Investigation on Occupational Exposure and Protection of Cytotoxic Drugs among PIVAS Personnel in Yunnan Province

Hongyin ZHANG; Hongmei ZHU; Huiqin ZHANG; Hongwen YAO; Guirong ZHU; Lin LI

doi:10.12259/j.issn.2095-610X.S20230722

Volume 44 Issue 7

Jul. 2023

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Article Navigation > Journal of Kunming Medical University > 2023 > 44(7): 105-112

Hongyin ZHANG, Hongmei ZHU, Huiqin ZHANG, Hongwen YAO, Guirong ZHU, Lin LI. Investigation on Occupational Exposure and Protection of Cytotoxic Drugs among PIVAS Personnel in Yunnan Province[J]. Journal of Kunming Medical University, 2023, 44(7): 105-112. doi: 10.12259/j.issn.2095-610X.S20230722

Citation:

Hongyin ZHANG, Hongmei ZHU, Huiqin ZHANG, Hongwen YAO, Guirong ZHU, Lin LI. Investigation on Occupational Exposure and Protection of Cytotoxic Drugs among PIVAS Personnel in Yunnan Province[J]. Journal of Kunming Medical University, 2023, 44(7): 105-112. doi: 10.12259/j.issn.2095-610X.S20230722

Citation:

Hongyin ZHANG, Hongmei ZHU, Huiqin ZHANG, Hongwen YAO, Guirong ZHU, Lin LI. Investigation on Occupational Exposure and Protection of Cytotoxic Drugs among PIVAS Personnel in Yunnan Province[J]. Journal of Kunming Medical University, 2023, 44(7): 105-112. doi: 10.12259/j.issn.2095-610X.S20230722

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Investigation on Occupational Exposure and Protection of Cytotoxic Drugs among PIVAS Personnel in Yunnan Province

doi: 10.12259/j.issn.2095-610X.S20230722

1.
Dept. of Pharmacy，Yunnan Cancer Hospital，The 3rd Affiliated Hospital of Kunming Medical University，Kunming Yunnan，650118
2.
Dept. of Pharmacy，The 2nd Affiliated Hospital of Yunnan University of Chinese Medicine，Kunming Yunnan 650041
3.
Key Laboratory of Natural Drug Pharmacology，Kunming Medical University，Kunming Yunnan 650500，China

Received Date: 2023-05-08
Available Online: 2023-07-17
Publish Date: 2023-07-25

Abstract

Abstract

Objective To understand the occupational exposure situation of staff in the pharmacy intravenous admixture services （PIVAS） of Yunnan Province and identify the issues related to occupational protection in PIVAS staff. Methods Based on the “Quality Management Specification for Intravenous Dispensing of Cytotoxic Drugs in Medical Institutions” issued by the Chinese Pharmaceutical Association, a questionnaire survey was designed and tested using the Delphi method and reliability and validity analysis. The survey was conducted through “Wenjuanxing” in December 2021 among PIVAS staff in Yunnan Province hospitals. Results A total of 393 questionnaires were distributed and collected. After excluding invalid questionnaires based on inclusion and exclusion criteria, 382 valid questionnaires were obtained, with an effective response rate of 97.2%. The survey results showed that PIVAS staff in tertiary hospitals had more exposure to cytotoxic drugs and higher occupational exposure risks compared to staff in secondary hospitals. The hazards of cytotoxic drugs significantly increased with exposure time. There were issues with inadequate awareness of cytotoxic drug protection, improper handling of accidental exposure, and incomplete protection systems. Conclusions Occupational exposure is an important threat to the health of healthcare workers. It is necessary to establish and improve occupational protection management systems, enhance the awareness of occupational protection among healthcare workers, and implement effective occupational protection measures in order to reduce the hazards of occupational exposure.
- PIVAS,
- Chemotherapy drugs,
- Occupational exposure,
- Occupational protection

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References(20)

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