Investigation and Analysis of Vitamin K Level Distribution in 1177 Infants of Different Age Groups

Jinyan ZHOU; Kerong LI; Yan MA; Jiqiang WANG; Zhengming ZHANG; Wang LI

doi:10.12259/j.issn.2095-610X.S20240114

Volume 45 Issue 1

Jan. 2024

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Jinyan ZHOU, Kerong LI, Yan MA, Jiqiang WANG, Zhengming ZHANG, Wang LI. Investigation and Analysis of Vitamin K Level Distribution in 1177 Infants of Different Age Groups[J]. Journal of Kunming Medical University, 2024, 45(1): 83-86. doi: 10.12259/j.issn.2095-610X.S20240114

Citation:

Jinyan ZHOU, Kerong LI, Yan MA, Jiqiang WANG, Zhengming ZHANG, Wang LI. Investigation and Analysis of Vitamin K Level Distribution in 1177 Infants of Different Age Groups[J]. Journal of Kunming Medical University, 2024, 45(1): 83-86. doi: 10.12259/j.issn.2095-610X.S20240114

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Investigation and Analysis of Vitamin K Level Distribution in 1177 Infants of Different Age Groups

doi: 10.12259/j.issn.2095-610X.S20240114

1.
Dept. of Pediatrics ，Yan’An Hospital Affiliated to Kunming Medical Univerasity，Kunming Yunnan，650051
2.
Dept.of Pediatrics，The 1st People’s Hospital of Xundian Hui and Yi Autonomous，Xundian Yunnan 655200
3.
Dept. of Pediatrics，The 3rd People’s Hospital of Yunnan Province，Kunming Yunnan 650011
4.
Dept. of Pediatrics，Guandu District People’s Hospital of Kunming City，Kunming Yunnan 650220，China

Received Date: 2023-09-16
Available Online: 2024-01-06
Publish Date: 2024-01-25

Abstract

Abstract

Objective T o investigate the distributions of vitamin K1 and K2 in infants of different age groups by comparing the serum levels of vitamin K1 and K2 in them. Methods 1177 infants from 0 to 3 months were divided into 6 age groups. Those born/treated in the subject units（pediatrics, neonatology, child health care, obstetrics） were selected as the study subjects and grouped by age: 0～3 days（591 cases）, 4～7 days（255 cases）, 8～5 days（104 cases）, 1 month（118 cases）, 2 months（40 cases）, and 3 months（69 cases）. General data of the infants were collected, and the serum vitamin K1 and K2 levels were determined by HPLC-mass spectrometry（LC-MS） on a unified platform, and analyzed from the distribution of vitamin K1 and K2 at different ages. Results The distributions of vitamin K1 and K2 levels were statistically significant（P <0.001）; newborns were highly vulnerable to vitamin K1 deficiency, and vitamin K2 deficiency was higher than vitamin K1 with age. Conclusion Maintaining the normal growth of vitamin K1 and K2 is crucial for the normal growth and development of infants of all ages, so we should pay close attention to the monitoring and supplement of vitamin K1 and K2.
- Vitamin K1,
- Vitamin K2,
- Horizontal distribution

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References(22)

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