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Citation: Jianyu MAO, Jianjun CHEN, Jingnan YAN, Quan WANG, Li ZHAN, Shiqiao LI, Wenli BAO. The Clinical Effect of Ultrasound-guided Intercostal Nerve Pulsed Radiofrequency on the Treatment of Postherpetic Neuralgia at the Upper Thoracic Segment[J]. Journal of Kunming Medical University, 2024, 45(5): 88-93. doi: 10.12259/j.issn.2095-610X.S20240514

The Clinical Effect of Ultrasound-guided Intercostal Nerve Pulsed Radiofrequency on the Treatment of Postherpetic Neuralgia at the Upper Thoracic Segment

doi: 10.12259/j.issn.2095-610X.S20240514
  • Received Date: 2024-01-13
    Available Online: 2024-04-30
  • Publish Date: 2024-05-31
  •   Objective  To evaluate the clinical effect of ultrasound-guided intercostal nerve pulsed radiofrequency on the treatment of postherpetic neuralgia in the upper thoracic segment after herpes zoster infection.   Methods  A total of 67 patients with postherpetic neuralgia in the intercostal nerve of the thoracic region (segments 1, 2, and 3) and back region were included in this study. The patients were randomly assigned into an experimental group and a control group based on the type of treatment method. The experimental group consisted of 34 participants, including 15 males and 19 females, with an average age of (50.6±11.5) years. Pulsed radiofrequency procedure was performed on the intercostal nerves of segments 1, 2, and 3 under the ultrasound guidance for the subjects in the experimental group. The control group comprised 33 subjects, including 16 males and 17 females, with an average age of (51.5±12.7) years. Intercostal nerve block procedure was performed on segments 1, 2, and 3 under the ultrasound guidance for the patients in the control group. The visual analog scale (VAS) pain scores and Pain DETECT scale scores were compared before the treatment and 1, 3, 6, and 12 months after the treatment for the two groups. The recurrence rate of symptoms within 1 year after the treatment was determined and compared between the two groups.   Results  Complete follow-up was achieved in the 67 patients after the treatment, and the study subjects did not present with adverse reactions. The VAS pain scores and Pain DETECT scale scores at 1, 3, 6, and 12 months after the treatment were significantly better in the experimental group than in the control group (P < 0.05). The VAS pain scores and Pain DETECT scale scores at 1, 3, 6, and 12 months after the treatment were significantly improved compared with the pre-treatment scores for the two groups (P < 0.05). The recurrence rate of symptoms within 1 year after the treatment was significantly lower in the experimental group than in the control group (P < 0.05). These results showed that pulsed radiofrequency method was more effective for the treatment of postherpetic neuralgia in the upper thoracic segment after herpes zoster infection and had less adverse effects compared with the intercostal nerve block approach.   Conclusion  Ultrasound-guided intercostal nerve pulsed radiofrequency treatment is effective and safe for the treatment of postherpetic neuralgia in the upper thoracic segment after herpes zoster.
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