A Clinical Analysis of BFMCs Vertebroplasty vs PKP in Treating Osteoporotic Vertebral Compression Fractures

Heng DING; Fan ZHANG; Yuan ZHANG; ZhenKai LOU; Hongkun LI; Yu LEI; Xingguo LI

doi:10.12259/j.issn.2095-610X.S20241011

Volume 45 Issue 10

Oct. 2024

Turn off MathJax

Article Contents

Article Navigation > Journal of Kunming Medical University > 2024 > 45(10): 67-74

Heng DING, Fan ZHANG, Yuan ZHANG, ZhenKai LOU, Hongkun LI, Yu LEI, Xingguo LI. A Clinical Analysis of BFMCs Vertebroplasty vs PKP in Treating Osteoporotic Vertebral Compression Fractures[J]. Journal of Kunming Medical University, 2024, 45(10): 67-74. doi: 10.12259/j.issn.2095-610X.S20241011

Citation:

Heng DING, Fan ZHANG, Yuan ZHANG, ZhenKai LOU, Hongkun LI, Yu LEI, Xingguo LI. A Clinical Analysis of BFMCs Vertebroplasty vs PKP in Treating Osteoporotic Vertebral Compression Fractures[J]. Journal of Kunming Medical University, 2024, 45(10): 67-74. doi: 10.12259/j.issn.2095-610X.S20241011

Citation:

Heng DING, Fan ZHANG, Yuan ZHANG, ZhenKai LOU, Hongkun LI, Yu LEI, Xingguo LI. A Clinical Analysis of BFMCs Vertebroplasty vs PKP in Treating Osteoporotic Vertebral Compression Fractures[J]. Journal of Kunming Medical University, 2024, 45(10): 67-74. doi: 10.12259/j.issn.2095-610X.S20241011

PDF( 1734 KB)

A Clinical Analysis of BFMCs Vertebroplasty vs PKP in Treating Osteoporotic Vertebral Compression Fractures

doi: 10.12259/j.issn.2095-610X.S20241011

Dept. Orthopedics，The 1st Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650032，China

Received Date: 2024-06-10
Available Online: 2024-10-12
Publish Date: 2024-10-31

Abstract

Abstract

Objective To explore the clinical efficacy of BFMC vertebroplasty versus PKP in treating OVCF. Methods A total of 290 patients diagnosed with OVCF at the First Affiliated Hospital of Kunming Medical University from September 2022 to November 2023 were selected, including 216 in the PKP group and 74 in the BFMCs group. All patients received regular osteoporosis treatment. Baseline data, surgical indexes, follow-up and imaging data were compared. Results There was no statistically significant difference between the two groups regarding age, gender, T-values, and the distribution of fractured vertebrae （P > 0.05）. All 290 patients successfully completed the surgery. Compared to the BFMCs group, there was no significant difference in operation durationand the amount of bone cement injected in the PKP group （P > 0.05）. The incidence of bone cement leakage in the BFMCs group was significantly lower than that in the PKP group （P < 0.05）, with 7 cases （9.50%） of leakage in the BFMCs group—3 cases in the anterior vertebral body and 4 cases in the intervertebral space; the PKP group had 85 cases （39.40%） of leakage, with 16 cases in the anterior vertebral body, 44 cases in the intervertebral space, 16 cases adjacent to the vertebral body, and 9 cases in the spinal canal （along the posterior longitudinal ligament）, all without neurological spine and cord symptoms. There was a statistically significant difference in the distribution type of the bone cement blocks post-surgery between the two groups （P <0.05）. All 290 patients were followed up for 6 months post-surgery. At the 1-month follow-up, the VAS scores of the BFMCs group were significantly better than those of the PKP group, with a statistically significant difference（P < 0.05）. At both the 1-month follow-up and the final follow-up, the ODI scores of the BFMCs group were significantly better than those of the PKP group, with statistically significant differences（P < 0.05）.VAS and ODI scores for both groups on the first day post-surgery, at 1 month post-surgery, and at the last follow-up were all significantly lower than pre-surgery, with statistically significant differences （P < 0. 05）. In terms of imaging, there were no statistically significant differences between the two groups regarding pre-surgery anterior edge height of the injured vertebrae, the vertebral body height recovery rate, and the Cobb angle of spinal kyphosis （P > 0.05）, but the anterior edge height of the injured vertebrae, the vertebral body height recovery rate, and the Cobb angle of spinal kyphosis showed improvement at the final follow-up compared to pre-surgery （P < 0.05）. Conclusion BFMCs and PKP have similar clinical efficacy in treating OVCFs; both effectively relieve patients’ symptoms and restore vertebral height. However, BFMCs significantly reduce cement leakage, making it a safe and effective option.
- Osteoporotic certebral compression fracture,
- Bone filling mesh container,
- Percutaneous kyphoplasty,
- Bone cement leakage,
- Vertebral body re-fracture

FullText(HTML)

References(21)

References

[1]	Park J S,Park Y S. Survival analysis and risk factors of new vertebral fracture after vertebroplasty for osteoporotic vertebral compression fracture[J]. Spine J,2021,21(8):1355-1361. doi: 10.1016/j.spinee.2021.04.022
[2]	Ji C,Rong Y,Wang J ,et al. Risk factors for refracture following primary osteoporotic vertebral compression fractures[J],Pain Physician,2021 ,24(3): E335-E340.
[3]	彭松林,何同忠,王尚,等. 骨质疏松性椎体压缩骨折经皮椎体后凸成形术后再骨折因素分析[J]. 中华骨与关节外科杂志,2020,13(12):987-990. doi: 10.3969/j.issn.2095-9958.2020.12.04
[4]	《中国老年骨质疏松症诊疗指南(2023)》工作组,中国老年学和老年医学学会骨质疏松分会,中国医疗保健国际交流促进会骨质疏松病学分会,等. 中国老年骨质疏松症诊疗指南(2023)[J]. 中华骨与关节外科杂志,2023,16(10):865-885.
[5]	康荘,唐可,肖艳,等. 核素骨显像和MRI定位骨质疏松性椎体压缩骨折责任椎体的价值[J]. 中华创伤杂志,2016,32(9):5.
[6]	井万里,张涛,滕东辉,等. 骨填充网袋椎体成形术治疗周壁破损型胸腰椎压缩性骨折预后不良分析[J]. 中国组织工程研究,2021,25(10):6.
[7]	王秀芝. 重度骨质疏松症患者预防跌倒及再骨折的护理干预[J]. 医药前沿,2016,6(19):305-306.
[8]	Kim YJ,Lee JW,Kim KJ,et al. Percutaneous vertebroplasty for intravertebral cleft: Analysis of therapeutic effects and outcome predictors[J]. Skeletal Radiol,2010,39(8):757-66. doi: 10.1007/s00256-009-0866-8
[9]	Chen Z,Chen Z,Wu Y,et al. Risk factors of secondary vertebral compression fracture after percutaneous vertebroplasty or kyphoplasty: A retrospective study of 650 patients[J]. Med Sci Monit,2019,25:9255-9261. doi: 10.12659/MSM.915312
[10]	Galibert P,Déramond H. Percutaneous acrylic vertebroplasty as a treatment of vertebral angioma as well as painful and debilitating diseases[J]. Chirurgie,1990,116(3): 326-34; discussion 335.
[11]	Lee I J ,Choi A L ,Yie M Y ,et al. CT evaluation of local leakage of bone cement after percutaneous kyphoplasty and vertebroplasty[J]. Acta Radiologica,2010,51(6): 649-654.
[12]	唐振坤,俞桂松,范奕松,等. 骨填充网袋椎体成形术与经皮椎体后凸成形术治疗骨质疏松性椎体压缩性骨折的Meta分析[J]. 中医正骨,2019,31(10):6.
[13]	吴宏梓,汪少波,拉华欠,等. 骨填充网袋术治疗骨质疏松性椎体压缩骨折疗效与安全性的Meta分析[J]. 中华创伤杂志,2020,36(5):9.
[14]	He CJ,Liu GD. Comparison of the efficacy and safety of bone-filling mesh container and simple percutaneous balloon kyphoplasty in the treatment of osteoporotic vertebral compression fractures[J]. Pain Physician,2018,21(3):259-268.
[15]	尹航,董博,康武林,等. 骨填充网袋椎体成形术和经皮椎体后凸成形术治疗骨质疏松性椎体压缩骨折的疗效对比[J]. 中华骨质疏松和骨矿盐疾病杂志,2022,(2):15.
[16]	姜树东,洪毅,张军卫,等. 网袋球囊椎体成形术治疗骨质疏松性脊柱骨折的早期临床疗效分析[J]. 中华骨与关节外科杂志,2018,11(9):5.
[17]	Ding J,Zhang Q,Zhu J,et al. Risk factors for predicting cement leakage following percutaneous vertebroplasty for osteoporotic vertebral compression fractures[J]. Eur Spine J,2016,25(11):3411-3417. doi: 10.1007/s00586-015-3923-0
[18]	张保良,陈仲强. 椎体强化术后继发骨水泥渗漏类型及其危险因素的临床评价[J]. 中华骨科杂志,2021,41(5):9.
[19]	Zhang F,Zhao Q M,Ni X H,et al. Comparison of unilateral and bilateral puncture percutaneous kyphoplasty in the treatment of osteoporotic vertebral compression fractures[J]. Neurosciences (Riyadh),2021,26(3):236-241. doi: 10.17712/nsj.2021.3.20200138
[20]	洪泽亚,吴钒,梁德,等. 骨填充网袋技术在伴椎体内裂隙征的骨质疏松性椎体压缩骨折治疗中对骨水泥渗漏的影响[J]. 中华骨与关节外科杂志,2024,17(03):234-239. doi: 10.3969/j.issn.2095-9958.2024.03.07
[21]	Zhu S Y,Zhong Z M,Wu Q,et al. Risk factors for bone cement leakage in percutaneous vertebroplasty: A retrospective study of four hundred and eighty five patients[J]. Int Orthop,2016,40(6):1205-1210. doi: 10.1007/s00264-015-3102-2

Relative Articles(20)

Relative Articles

[1]	Xiaona ZHAI, Lin FANG, Yong LI, Fang YU, Qiuyan PEI, Ping WANG, Zuoming YANG. Role of Postural Reduction and Rehabilitation Guidance in the Treatment of Vertebral Osteoporotic Fractures by Vertebroplasty. Journal of Kunming Medical University, 2022, 43(6): 105-109. doi: 10.12259/j.issn.2095-610X.S20220602
[2]	Tai-bang CHEN, Sheng LU, Dong-qiang SU, Rong-mao SHI, Jing-long LIANG. Comparative Study of Two Surgical Procedures for Osteoporotic Delayed Vertebral Collapse. Journal of Kunming Medical University, 2021, 42(2): 124-129. doi: 10.12259/j.issn.2095-610X.S20210203
[3]	Chen Xu , Wang Fei , Zhang Chun Qiang , Guo Pei Yu , Wang Yi Zhou , Du Kai Li . . Journal of Kunming Medical University, 2020, 41(06): 72-76.
[4]	Yu-wei JI, Xin ZHAO, Jiang-li LU, Yi YANG, Wei TANG, Jian-lin JIAO. Effect of Osteoking on Bone Density and Bone Biomechanics of Tree Shrews in a Postmenopausal Osteoporotic Fracture Model. Journal of Kunming Medical University, 2020, 41(11): 7-11. doi: 10.12259/j.issn.2095-610X.S20201103
[5]	Yang Xiu Mei , Wang Gang , Huang Qing Qing , Wan Xiao Hong . . Journal of Kunming Medical University, 2019, 40(05): 91-95.
[6]	Li Li , Li Jin Tao , Guo Yu Qing , Wu Chao , Lu Jiang Li , Zeng Yue Qin , Jiao Jian Lin . . Journal of Kunming Medical University, 2019, 40(06): 6-10.
[7]	Lin Tao , Dai Yue E , Song Jun Mei , Zhang Han . . Journal of Kunming Medical University, 2019, 40(01): 82-86.
[8]	Zhang Ying , Lu Yu , Zhao Zhi , Li Tao , Bi Ni , Shi Zhi Yue , Wang Ying Song , Jie Jing Ming , Song Yue Ming , Chang Li Tao , Guan Shuai , Tang Lin Bo . . Journal of Kunming Medical University, 2019, 40(11): 63-68.
[9]	Li Qiang , Tao Qi Chang , Dai Jian Hao , Chang Bin . Clinical Efficacy of Interbody Fusion with Autogeneous Bone in the Treatment of Lumbar Spondylolisthesis. Journal of Kunming Medical University, 2017, 38(08): 86-89.
[10]	Li Jin Tao , Zheng Hong , Li Bo , Yuan Xin , Tang Wei , Zhao Hong Bin . Effects of Osteoking on Estradiol and Bone Metabolism of Tree Shrews with Osteoporotic Fracture. Journal of Kunming Medical University, 2017, 38(11): 15-18.
[11]	Li Tao , Ma Chao Xia , Xu Ming , Liang Hong Suo . . Journal of Kunming Medical University, 2017, 38(02): 14-18.
[12]	Liang Da Wei . Different Prostheses in Artificial Hip Replacement for Osteoporotic Femoral Neck Fracture in Elderly Patients. Journal of Kunming Medical University,
[13]	Yuan Tao . . Journal of Kunming Medical University,
[14]	Zhang Jin Yu . . Journal of Kunming Medical University,
[15]	Kong Wei Yun . . Journal of Kunming Medical University,
[16]	Kong Wei Yun . . Journal of Kunming Medical University,
[17]	Fu Qiu Xia . . Journal of Kunming Medical University,
[18]	Yuan Xiao Feng . . Journal of Kunming Medical University,
[19]	Song Chao . Percutaneous Kyphoplasty in the Treatment of Osteoporotic Vertebral Compression Fractures. Journal of Kunming Medical University,
[20]	Duan Hong . Treatment of Thoracolumbar Burst Fracture with Transpedicular Bone Grafting Technique. Journal of Kunming Medical University,