Value of Head and Neck 4D-CTA Combined with SDF-1a/CXCR4 Signaling Pathway in Assessing the Risk of Ruptured Intracranial Posterior Communicating Aneurysms

Yiming XU; Jianfeng ZHONG; Bin LI; Xinyan ZHOU; Hongli ZHU; Jing LIANG; Chengde LIAO

doi:10.12259/j.issn.2095-610X.S20240309

Volume 45 Issue 3

Mar. 2024

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Article Navigation > Journal of Kunming Medical University > 2024 > 45(3): 59-64

Yiming XU, Jianfeng ZHONG, Bin LI, Xinyan ZHOU, Hongli ZHU, Jing LIANG, Chengde LIAO. Value of Head and Neck 4D-CTA Combined with SDF-1a/CXCR4 Signaling Pathway in Assessing the Risk of Ruptured Intracranial Posterior Communicating Aneurysms[J]. Journal of Kunming Medical University, 2024, 45(3): 59-64. doi: 10.12259/j.issn.2095-610X.S20240309

Citation:

Yiming XU, Jianfeng ZHONG, Bin LI, Xinyan ZHOU, Hongli ZHU, Jing LIANG, Chengde LIAO. Value of Head and Neck 4D-CTA Combined with SDF-1a/CXCR4 Signaling Pathway in Assessing the Risk of Ruptured Intracranial Posterior Communicating Aneurysms[J]. Journal of Kunming Medical University, 2024, 45(3): 59-64. doi: 10.12259/j.issn.2095-610X.S20240309

Citation:

Yiming XU, Jianfeng ZHONG, Bin LI, Xinyan ZHOU, Hongli ZHU, Jing LIANG, Chengde LIAO. Value of Head and Neck 4D-CTA Combined with SDF-1a/CXCR4 Signaling Pathway in Assessing the Risk of Ruptured Intracranial Posterior Communicating Aneurysms[J]. Journal of Kunming Medical University, 2024, 45(3): 59-64. doi: 10.12259/j.issn.2095-610X.S20240309

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Value of Head and Neck 4D-CTA Combined with SDF-1a/CXCR4 Signaling Pathway in Assessing the Risk of Ruptured Intracranial Posterior Communicating Aneurysms

doi: 10.12259/j.issn.2095-610X.S20240309

1.
Dept. of Radiology，Yan’an Hospital，Kunming Yunnan 650051，China

Received Date: 2023-12-15
Available Online: 2024-03-12
Publish Date: 2024-03-30

Abstract

Abstract

Objective To investigate the value of 4D-CTA combined with SDF-1a/CXCR4 signaling pathway in evaluating the risk of intracranial aneurysm rupture. Methods Fifty patients with unruptured intracranial posterior communicating aneurysms and 50 patients with ruptured intracranial posterior communicating aneurysms were divided into unruptured group 1 and ruptured group 1. All patients underwent 4D-CTA examination and serumSDF-1alevel was detected. Non-ruptured group 1 was followed up for 12 months（After conservative treatment）, on this basis, patients with ruptured posterior communicating aneurysms were included in ruptured group 2, and patients with unruptured posterior communicating aneurysms were included in non-ruptured group 2. Results The AUC values of Wn, AR, L, SR, SDF-1a and their combinations in diagnosing ruptured intracranial posterior communicating aneurysms were all greater than 0.70.The AUC values of Wn, AR, L, SR, SDF-1a and their combinations in predicting ruptured intracranial posterior communicating aneurysms in ruptured group 2 were all greater than 0.70. Conclusion 4D-CTA combined with SDF-1acan effectively distinguish ruptured intracranial posterior communicating aneurysms and predict the risk of rupture.
- 4D-CTA,
- SDF-1a,
- Ruptured posterior intracranial communicating aneurysm

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References(15)

References

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