong Ping . . Journal of Kunming Medical University, 2019, 40(04): 11-15.
[14]	Wan Yan . The Efficacy and Safety of Fusidic Acid Cream Combined with Halometasone Cream in the Treatment of Psoriasis Vulgaris. Journal of Kunming Medical University,
[15]	Bai Zhi Yao . . Journal of Kunming Medical University,
[16]	Wu Xiao Guang . . Journal of Kunming Medical University,
[17]	Zhang Jian Lan . . Journal of Kunming Medical University,
[18]	Xiong Li . . Journal of Kunming Medical University,
[19]	Li Ke Rong . Clinical Treatment of 15 Patients with Gastroparesis after Major Abdominal Surgery. Journal of Kunming Medical University,
[20]	. . Journal of Kunming Medical University,