［Abstract］Objective　To evaluate the therapeutic effect of Pingyangmycin and lipiodol emulsion（PLE） embolization for cavernous hemangioma of liver（CHL）．Methods　We analyzed the clinical data of the 42 cases of the CHL treated by selectively injecting pingyangmycin lipiodol emulsion（PLE）into the supplying artery of tumors，and the patients were followed up after the operation for 6 months to 12 months．Results　All the 42 patients were performed successfully with Hepatic artery intubation and 17 of these patients were performed with super selectively sent into the supplying artery of tumors．The embolism times was(1.3±1.1)/person for 5～10 cm CHL，(2.8±2.2)/person for 10～20 cm and (3.3±2.3)/person for 21～30 cm．Followed up 6 months to 18 months，CHL reduced by over 50％ in 4 cases，and reduced by 25％~50％ in 31 cases，and reduced less than 25% in 6 cases，respectively．But one case didn't appear clinical effect． There were no serious complications．Conclusion　It is reliable and feasible that treating CHL with PLE through super selective hepatic artery intubation