Volume 45 Issue 4
Apr.  2024
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Haiping HE. Analysis of Coagulation Function Indexes in Elderly Patients with Novel Coronavirus Pneumonia[J]. Journal of Kunming Medical University, 2024, 45(4): 99-104. doi: 10.12259/j.issn.2095-610X.S20240414
Citation: Haiping HE. Analysis of Coagulation Function Indexes in Elderly Patients with Novel Coronavirus Pneumonia[J]. Journal of Kunming Medical University, 2024, 45(4): 99-104. doi: 10.12259/j.issn.2095-610X.S20240414

Analysis of Coagulation Function Indexes in Elderly Patients with Novel Coronavirus Pneumonia

doi: 10.12259/j.issn.2095-610X.S20240414
  • Received Date: 2023-05-19
    Available Online: 2024-04-07
  • Publish Date: 2024-04-29
  •   Objective  To explore the clinical significance of coagulation function indexes in the diagnosis and treatment of elderly patients with novel coronavirus pneumonia.   Methods  This study retrospectively analyzed 68 elderly patients with novel coronavirus infection admitted to The Wuhu Hospital, East China Normal University from December 2022 to January 2023. Patients were divided into two groups according to clinical indicators: common group (n = 48) and severe group (n = 20). The general condition, clinical symptoms, co-morbidity were analyzed. Coagulation index: D-dimer, plasma fibrinogen degradation products (FDP), plasma fibrinogen (Fib), prothrombin time (PT), activated partial thromboplastin time (APTT) and thrombin time (TT) were measured.   Results  The study confirmed that D-dimer and FIB were prolonged in both the common and severe groups; D-dimer and FDP in severe group were significantly longer than those in common group (P < 0.05). The proportion of patients with increased D-dimer and prolonged APTT and PT in severe group was higher than that in common group (P< 0.05) .   Conclusion  Monitoring coagulation parameters in elderly patients is helpful for clinical evaluation of the outcome or progression of the disease.
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