The Distribution and Drug Resistance of Pathogenic Bacteria in Respiratory Tract Infections in Children from 2019 to 2022

Xuelin ZHANG; Lu LIU; Yanzhi CHEN; Caijun ZHA; Yanli LI

doi:10.12259/j.issn.2095-610X.S20240125

Volume 45 Issue 1

Jan. 2024

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Article Navigation > Journal of Kunming Medical University > 2024 > 45(1): 149-155

Xuelin ZHANG, Lu LIU, Yanzhi CHEN, Caijun ZHA, Yanli LI. The Distribution and Drug Resistance of Pathogenic Bacteria in Respiratory Tract Infections in Children from 2019 to 2022[J]. Journal of Kunming Medical University, 2024, 45(1): 149-155. doi: 10.12259/j.issn.2095-610X.S20240125

Citation:

Xuelin ZHANG, Lu LIU, Yanzhi CHEN, Caijun ZHA, Yanli LI. The Distribution and Drug Resistance of Pathogenic Bacteria in Respiratory Tract Infections in Children from 2019 to 2022[J]. Journal of Kunming Medical University, 2024, 45(1): 149-155. doi: 10.12259/j.issn.2095-610X.S20240125

Citation:

Xuelin ZHANG, Lu LIU, Yanzhi CHEN, Caijun ZHA, Yanli LI. The Distribution and Drug Resistance of Pathogenic Bacteria in Respiratory Tract Infections in Children from 2019 to 2022[J]. Journal of Kunming Medical University, 2024, 45(1): 149-155. doi: 10.12259/j.issn.2095-610X.S20240125

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The Distribution and Drug Resistance of Pathogenic Bacteria in Respiratory Tract Infections in Children from 2019 to 2022

doi: 10.12259/j.issn.2095-610X.S20240125

Xuelin ZHANG¹,
Lu LIU¹,
Yanzhi CHEN¹,
Caijun ZHA^{1, 2},
Yanli LI^{3
,
,}

1.
The Laboratory
2.
The Research Center of Baoshan People’ Hospital，Baoshan Yunnan 678000
3.
The 1st Ward Dept. of Respiratory and Critical Care Medicine，Yan’an Hospital of Kunming/Yan’an Hospital Affiliated to Kunming Medical University，Kunming Yunnan 650051，China

Received Date: 2023-10-12
Available Online: 2024-01-03
Publish Date: 2024-01-25

Abstract

Abstract

Objective To analyze the clinical characteristics and the antimicrobial resistance of respiratory tract infection in children in Baoshan City, guide clinicians to rationally apply antibiotics, and improve the success rate of treatment. Methods Retrospective analysis of the distribution characteristics and drug sensitivity results of 1039 strains of pathogens detected in pediatric inpatients of hospitals from 2019 to 2022 was conducted. Results The main pathogens causing the respiratory infections in children in Baoshan area were Streptococcus pneumoniae, Escherichia coli, Staphylococcus aureus, Haemophilus influenzae, Klebsiella pneumoniae and Pseudomonas aeruginosa.Analysis of the drug sensitivity results of pathogenic bacteria with a detected quantity greater than 80 revealed that Streptococcus pneumoniae had a high resistance rate to erythromycin, clindamycin, and compound sulfamethoxazole. The resistance rates of penicillin, ceftriaxone, cefotaxime, and meropenem were P<0.05, and the difference was statistically significan. Methicillin-resistant Staphylococcus aureus（MRSA） was11.1%; CTX/CRO-R-ECO, CTX/CRO-R-KPN, CR-ECO and CR-KPN were lower than the 2021 ISPED level; The P.aeruginosa drug resistance rate and H.influenzae’ s ampicillin and ampicillin/sulbactam were higher than the 2021 ISPED level. Conclusion The treatment of respiratory tract infections in pediatric patients faces great challenges.The non-standard use of empirical medication has led to the emergence of multidrug-resistant bacteria, and the selection of anti infection treatment drugs is limited. Therefore, it is imperative to grasp the epidemic characteristics and drug resistance of pathogenic bacteria in the local area.
- Respiratory infection,
- Antimicrobial,
- Pathogenic bacteria,
- Antimicrobial resistance

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References(14)

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