The Clinical Data Analysis of 2 499 Patients with Nasopharyngeal Carcinoma in Yunnan

Xiaoli WANG; Hongwei YANG; Ting DING; Ruiping WU; Kuixuan ZHU

doi:10.12259/j.issn.2095-610X.S20230523

Volume 44 Issue 5

May 2023

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Article Navigation > Journal of Kunming Medical University > 2023 > 44(5): 154-161

Xiaoli WANG, Hongwei YANG, Ting DING, Ruiping WU, Kuixuan ZHU. The Clinical Data Analysis of 2 499 Patients with Nasopharyngeal Carcinoma in Yunnan[J]. Journal of Kunming Medical University, 2023, 44(5): 154-161. doi: 10.12259/j.issn.2095-610X.S20230523

Citation:

Xiaoli WANG, Hongwei YANG, Ting DING, Ruiping WU, Kuixuan ZHU. The Clinical Data Analysis of 2 499 Patients with Nasopharyngeal Carcinoma in Yunnan[J]. Journal of Kunming Medical University, 2023, 44(5): 154-161. doi: 10.12259/j.issn.2095-610X.S20230523

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The Clinical Data Analysis of 2 499 Patients with Nasopharyngeal Carcinoma in Yunnan

doi: 10.12259/j.issn.2095-610X.S20230523

Dept. of Radiotherapy，Yunnan Cancer Hospital，Kunming Yunnan 650118，China

Received Date: 2022-11-29
Publish Date: 2023-05-25

Abstract

Abstract

Objective To analyze the clinical characteristics of nasopharyngeal carcinoma patients in Yunnan on the basis of the clinical data of hospitalized patients, and provide a basis for preventive measures. Methods The clinical data of 2 499 patients with nasopharyngeal carcinoma diagnosed by pathology in Yunnan Cancer Hospital from January 2013 to December 2021 were collected. The incidence trend, region, ethnic distribution, gender and age, family history, first diagnosis symptoms, pathological type, clinical stage, EB virus and EGFR expression were analyzed. Results Among the patients with the nasopharyngeal carcinoma in Yunnan, the ratio of male to female was 2.5∶1, the average age of onset was 49 years old, and the highest age of onset was 41-50 years old. The clinical manifestations were mainly nasal symptoms and neck symptoms. The pathological type was mainly non-keratinizing squamous cell carcinoma, the positive rate of EGFR immunohistochemistry was high （91.57%）, the positive rate of EB virus was nearly 60 %, and the clinical stage was mainly stage III （45.06%） and stage IV （27.45%）. Conclusion The incidence of nasopharyngeal carcinoma in Yunnan is related to EB virus. The positive rate of EGFR is high. It is among the middle-aged and elderly men that the incidence rate of the disease is highest, with the majority being locally advanced patients locally advanced patients and most of them have the cervical lymph node metastasis at the first visit.
- Yunnan province,
- Nasopharyngeal tumor,
- Tumor staging,
- Retrospective study,
- Symptoms

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