Yang Li Li . Polarized Solution Treatment and Sodium Bicarbonate on Hyperkalemia in Rabbits[J]. Journal of Kunming Medical University, 2011, 32(12).
Citation: Yang Li Li . Polarized Solution Treatment and Sodium Bicarbonate on Hyperkalemia in Rabbits[J]. Journal of Kunming Medical University, 2011, 32(12).

Polarized Solution Treatment and Sodium Bicarbonate on Hyperkalemia in Rabbits

  • Objective To investigate a steady way which named“intravenously guttae”of preparation of hyperkalemia in rabbit,and compare two different treatment methods polarized solution treatment and sodium bicarbonate treatment.Methods 30 rabbits were randomly divided into 3 groups:Saline group,polarized solution(glucose-insulin)group and sodium bicarbonate group(n=10 in each group).All rabbits were injected with 3% KCl and were treated with different ways.Results  Typical ECG changes were found,and serum levels of [K+]were increased(P<0.05)in all 30 rabbits in three groups after injection of 3% KCL.After treatment,compared with Saline group,serum levels of [k+] were decreased significantly (P<0.05)and ECG recovered to normal in glucose-insulin group and sodium bicarbonate group.Conclusion  “Intravenously guttae”is a simple and steady way of preparation of hyperkalemia model. Glucose-insulin and sodium bicarbonate are effective methods for the treatment of hyperkalemia.
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