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Citation: Zhenkun YU, Kang LIU, Hua LIN, Beibei WANG, Hongming ZHANG, Jianming XIA. Individualized Numerical Simulation of Blood Flow in Stanford Type A Aortic Dissection[J]. Journal of Kunming Medical University, 2024, 45(6): 100-105. doi: 10.12259/j.issn.2095-610X.S20240613

Individualized Numerical Simulation of Blood Flow in Stanford Type A Aortic Dissection

doi: 10.12259/j.issn.2095-610X.S20240613
  • Received Date: 2024-02-24
    Available Online: 2024-05-23
  • Publish Date: 2024-06-25
  •   Objective   To investigate the hemodynamic changes after the occurrence of Stanford type A aortic dissection.   Methods   Computed tomography angiography(CTA) images of the aorta were collected from 4 Stanford A type aortic dissection patients and 2 healthy volunteers, and the three-dimensional models of the aorta were established and meshed. The above models were numerically simulated by fluid simulation software.   Results   The blood flow in the aorta of healthy volunteers was approximately laminar. The blood flow field in the true lumen was approximately laminar. Turbulence not only occurred near the intimal tear of the true lumen, but also near the area where the false lumen compressed the true lumen. The wall pressure of the true lumen was higher than that of the false lumen. During the systolic phase, the peak wall pressure of the false lumen was located at the primary entry tear of the dissection, the high wall shear stress appeared around the true lumen compressed by false lumen and the tear of false lumen. Moreover, stress concentration occurred at the intimal tear. Compared to aortic dissection with a single tear, aortic dissection with two tears exhibited lower wall shear stress around the intimal tear.   Conclusion   Individualized computational fluid dynamics analysis can provide reference for personalized diagnosis and treatment of aortic dissection.
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