Analysis of Risk Factors Related to Female Infertility and Countermeasures

Yingjie YAO; Maohua QIN; Yunyan CHEN; Rongfang HUANG; Yunjie YANG; Nana LU; Haiqing WANG

doi:10.12259/j.issn.2095-610X.S20240916

Volume 45 Issue 9

Sep. 2024

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Article Navigation > Journal of Kunming Medical University > 2024 > 45(9): 103-109

Yingjie YAO, Maohua QIN, Yunyan CHEN, Rongfang HUANG, Yunjie YANG, Nana LU, Haiqing WANG. Analysis of Risk Factors Related to Female Infertility and Countermeasures[J]. Journal of Kunming Medical University, 2024, 45(9): 103-109. doi: 10.12259/j.issn.2095-610X.S20240916

Citation:

Yingjie YAO, Maohua QIN, Yunyan CHEN, Rongfang HUANG, Yunjie YANG, Nana LU, Haiqing WANG. Analysis of Risk Factors Related to Female Infertility and Countermeasures[J]. Journal of Kunming Medical University, 2024, 45(9): 103-109. doi: 10.12259/j.issn.2095-610X.S20240916

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Analysis of Risk Factors Related to Female Infertility and Countermeasures

doi: 10.12259/j.issn.2095-610X.S20240916

1.
Dept. of Reproductive Health and Infertility
2.
Grassroots Guidance Section，Kunming City Maternal and Child Health Hospital，Kunming Yunnan 650032，China

Received Date: 2024-05-06
Available Online: 2024-09-04
Publish Date: 2024-09-25

Abstract

Abstract

Objective To investigate the etiology and influencing factors of female infertility. Methods A total of 776 infertile women who visited Kunming Maternal and Child Health Hospital from July 2021 to June 2023 were collected. Multiple Logistic regression model was used to explore the etiology of infertility. Results The prevalence of female infertility is higher in the age group of 26～35 years old, and the etiology is complex and mutually influential, among which fallopian tube factors, ovulation disorders, and low ovarian reserve are the main reasons, accounting for 48.32%, 19.20%, and 10.57% of infertility patients respectively. For primary and secondary infertility patients, the P-values for the above three causes are <0.001, <0.001, and 0.42 respectively. Results from a multivariate logistic regression model suggest that age （95%CI: 1.14～1.21）, pre-pregnancy body mass index （BMI）（95%CI: 0.74～10.83, 1.28～2.30）, smoking history （95%CI: 1.27～17.66）, menstrual irregularities （95%CI: 3.52～8.68）, history of induced abortion （95%CI: 1.08-2.19, 5.52～15.22）, history of genitourinary tract infections （95%CI: 3.74～6.42）, and history of gynecological surgeries （95%CI: 3.99～7.40） are major influencing factors on female fertility. The primary cause of female infertility is tubal obstruction, which is associated with a history of unsafe sexual practices, abortions, and pelvic surgeries; secondary causes include ovulatory disorders, which are linked to diminished ovarian reserve, endocrine disorders, and delayed childbearing. Conclusion The main influencing factors of female infertility include tubal factors, ovulatory disorders, and decreased ovarian reserve function. Additionally, factors such as age, pre-pregnancy body mass index （BMI）, place of residence, smoking history, menstrual cycle regularity, number of induced abortions, history of genitourinary infections, history of gynecological surgeries, and systemic disease history all impact fertility. It is necessary to target the causes and influencing factors for proactive prevention and treatment.
- Fertility,
- Infertility,
- Risk factor,
- Prevention

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