Value of Inferior Vena Cava Respiratory Variation in Assessing Volume Responsiveness in Patients with Septic Shock

Xiaoxue LIU; Meiju LI; Jing XIA

doi:10.12259/j.issn.2095-610X.S20230816

Volume 44 Issue 8

Aug. 2023

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Xiaoxue LIU, Meiju LI, Jing XIA. Value of Inferior Vena Cava Respiratory Variation in Assessing Volume Responsiveness in Patients with Septic Shock[J]. Journal of Kunming Medical University, 2023, 44(8): 95-99. doi: 10.12259/j.issn.2095-610X.S20230816

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Xiaoxue LIU, Meiju LI, Jing XIA. Value of Inferior Vena Cava Respiratory Variation in Assessing Volume Responsiveness in Patients with Septic Shock[J]. Journal of Kunming Medical University, 2023, 44(8): 95-99. doi: 10.12259/j.issn.2095-610X.S20230816

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Value of Inferior Vena Cava Respiratory Variation in Assessing Volume Responsiveness in Patients with Septic Shock

doi: 10.12259/j.issn.2095-610X.S20230816

Dept. of Emergency Medicine，The 1st Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650032，China

Received Date: 2023-05-13
Available Online: 2023-09-12
Publish Date: 2023-08-30

Abstract

Abstract

Objective To explore inferior vena cava respiratory variation assessing volume responsiveness in patients with septic shock. Methods A total of 60 patients with septic shock in the Emergency Department of the First Affiliated hospital of a medical university from August 2018 to May 2019 were selected. According to the different guidance methods of fluid resuscitation, they were divided into the Variance of Inferior Vena Cava （VIVC） guided fluid resuscitation group A and Central Venous Pressure （CVP） guided fluid resuscitation in group B. Stroke volume （SV） was evaluated by ultrasound before and 30min, 1h, 3h and 6h after fluid infusion. Lactate （Lac）, brain natriuretic peptide （BNP）, base excess （BE） and heart rate （HR） , respiratory rate （RR）, central venous oxygen saturation （SCVO2）, mean arterial pressure （ MAP） and urine volume were recorded at the above time points in both groups and were compared. Results MAP, SCVO2, and urine volume increased, while RR decreased in the same group at different time points with the progress of fluid infusion （P < 0.05）. However, there was no significant difference in MAP, RR, SCVO2 and urine volume between the two groups （P > 0.05）. After stopping resuscitation, BNP increased and HR decreased in the two groups, and BNP and HR in group B were higher than those in group A （P < 0.05）. Lac decreased and BE increased in the two groups, but there was no significant difference between the two groups （P > 0.05）. Conclusion Compared with CVP, IVC variability is equally valuable in evaluating fluid responsiveness in patients with septic shock, and it is safer because it causes less BNP elevation and avoids fluid overload.
- Variance of inferior vena cava,
- Central venous pressure,
- Septic shock,
- Fluid resuscitation

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References(16)

References

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