Individualized Numerical Simulation of Blood Flow in Stanford Type A Aortic Dissection

Zhenkun YU; Kang LIU; Hua LIN; Beibei WANG; Hongming ZHANG; Jianming XIA

doi:10.12259/j.issn.2095-610X.S20240613

Volume 45 Issue 6

Jul. 2024

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Zhenkun YU, Kang LIU, Hua LIN, Beibei WANG, Hongming ZHANG, Jianming XIA. Individualized Numerical Simulation of Blood Flow in Stanford Type A Aortic Dissection[J]. Journal of Kunming Medical University, 2024, 45(6): 100-105. doi: 10.12259/j.issn.2095-610X.S20240613

Citation:

Zhenkun YU, Kang LIU, Hua LIN, Beibei WANG, Hongming ZHANG, Jianming XIA. Individualized Numerical Simulation of Blood Flow in Stanford Type A Aortic Dissection[J]. Journal of Kunming Medical University, 2024, 45(6): 100-105. doi: 10.12259/j.issn.2095-610X.S20240613

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Individualized Numerical Simulation of Blood Flow in Stanford Type A Aortic Dissection

doi: 10.12259/j.issn.2095-610X.S20240613

1.
Dept.of Cardiovascular Surgery，Fuwai Yunnan Cardiovascular Hospital，Kunming Yunnan 650102
2.
Dept.of Cardiovascular Surgery，Yan’an Hospital of Kunming City，Kunming Yunnan 650051
3.
Biomedical Engineering Research Institute of Kunming Medical University，Kunming Yunnan 650500
4.
Dept.of Cardiovascular Surgery，Changhai Hospital, Second Military Medical University，Shanghai 200082
5.
Kunming University of Science and Technology，Kunming Yunnan 650500，China

Received Date: 2024-02-24
Available Online: 2024-05-23
Publish Date: 2024-06-25

Abstract

Abstract

Objective To investigate the hemodynamic changes after the occurrence of Stanford type A aortic dissection. Methods Computed tomography angiography（CTA） images of the aorta were collected from 4 Stanford A type aortic dissection patients and 2 healthy volunteers, and the three-dimensional models of the aorta were established and meshed. The above models were numerically simulated by fluid simulation software. Results The blood flow in the aorta of healthy volunteers was approximately laminar. The blood flow field in the true lumen was approximately laminar. Turbulence not only occurred near the intimal tear of the true lumen, but also near the area where the false lumen compressed the true lumen. The wall pressure of the true lumen was higher than that of the false lumen. During the systolic phase, the peak wall pressure of the false lumen was located at the primary entry tear of the dissection, the high wall shear stress appeared around the true lumen compressed by false lumen and the tear of false lumen. Moreover, stress concentration occurred at the intimal tear. Compared to aortic dissection with a single tear, aortic dissection with two tears exhibited lower wall shear stress around the intimal tear. Conclusion Individualized computational fluid dynamics analysis can provide reference for personalized diagnosis and treatment of aortic dissection.
- Computational fluid dynamics,
- Hemodynamics,
- Numerical simulation,
- Aortic dissection

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References(17)

References

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