Volume 46 Issue 6
Jun.  2025
Turn off MathJax
Article Contents
Yunhui ZHANG, Xiaorong YANG, Xieqiao HE, Fameng LUO, Haiyan ZHANG. Analysis of Nutritional Risk Factors in Inflammatory Bowel Disease Patients[J]. Journal of Kunming Medical University, 2025, 46(6): 171-176. doi: 10.12259/j.issn.2095-610X.S20250622
Citation: Yunhui ZHANG, Xiaorong YANG, Xieqiao HE, Fameng LUO, Haiyan ZHANG. Analysis of Nutritional Risk Factors in Inflammatory Bowel Disease Patients[J]. Journal of Kunming Medical University, 2025, 46(6): 171-176. doi: 10.12259/j.issn.2095-610X.S20250622

Analysis of Nutritional Risk Factors in Inflammatory Bowel Disease Patients

doi: 10.12259/j.issn.2095-610X.S20250622
  • Received Date: 2024-12-03
  • Publish Date: 2025-06-25
  •   Objective  To understand the incidence of nutritional risk in IBD patients in Kunming City, and to analyze the influencing factors.  Methods  A total of 707 IBD patients who were hospitalized in the First Affiliated Hospital of Kunming Medical University from September 2016 to May 2024 were retrospectively enrolled. Patient general information, disease-related data, and laboratory examination results were collected. Nutritional risk screening was performed using the NRS2002 scale, with subjects divided into nutritional risk and no-nutritional risk groups. Among Crohn's disease (CD) patients, 110 were in the nutritional risk group and 85 in the no nutritional risk group. For ulcerative colitis (UC) patients, 146 were in the nutritional risk group and 366 in the no nutritional risk group. Statistical analysis was conducted on the collected data.   Results  The incidence of nutritional risk in IBD patients was 36.21%, with 56.41% for CD and 28.52% for UC. Statistical analysis showed that for CD patients, sleep, BMI, disease diagnosis age, and disease activity were influencing factors of nutritional risk (P < 0.05). For UC patients, influencing factors were BMI, disease activity, albumin (ALB), and erythrocyte sedimentation rate (ESR) (P < 0.05).   Conclusion  IBD patients have a high nutritional risk, with CD patients being more severely affected. The influencing factors of nutritional risk are complex. Medical personnel should conduct early nutritional risk screening for IBD patients to avoid adverse outcomes due to nutritional issues.
  • loading
  • [1]
    张文玉,马贤纵,谢惠,等. 炎症性肠病患者营养障碍的研究[J]. 胃肠病学和肝病学杂志,2024,33(6):641-645. doi: 10.3969/j.issn.1006-5709.2024.06.002
    [2]
    Jablonska B,Mrowiec S. Nutritional status and its detection in patients with inflammatory bowel diseases[J]. Nutrients,2023,15(8):1991. doi: 10.3390/nu15081991
    [3]
    Prieto J,Andrade A R,Magro D O,et al. Nutritional global status and its impact in crohn's disease[J]. J Can Assoc Gastroenterol,2021,4(6):290-295. doi: 10.1093/jcag/gwab006
    [4]
    王凤纤,缪应雷,张雪芹,等. 炎症性肠病的肠内营养治疗[J]. 临床消化病杂志,2020,32(2):132-136. doi: 10.3870/lcxh.j.issn.1005-541X.2020.02.16
    [5]
    Kondrup J,Rasmussen H H,Hamberg O,et al. Nutritional risk screening (NRS 2002): A new method based on an analysis of controlled clinical trials[J]. Clin Nutr,2003,22(3):321-336. doi: 10.1016/S0261-5614(02)00214-5
    [6]
    中华医学会消化病学分会炎症性肠病学组. 炎症性肠病诊断与治疗的共识意见(2018 年,北京)[J]. 中华消化杂志,2018,38(5):292-311. doi: 10.3760/cma.j.issn.0254-1432.2018.05.002
    [7]
    Best W R,Becktel J M,Singleton J W,et al. Development of a Crohn's disease activity index. National cooperative crohn's Disease study[J]. Gastroenterology,1976,70(3):439-444. doi: 10.1016/S0016-5085(76)80163-1
    [8]
    王海霞,王睿,魏文英,等. 用GLIM标准评估炎症性肠病营养不良及其影响因素[J]. 肠外与肠内营养,2022,29(4):218-225.
    [9]
    晏巍,黄亚娟,陈舒燕,等. 炎症性肠病患者发生营养风险的影响因素分析[J]. 齐鲁护理杂志,2023,29(19):39-42. doi: 10.3969/j.issn.1006-7256.2023.19.011
    [10]
    是子豪,赖苏奇,乔旦,等. 炎症性肠病营养风险和营养治疗方案选择的回顾性研究[J]. 医学信息,2021,34(24):90-92. doi: 10.3969/j.issn.1006-1959.2021.24.020
    [11]
    林茂伟. 炎症性肠病患者营养风险筛查及相关因素分析[J]. 临床合理用药杂志,2019,12(31):140-142.
    [12]
    张亚峰,王海燕,连晋梅,等. 从护理角度预防炎症性肠病的复发研究[J]. 循证护理,2021,7(18):2481-2483.
    [13]
    Smith R P,Easson C,Lyle S M,et al. Gut microbiome diversity is associated with sleep physiology in humans[J]. PLoS One,2019,14(10):e222394.
    [14]
    Doherty R,Madigan S,Warrington G,et al. Sleep and nutrition interactions: Implications for athletes[J]. Nutrients,2019,11(4):822. doi: 10.3390/nu11040822
    [15]
    Wang Y H,Wang J,Chen S H,et al. Association of longitudinal patterns of habitual sleep duration with risk of cardiovascular events and all-cause mortality[J]. JAMA Netw Open,2020,3(5):e205246. doi: 10.1001/jamanetworkopen.2020.5246
    [16]
    王冠军,杨锦茹,徐常杰,等. 深圳某三甲医院炎症性肠病患者GLIM标准诊断营养不良及其相关因素分析[J]. 中华临床营养杂志,2023,31(1):9-17. doi: 10.3760/cma.j.cn115822-20220901-00177
    [17]
    张俊. 活动期溃疡性结肠炎的营养风险筛查与危险因素分析[J]. 现代诊断与治疗,2023,34(2):251-253.
    [18]
    王凤纤,缪应雷,张晖敏,等. 372例住院活动期溃疡性结肠炎患者的营养风险筛查[J]. 中华炎性肠病杂志(中英文),2020,4(1):47-50.
    [19]
    Einav L,Hirsch A,Ron Y,et al. Risk factors for malnutrition among IBD patients[J]. Nutrients,2021,13(11):4098. doi: 10.3390/nu13114098
    [20]
    陈玲琳,浦菊芬,孙莉. 改良营养不良通用筛查工具在炎症性肠病患者中的应用研究[J]. 中国医药科学,2024,14(9):195-198.
    [21]
    Gold S L,Rabinowitz L G,Manning L,et al. High prevalence of malnutrition and micronutrient deficiencies in patients with inflammatory bowel disease early in disease course[J]. Inflamm Bowel Dis,2023,29(3):423-429. doi: 10.1093/ibd/izac102
    [22]
    楚俊红,王丽敏,樊虹雨,等. 活动期溃疡性结肠炎住院病人营养风险研究[J]. 护理研究,2022,36(22):4131-4133. doi: 10.12102/j.issn.1009-6493.2022.22.036
    [23]
    王荣玉. 炎症性肠病患者营养状况与生存质量分析[D]. 青岛: 青岛大学,2019.
    [24]
    莫彦. 克罗恩病患者营养状态与掌诊特征的相关性研究[D]. 广州: 广州中医药大学,2023.
    [25]
    中华医学会消化病学分会炎症性肠病学组,中华医学会肠外与肠内营养学分会胃肠病与营养协作组. 炎症性肠病营养支持治疗专家共识(第二版)[J]. 中华炎性肠病杂志(中英文),2018,2(3):154-172.
    [26]
    Rabbani G,Ahn S N. Structure,enzymatic activities,glycation and therapeutic potential of human serum albumin: A natural cargo[J]. Int J Biol Macromol,2019,123:979-990. doi: 10.1016/j.ijbiomac.2018.11.053
    [27]
    唐琬茹. 炎症性肠病住院患者营养状况的评价及与疾病进展的相关性研究[D]. 沈阳: 中国医科大学,2022.
  • Relative Articles

    [1] Qianrong YANG, Xue CAO, Jiao YANG, Yanqiu ZHAO, Nan SHEN, Yajiao SUN. Status and Influencing Factors of Stigma in Lung Cancer Patients. Journal of Kunming Medical University, 2025, 46(1): 60-67.  doi: 10.12259/j.issn.2095-610X.S20250108
    [2] Qingbo WANG, Ziyang QIAO, Zhiping ZHAO, Wenqi SONG, Zhiyan SI. Therapeutic Effects and Mechanisms of Emodin on Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice. Journal of Kunming Medical University, 2025, 46(9): 72-80.  doi: 10.12259/j.issn.2095-610X.S20250908
    [3] Hanyu ZHANG, Juan LUO, Mingzhi DONG, Qiyin CHEN, Fengrui ZHANG, Rui GUO, Junying TONG, Yinglei MIAO. Retrospective Cohort Study of Infliximab and Vederizumab in the Treatment of Moderate-to-severe Ulcerative Colitis. Journal of Kunming Medical University, 2025, 46(4): 1-9.
    [4] Bo TIAN, Yongmei JIN, Haiwen LI, Chongxi LI, Wei ZHANG, Wei GUAN, Haiyun CHEN, Qi XUE, Huirong YANG, Jun LIU. Analysis of the Current Status and Influencing Factors of Metabolic Syndrome in Patients Undergoing Antiretroviral Therapy for AIDS. Journal of Kunming Medical University, 2024, 45(11): 149-154.  doi: 10.12259/j.issn.2095-610X.S20241121
    [5] Shumei QIU, Jingrui YANG, Xuecai QIU. The Risk and Influencing Factors of Vascular Dementia in Middle-aged and Elderly People in Kunming. Journal of Kunming Medical University, 2024, 45(9): 91-96.  doi: 10.12259/j.issn.2095-610X.S20240914
    [6] Hanyu ZHANG, Juan LUO, Mingzhi DONG, Qiyin CHEN, Fengrui ZHANG, Rui GUO, Junying TONG, Yinglei MIAO. Retrospective Cohort Study of Infliximab and Vederizumab in the Treatment of Moderate-to-severe Ulcerative Colitis. Journal of Kunming Medical University, 2024, 45(10): 36-44.  doi: 10.12259/j.issn.2095-610X.S20241006
    [7] Chunling LI, Linghua LI, Xu HAN, Jie YANG, Heng ZHANG. Clinical Observation of Treating Ulcerative Colitis with Acupuncture at Front Mu Points Combined with Oral Mesalazine. Journal of Kunming Medical University, 2024, 45(3): 72-78.  doi: 10.12259/j.issn.2095-610X.S20240311
    [8] Zhangqin LI, Qi HUANG, Yinglei MIAO. Research Progress on Paradoxical Extraintestinal Manifestations of Biologics in the Treatment of Inflammatory Bowel Disease. Journal of Kunming Medical University, 2024, 45(2): 160-165.  doi: 10.12259/j.issn.2095-610X.S20240223
    [9] Bo LI, Yang SUN, Yinglei MIAO. Intestinal Microecological Changes and Therapeutics in Inflammatory Bowel Disease. Journal of Kunming Medical University, 2024, 45(4): 1-8.  doi: 10.12259/j.issn.2095-610X.S20240401
    [10] Zhongshun NIE, Yinglei MIAO. Prospects of Fecal Microbiota Transplantation for Inflammatory Bowel Disease in the Context of Biological Agents. Journal of Kunming Medical University, 2024, 45(10): 147-154.  doi: 10.12259/j.issn.2095-610X.S20241023
    [11] Meizi RAO, Xinyi JIANG, Jiarong MIAO. Analysis of Risk Factors for Co-Infection of Ulcerative Colitis with Epstein-barr Virus and Cytomegalovirus. Journal of Kunming Medical University, 2024, 45(11): 87-94.  doi: 10.12259/j.issn.2095-610X.S20241113
    [12] Yanqin RUAN, Maojuan LI, Limei HE, Ying SONG, Qiaoyun HUANG, Ying CHEN, Chang LIU. Screening of Special Abnormal Module Items in PRO Scale for Patients with Inflammatory Bowel Disease.. Journal of Kunming Medical University, 2022, 43(3): 37-43.  doi: 10.12259/j.issn.2095-610X.S20220310
    [13] Rong LIU, Yang SUN, Fameng LUO, Dezhi TAO, Haiyan ZHANG. Correlation between the Acceptance of Illness and Quality of Life in Patients with Inflammatory Bowel Disease. Journal of Kunming Medical University, 2022, 43(5): 173-178.  doi: 10.12259/j.issn.2095-610X.S20220507
    [14] Xiaolin LIU, Xiaocui CHEN, Yang SUN, Minli LI, Yinglei MIAO. Clinical Efficacy and Safety Evaluation of Fecal Bacteria Transplantation by Different Ways on Ulcerative Colitis. Journal of Kunming Medical University, 2022, 43(6): 46-51.  doi: 10.12259/j.issn.2095-610X.S20220612
    [15] Yong-li WANG, Qi WU, Jian-pei SU, Yu-wen LIU, Zhi-min WANG, Feng-yun LUO, Wei-meng TIAN. Correlation between Depressive State and Health Status of the Elderly with Chronic Disease and Intervention Outcomes. Journal of Kunming Medical University, 2021, 42(12): 135-139.  doi: 10.12259/j.issn.2095-610X.S20211233
    [16] Zhang An Xing , Wu Jing , Sun Yang , Miao Ying Lei . . Journal of Kunming Medical University, 2018, 39(09): 128-132.
    [17] Bi Hong . The Analysis of Influential Factors of Pulmonary Function in Patients with Chronic Obstructive Pulmonary Disease in Kunming. Journal of Kunming Medical University,
    [18] Chen Xiao Hong . Influence of Continuous Nursing Intervention on Psychological Quality and Medication Compliance in Ulcerative Colitis Patients after Discharge. Journal of Kunming Medical University,
    [19] Li Hong Li . . Journal of Kunming Medical University,
    [20] Ai Jia . . Journal of Kunming Medical University,
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(6)

    Article Metrics

    Article views (317) PDF downloads(17) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return