Analysis of Blood Cells and Establishment of Reference Interval of Elderly Derivative Index in Anning Area of Yunnan Province

Hong ZHU; Qiong DU; Zhengwei ZHAO; Liping CHEN; Muli XU; Yungui TU

doi:10.12259/j.issn.2095-610X.S20240620

Volume 45 Issue 6

Jul. 2024

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Hong ZHU, Qiong DU, Zhengwei ZHAO, Liping CHEN, Muli XU, Yungui TU. Analysis of Blood Cells and Establishment of Reference Interval of Elderly Derivative Index in Anning Area of Yunnan Province[J]. Journal of Kunming Medical University, 2024, 45(6): 145-153. doi: 10.12259/j.issn.2095-610X.S20240620

Citation:

Hong ZHU, Qiong DU, Zhengwei ZHAO, Liping CHEN, Muli XU, Yungui TU. Analysis of Blood Cells and Establishment of Reference Interval of Elderly Derivative Index in Anning Area of Yunnan Province[J]. Journal of Kunming Medical University, 2024, 45(6): 145-153. doi: 10.12259/j.issn.2095-610X.S20240620

Citation:

Hong ZHU, Qiong DU, Zhengwei ZHAO, Liping CHEN, Muli XU, Yungui TU. Analysis of Blood Cells and Establishment of Reference Interval of Elderly Derivative Index in Anning Area of Yunnan Province[J]. Journal of Kunming Medical University, 2024, 45(6): 145-153. doi: 10.12259/j.issn.2095-610X.S20240620

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Analysis of Blood Cells and Establishment of Reference Interval of Elderly Derivative Index in Anning Area of Yunnan Province

doi: 10.12259/j.issn.2095-610X.S20240620

Dept. of Anning City 1st People’s Hospital Clinical Laboratory，Anning Yunnan 650302，China

Received Date: 2024-01-21
Available Online: 2024-05-23
Publish Date: 2024-06-25

Abstract

Abstract

Objective To establish the derived indicators from blood cell analysis of the elderly in Anning region of Yunnan province, lymphocyte to monocyte ratio （LMR）, neutrophil to lymphocyte ratio （NLR）, platelet to lymphocyte ratio （PLR） reference interval, Observed differences from multicenter surveys, To determine the necessity to establish this reference interval. Methods The analysis results of people above 60 years old for physical examinations in the information system of Anning First People’ s Hospital from June 2022 to September 2022 were collected retrospectively. The biological reference interval for healthy elderly people in Anning City was established according to the indirect method in the international CLSI EP28-A3c guidelines. Results A total of 8877 cases were included. Red blood cell count （RBC）, hemoglobin （HGB）, hematocrit （HCT）, mean red blood cell hemoglobin concentration （MCHC）, platelet count （PLT）, and lymphocyte percentage （LYM%） decreased with age, and the difference between men and women was statistically significant （P < 0.05）. Only the broadband coefficient of variation of red blood cell volume distribution （RDWCV） increased with age. White blood cell count （WBC）, absolute value of neutrophils （NEU#）, absolute value of eosinophils （EOS#）, percentage of neutrophils （NEU%）, percentage of eosinophils （EOS%）, mean red cell volume （MCV）, standard deviation of red blood cell volume distribution width （RDWSD）, platelet volume distribution width （PDW） were statistically significant only between men and women （P < 0.05）, while the remaining items were not significant by age and sex （P > 0.05）. NLR increased with age, and men were significantly higher than women of the same age. Both LMR and PLR were higher in females than in males. Conclusion The results of WBC, RBC, HGB, PLT and HCT in the self-built reference interval were quite different from the reference interval of the multi-center survey.
- Elderly people,
- Neutrophil to lymphocyte ratio,
- Lymphocyte to monocyte ratio,
- Platelet to lymphocyte ratio,
- Reference interval

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References(38)

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