Volume 45 Issue 1
Jan.  2024
Turn off MathJax
Article Contents
Sixiang LIU, Yongkun HUANG, Shulan SHI, Jingjing SUN, Lisi LUO, Li WANG, Yu LING. Analysis of Vitamin D in Children with Henoch-Schonlein Purpura[J]. Journal of Kunming Medical University, 2024, 45(1): 133-135. doi: 10.12259/j.issn.2095-610X.S20240122
Citation: Sixiang LIU, Yongkun HUANG, Shulan SHI, Jingjing SUN, Lisi LUO, Li WANG, Yu LING. Analysis of Vitamin D in Children with Henoch-Schonlein Purpura[J]. Journal of Kunming Medical University, 2024, 45(1): 133-135. doi: 10.12259/j.issn.2095-610X.S20240122

Analysis of Vitamin D in Children with Henoch-Schonlein Purpura

doi: 10.12259/j.issn.2095-610X.S20240122
  • Received Date: 2023-10-27
    Available Online: 2024-01-06
  • Publish Date: 2024-01-25
  •   Objective  To analyze the changes of vitamin D in children with Henoch-Schonlein purpura(HSP).  Methods  130 children with HSP from Kunming Children’ s Hospital between July 2022-July 2023 were selected as the study subjects and 100 healthy children were selected during the same period as the control group. The blood samples were collected from the children with HSP and the healthy children. The content of vitamin D was measured by Kunming Kingmed Institute for Clinical Laboratory.   Results  The content of 25(OH) D in children with HSP was lower than that in healthy children, and the difference was statistically significant(P < 0.01).The proportion of vitamin D insufficiency in children with HSP was higher than that in healthy children, and the difference was statistically significant(P < 0.01).  Conclusion  The children with HSP are prone to vitamin D insufficiency. Vitamin D supplementation may provide a new method for the treatment of HSP.
  • loading
  • [1]
    王晓川. 儿童临床免疫功能评价[J]. 实用儿科临床杂志,2008,23(21):1635-1638.
    [2]
    罗雄燕,吴凤霞,赵岩,等. 维生素D与自身免疫性疾病[J]. 中华临床免疫和变态反应杂志,2010,4(4):312-316.
    [3]
    Dimeloe S,Rice L V,Chen H,et al. Vitamin D (1,25 ( oh)2d3) induces alpha-1-antitrypsin synthesis by cd4(+) t cells,which is required for 1,25(oh)2d3-driven il-10[J]. J Steroid Biochem Mol Biol,2019,30(189):1-9.
    [4]
    中华医学会儿科学分会免疫学组,《中华儿科杂志》编辑委员会. 儿童过敏性紫癜循证诊治建议[J]. 中华儿科杂志,2013,51(7):502-507.
    [5]
    中华医学会儿科学分会儿童保健学组,《中华儿科杂志》编辑委员会. 儿童微量营养素缺乏防治建议[J]. 中华儿科杂志,2010,48(7):502-509.
    [6]
    段俊彦,葛许华. 维生素D在自身免疫性疾病及儿科应用中的研究进展[J]. 中国合理用药探索,2022,19(4):1-6.
    [7]
    Herrmann M,Farrell C L,Pusceddu I,et al. Assessment of vitamin D status -a changing landscape[J]. Clinical Chemistry and Laboratory Medicine,2016,55(1):3-26.
    [8]
    张爱飞,冯正平. 维生素D免疫调节的研究进展[J]. 中国骨质疏松杂志,2019,25(4):564-569.
    [9]
    李水军. 维生素D代谢及25-羟基维生素D测定方法研究进展[J]. 国际检验医学杂志,2012,33(24):3028-3030.
    [10]
    Vanherwegen A S,Gysemans C,Mathieu C. Vitamin D endocrinology on the cross-road between immunity and metabolism[J]. Molecular and Cellular Endocrinology,2017,1(453):52-67.
    [11]
    Rao Z,Zhang N,Xu N,et al. 1,25-Dihydroxyvitamin D inhibits LPS-induced high-mobility group box 1 (HMGB1) secretion via targeting the NF-E2-related factor 2-Hemeoxygenase-1- HMGB 1 pathway in macrophages[J]. Frontiers in Immunolog,2017,8(9):357.
    [12]
    赖兰敏,彭桉平,陈曲波. 1,25二羟维生素D3的免疫调节及其在自身免疫性疾病中的研究进展[J]. 中国免疫学杂志,2019,35(17):2169-2173. doi: 10.3969/j.issn.1000-484X.2019.17.024
    [13]
    王颖,苏娟. 维生素D在自身免疫性疾病中的研究进[J]. 风湿病与关节炎,2017,6(2):76-80.
  • Relative Articles

    [1] Nan ZHANG, Yanling YANG, Qingqing WAN, Jiang ZHAO, Min PENG, Xiao ZHU, Zhitao LIU, Qiang ZHANG. Analysis on Nutritional Status of Vitamin D Among Adults of 6 Ethnic Minority Groups Native to Yunnan Province. Journal of Kunming Medical University, 2024, 45(2): 105-111.  doi: 10.12259/j.issn.2095-610X.S20240214
    [2] Yuyu ZHANG, You LU, Yu LIU. Relationship between Levels of Serum 25-hydroxyvitamin D,Calcium,Zinc and Growth and Development of Children. Journal of Kunming Medical University, 2024, 45(7): 126-131.  doi: 10.12259/j.issn.2095-610X.S20240719
    [3] Shujin LI, Yanfei YANG, Min SU, Yu LING, Yanqiong RAO, Jihua CUI. Single Nucleotide Polymorphisms in Children with Attention Deficit Hyperactivity Disorder Comorbid Emotion Problems. Journal of Kunming Medical University, 2023, 44(4): 139-147.  doi: 10.12259/j.issn.2095-610X.S20230420
    [4] Lu LI, Yunfen TIAN. Research Progress on Intestinal Microflora and Non-alcoholic Fatty Liver Disease in Children. Journal of Kunming Medical University, 2023, 44(7): 148-155.  doi: 10.12259/j.issn.2095-610X.S20230708
    [5] Yongyi ZOU, Zhiye QI, Dongmei SUN, Chunmei Wan, Kun LIANG. Effects of Different Vitamin D Doses on Bone Metabolism and Growth and Development Indicators of Preterm infants:A Cohort Study. Journal of Kunming Medical University, 2023, 44(11): 76-81.  doi: 10.12259/j.issn.2095-610X.S20231111
    [6] Tong XU, Yantuanjin MA, Yuhang ZHANG, Qiuyue HE, Wei HUANG, Mengxin LU, Jian TANG, Jianping HE, Guoqing JIANG, Yuan QIAN. Second-generation Sequencing Study of Trophoblast Cells in vitro Stimulated by Different Concentrations of Vitamin D. Journal of Kunming Medical University, 2022, 43(10): 1-9.  doi: 10.12259/j.issn.2095-610X.S20221021
    [7] Ying ZHANG, Hong GAO, Cuixiang ZHANG, Zeying CHEN, Hongqun ZOU, Liqiong LI, Jupin YANG, Yuexin HU. Helicobacter Pylori Infection in Children and its Correlation with Iron Deficiency Anemia. Journal of Kunming Medical University, 2022, 43(4): 103-106.  doi: 10.12259/j.issn.2095-610X.S20220418
    [8] Xinyi LI, Yong YUAN, Yan FU, Yan ZHU. Distribution of Vitamin D Levels in Women of Different Ages in Early Pregnancy. Journal of Kunming Medical University, 2022, 43(4): 137-141.  doi: 10.12259/j.issn.2095-610X.S20220421
    [9] Chen WANG, Sha LI, Boxue ZHANG, Jinhua HE. Effect of VitD Supplementation on the Improvement of Autoimmune Thyroiditis in Childbearing Age Females. Journal of Kunming Medical University, 2022, 43(9): 135-140.  doi: 10.12259/j.issn.2095-610X.S20220907
    [10] Yong YUAN, Xinyi LI, Yan FU, Yan ZHU. Analysis of Vitamin D Level in Pregnant Women and Infants in Kunming and Study on the Relationship between Fasting Blood Glucose Level and Vitamin D Level during Pregnancy. Journal of Kunming Medical University, 2022, 43(9): 125-129.  doi: 10.12259/j.issn.2095-610X.S20220931
    [11] Shu-lan SHI, Xi-ting DAI, Guang-zhou ZHAO, Xiao Juan LI, Rong-jie LI, Ming-biao MA. Application of 16SrRNA Gene Detection in the Early Diagnosis of Bacterial Meningitis in Children. Journal of Kunming Medical University, 2021, 42(5): 120-125.  doi: 10.12259/j.issn.2095-610X.S20210522
    [12] Hai-lin HUANG, Xiao-juan LI, Jian-wen YIN, Hong-chao JIANG. Distribution and Drug Sensitivity of Salmonella and Shigella in Children with Infectious Diarrhea in Kunming from 2017 to 2020. Journal of Kunming Medical University, 2021, 42(7): 83-87.  doi: 10.12259/j.issn.2095-610X.S20210713
    [13] Ling-ling YAN, Zhi-hong QIAN, Yue NI, Huang WU. Clinical Investigation of Vitamin D and Calcium Supplement’ Effect on the Occurrence of Cardiovascular and Cerebrovascular Diseases in POP Patients. Journal of Kunming Medical University, 2021, 42(10): 139-144.  doi: 10.12259/j.issn.2095-610X.S20211036
    [14] Yan GAO, Xiang-lei TONG, Hao-ran TANG, Li WU. Analysis of Serum Fat-soluble Vitamin Levels in Infants and Children in Anning City. Journal of Kunming Medical University, 2021, 42(4): 44-48.  doi: 10.12259/j.issn.2095-610X.S20210408
    [15] Zhang Li Li , Zhao Lin , Li Yan Hong , Wu Jie , Zheng Wen Jing , Shang Xiao Li . . Journal of Kunming Medical University, 2020, 41(08): 126-133.
    [16] Liu Xing , Sun Hui , Du Ying Rong , Chen Jie , Ou Yang Bing , Zhang Le . . Journal of Kunming Medical University, 2020, 41(03): 22-29.
    [17] Li Yan Hong , Zhang Xian , Zhang Jun Tao , Zhao Meng Ru , Tang Jia Hui , Li Lin Xia . . Journal of Kunming Medical University, 2018, 39(11): 67-73.
    [18] Wen Jie , Du San Jun , Wang Xiao Mei , Wu Yuan Hui , An Guo Zhi , Huo Yan . . Journal of Kunming Medical University, 2017, 38(03): 90-93.
    [19] Ji Xiao Fei , Zhang Ting Ting , Zhao Bo , Liu Mei , Xiong Jing Jing , Liao Ya Bin , Zhao Ya Ling , Ding Zhen Bo , Huang Yong Kun . Change and Significance of Cytokine Levels in Children with Different Types of Henoch-Schonlein Purpura. Journal of Kunming Medical University, 2016, 37(11): 46-50.
    [20] . Clinical Electroencephalogram Research of Children Henoch-Schonlein Purpura with Headache. Journal of Kunming Medical University,
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(2)

    Article Metrics

    Article views (1024) PDF downloads(13) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return