Volume 44 Issue 9
Sep.  2023
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Jiamei SONG, Yushi MENG, Jingsi CHEN, Lin CHEN, Wen FAN, Jin YAN, Yang LIU. Effects of Different FET Schemes on Endometrial Thickness,Endometrial Blood Flow and Pregnancy Outcome in Patients with Endometrial Tuberculosis[J]. Journal of Kunming Medical University, 2023, 44(9): 93-99. doi: 10.12259/j.issn.2095-610X.S20230911
Citation: Jiamei SONG, Yushi MENG, Jingsi CHEN, Lin CHEN, Wen FAN, Jin YAN, Yang LIU. Effects of Different FET Schemes on Endometrial Thickness,Endometrial Blood Flow and Pregnancy Outcome in Patients with Endometrial Tuberculosis[J]. Journal of Kunming Medical University, 2023, 44(9): 93-99. doi: 10.12259/j.issn.2095-610X.S20230911

Effects of Different FET Schemes on Endometrial Thickness,Endometrial Blood Flow and Pregnancy Outcome in Patients with Endometrial Tuberculosis

doi: 10.12259/j.issn.2095-610X.S20230911
  • Received Date: 2023-04-06
    Available Online: 2023-09-21
  • Publish Date: 2023-09-30
  •   Objective  To compare and analyze the effects of three different frozen-thawed embryo transfer(FET) protocols natural cycle(NC), hormone replacement cycle(HRT) and gonadotropin releasing hormone agonist-hormone replacement cycle(GnRH-a-HRT) on endometrial thickness on the day of endometrial transformation, endometrial blood flow and the pregnancy outcome of FET in patients with endometrial tuberculosis.   Methods  Patients with endometrial tuberculosis who underwent FET in the Reproductive Medicine Department of the Second Affiliated Hospital of Kunming Medical University from January 1st, 2017 to January 1st, 2021 were collected. According to the FET endometrial preparation protocol, the patients were divided into NC group, HRT group and GnRH-a-HRT group respectively. After the comparation and analysis to the endometrial thickness, endometrial blood flow and embryo transfer outcomes were compared among the three groups;   Results  The embryo implantation rate, clinical pregnancy rate, continuing pregnancy rate and live birth rate in GnRH-a HRT group were higher than those in HRT group(P < 0.05). The embryo implantation rate, clinical pregnancy rate, ongoing pregnancy rate and live birth rate in HRT group were higher than those in NC group, and the differences were statistically(P < 0.05). The endometrial thickness and endometrial blood flow of the three groups, it was found that the endometrial thickness and PSV value of the endometrial blood flow in the GnRH-a HRT group were higher than those in the HRT group and NC group, while the RI value and PI value of the endometrial blood flow were lower than those in the HRT group and NC group(P < 0.05). The endometrial thickness and PSV of the HRT group were higher than those of the NC group, while the RI and PI of the endometrial blood flow were lower than those of the NC group, and the differences were statistically(P < 0.05);   Conclusion  GnRH-a-HRT can improve the endometrial thickness and PSV value of endometrial blood flow on the day of endometrial transformation, reduce the RI and PI value of endometrial blood flow, and finally improve the pregnancy outcome of FET for patients with endometrial tuberculosis.
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