Volume 44 Issue 11
Nov.  2023
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Wenyou XIE, Tongheng HUANG, Yanru YANG, Jinyang LIU. Clinical Study of Neuronavigation-assisted Endoscopic Transnasal Sphenoid Approach for Resection of Pituitary Tumors[J]. Journal of Kunming Medical University, 2023, 44(11): 108-112. doi: 10.12259/j.issn.2095-610X.S20231116
Citation: Wenyou XIE, Tongheng HUANG, Yanru YANG, Jinyang LIU. Clinical Study of Neuronavigation-assisted Endoscopic Transnasal Sphenoid Approach for Resection of Pituitary Tumors[J]. Journal of Kunming Medical University, 2023, 44(11): 108-112. doi: 10.12259/j.issn.2095-610X.S20231116

Clinical Study of Neuronavigation-assisted Endoscopic Transnasal Sphenoid Approach for Resection of Pituitary Tumors

doi: 10.12259/j.issn.2095-610X.S20231116
  • Received Date: 2023-07-19
    Available Online: 2023-11-13
  • Publish Date: 2023-11-30
  •   Objective  To explore and analyze the clinical application efficacy and prospect of neuronavigation positioning assisted endoscopic transnasal sphenoid approach for resection of pituitary adenomas under general anesthesia.   Methods  A total of 68 patients who underwent pituitary adenoma surgery at the Neurosurgery Department of Yangjiang People's Hospital from September 2018 to April 2023 were collected and divided into two groups: an experimental group of 34 patients(neuronavigation-assisted endoscopic transsphenoidal approach for pituitary adenoma resection) and a control group of 34 patients(microscopic transsphenoidal approach for pituitary adenoma resection). The surgery-related indicators, complication indicators, and preoperative and postoperative endocrine hormone indicators were analyzed and evaluated in both groups.   Results  The probability of total tumor resection in the experimental group was significantly higher than that in the control group in postoperative imaging comparison, with statistical significance(P<0.05). The comparison of surgical time, bleeding volume, hospitalization time, surgical bleeding volume, and postoperative patient hormone indicators showed that the experimental group was significantly lower than the control group, and the difference was statistically significant(P<0.05).   Conclusions  Neuronavigation positioning assisted endoscopic transnasal sphenoid approach for resection of pituitary adenoma has the advantages of small trauma, safety, high efficiency, short hospital stay, and high total resection rate. This represents a novel and effective strategy for wide clinical application.
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