Wang Xiao Li . The Curative Effect of Nedaplatin Concurrent Chemotherapy and Radiotherapy on Local Advanced Cervical Cancer[J]. Journal of Kunming Medical University, 2012, 33(10).
Citation: Wang Xiao Li . The Curative Effect of Nedaplatin Concurrent Chemotherapy and Radiotherapy on Local Advanced Cervical Cancer[J]. Journal of Kunming Medical University, 2012, 33(10).

The Curative Effect of Nedaplatin Concurrent Chemotherapy and Radiotherapy on Local Advanced Cervical Cancer

  • [Abstract]Objective To investigate the effect and toxicity of nedaplatin concurrent chemotherapy and radiotherapy on local advanced cervical Cancer.Methods The nedaplatin was given at a dose of 30 mg(m2.w) once a week for 5 weeks in 35 patients. External radiotherapy was given at a dose 30 Gy firstly and then was irradiated for another 20 Gy under the condition of A point by linear accelerator 6Mev-X, the total radiotherapy dose was 50 Gy. From the 4th week post radiotherapy, intracavitary irradiation at DT 600cGy/time was given for twice a week, and lasted for 7 times to a total dose 4 200 cGy for A point. The curative effect and adverse reactions were observed.Results The total effective rate and clinical benefits rate were both 89%.The 24 months disease-free survival and overall survival rate was 80%and 94%, respectively.Conclusion Nedaplatin concurrent chemotherapy and radiotherapy can get better effects and tolerated side-effects
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