Effects of AVAPS-AE Mode of Non-invasive Ventilation on PSG Parameters，ESS Score and Comfort in Patients with AECOPD and OSA

Maoliang TIAN; Boxue HAN; Jiamei WANG; Zheng ZONG; Zhiping DENG

doi:10.12259/j.issn.2095-610X.S20240415

Volume 45 Issue 4

Apr. 2024

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Article Navigation > Journal of Kunming Medical University > 2024 > 45(4): 105-112

Maoliang TIAN, Boxue HAN, Jiamei WANG, Zheng ZONG, Zhiping DENG. Effects of AVAPS-AE Mode of Non-invasive Ventilation on PSG Parameters，ESS Score and Comfort in Patients with AECOPD and OSA[J]. Journal of Kunming Medical University, 2024, 45(4): 105-112. doi: 10.12259/j.issn.2095-610X.S20240415

Citation:

Maoliang TIAN, Boxue HAN, Jiamei WANG, Zheng ZONG, Zhiping DENG. Effects of AVAPS-AE Mode of Non-invasive Ventilation on PSG Parameters，ESS Score and Comfort in Patients with AECOPD and OSA[J]. Journal of Kunming Medical University, 2024, 45(4): 105-112. doi: 10.12259/j.issn.2095-610X.S20240415

Citation:

Maoliang TIAN, Boxue HAN, Jiamei WANG, Zheng ZONG, Zhiping DENG. Effects of AVAPS-AE Mode of Non-invasive Ventilation on PSG Parameters，ESS Score and Comfort in Patients with AECOPD and OSA[J]. Journal of Kunming Medical University, 2024, 45(4): 105-112. doi: 10.12259/j.issn.2095-610X.S20240415

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Effects of AVAPS-AE Mode of Non-invasive Ventilation on PSG Parameters，ESS Score and Comfort in Patients with AECOPD and OSA

doi: 10.12259/j.issn.2095-610X.S20240415

1.
Dept. of Respiratory and Critical Care Medicine，Zigong 1st People’s Hospital，Zigong Sichuan 643000
2.
Respiratory Department，General Hospital of Rocket Army，Beijing 100000，China

Received Date: 2023-09-20
Available Online: 2024-04-07
Publish Date: 2024-04-29

Abstract

Abstract

Objective To investigate the effects of non-invasive ventilation in mean volumetric pressure support and automatic expiratory pressure （AVAPS-AE） mode on multichannel sleep monitoring （PSG） parameters, Epworth sleepiness Scale （ESS） score and comfort in patients with acute exacerbation of chronic obstructive pulmonary disease （AECOPD） complicated with obstructive sleep apnea （OSA）. Methods 75 patients with AECOPD complicated with OSA in our hospital from January 2020 to October 2022 were randomly divided into 3 groups, each with 25 cases, all of which were treated with non-invasive ventilation. Control group A was treated with AVAPS mode, control group B was treated with S/T mode, and observation group was treated with AVAPS-AE mode. Blood gas analysis indexes [arterial partial pressure of oxygen （PaO₂）, arterial blood pH （pH）, arterial partial pressure of carbon dioxide （PaCO₂）], PSG parameters [arousal index （MAI）, apnea hypopnea index （AHI）, minimum pulse oxygen saturation （miniSpO₂）, sleep efficiency （TST/TRT）] and genioglossus muscle of the three groups were compared The variables of GGEMG （tonic, peak and phasic GGEMG during wakefulness and sleep NREM）, the incidence of man-machine confrontation, the rate of intubation at 48 hours, ESS, Brog, visual analogue scale （VAS） and health-related quality of life （HRQL） scores were compared before treatment and after 24, 48 and 72 hours of treatment. Results After 24 h, 48 h and 72 h treatment, PaO₂ groups were compared: observation group > control group A > control group B （P < 0.05）. Comparison between PaCO₂ groups: observation group < control group A < control group B （P < 0.05）. Comparison of TST/TRT and miniSpO₂ groups: observation group > control group A > control group B （P < 0.05）. Comparison between AHI and MAI groups: observation group < control group A < control group B （P < 0.05）. Comparison of tension, peak value and phase GGEMG between awake and NREM sleep groups: observation group < control group A < control group B （P < 0.05）. There was no significant difference in the incidence of man-machine confrontation and 48-h intubation rate among 3 groups （P> 0.05）. ESS, Brog and VAS were compared between groups: observation group < control group A < control group B （P < 0.05）; Comparison of HRQL among groups: observation group > control group A > control group B （P < 0.05）. Conclusion AVAPS-AE mode of non-invasive ventilation for AECOPD combined with OSA is beneficial to improve sleep, reduce daytime sleepiness, relieve dyspnea, and improve breathing comfort and quality of life.
- Noninvasive ventilation,
- OSA,
- AECOPD,
- AVAPS-AE,
- PSG,
- ESS

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