The Relationship between Thyroid Hormone and Purine Metabolism and Body Weight in Patients with Type II Diabetes and Normal Thyroid Function

Han Wen Ju; Niu Ben; Liang Yun; Duan Xiao Yan; Su Heng; Xue Yuan Ming

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Han Wen Ju , Niu Ben , Liang Yun, Duan Xiao Yan , Su Heng , Xue Yuan Ming . The Relationship between Thyroid Hormone and Purine Metabolism and Body Weight in Patients with Type II Diabetes and Normal Thyroid Function[J]. Journal of Kunming Medical University, 2016, 37(11): 82-85.

Citation:

Han Wen Ju , Niu Ben , Liang Yun, Duan Xiao Yan , Su Heng , Xue Yuan Ming . The Relationship between Thyroid Hormone and Purine Metabolism and Body Weight in Patients with Type II Diabetes and Normal Thyroid Function[J]. Journal of Kunming Medical University, 2016, 37(11): 82-85.

Citation:

Han Wen Ju , Niu Ben , Liang Yun, Duan Xiao Yan , Su Heng , Xue Yuan Ming . The Relationship between Thyroid Hormone and Purine Metabolism and Body Weight in Patients with Type II Diabetes and Normal Thyroid Function[J]. Journal of Kunming Medical University, 2016, 37(11): 82-85.

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The Relationship between Thyroid Hormone and Purine Metabolism and Body Weight in Patients with Type II Diabetes and Normal Thyroid Function

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基金：云南省卫生科技内设研究机构项目(2014NS257);

Received Date: 2016-05-17

Abstract

Abstract

Objective To investigate the relationship between thyroid hormone and uric acid(UA) and body mass index(BMI) in patients with type II diabetes and normal thyroid function. Methods Total of 313 patients with type II diabetes and normal thyroid function were selected. BMI, fasting blood glucose(FBG),the metabolism of blood lipid, thyroid hormones and UA indicators were examined and the correlations of thyroid hormone,BMI and UA were analyzed.Results(1) The patients were divided into two groups according to gender,and FT3, FT4, and UA of male were found to be significantly higher than those in female(P<0.01). TSH,SBP,HDL-C in female were significantly higher than those in male(P<0.01);(2) The patients were divided into three groups according to BMI level. Thyroid-stimulating hormone(TSH),three iodine armour gland original glycine(TT3), free three iodine thyroid glycine(FT3), UA,and FBG in overweight and obesity groups were found to be higher than those in normal weight group(P < 0.05);(3) The patients were divided into two groups according to the TSH level. Serum uric acid,TT3,FT3,fasting insulin in the group with TSH above 2.5 u IU/L were found to be higher than those in the group with TSH under 2.5 u IU/L(P < 0.05);(4) Patients were divided into two groups according to the UA level. TSH, FT3 in male with high uric acid were found to be higher than those in male with normal uric acid(P < 0.05);TSH was in female with high uric acid was found to be higher than that in female with normal uric acid(P < 0.05). Conclusion Thyroid hormone in patients with type II diabetes can be used to assess the body weight and uric acid, which is of great clinical importance.
- Type II diabetes,
- Thyroid hormone,
- Body mass index,
- Uric acid

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References(9)

References

[1]	[1]TAKASHIMA N,NIWA Y,MANNAMI T,et al.Characterization of subclinical thyroid dysfunction from cardiovascular and metabolic viewpoints:the Suita study[J].Circ J,2007,71(2):191-195.
[2]张梦媛,任安.不同性别2型糖尿病患者甲状腺功能与血脂关系分析[J].中国临床保健杂志,2014,17(1):21-24.
[3]中华医学会内分泌学分会,高尿酸血症和痛风治疗的中国专家共识[J].中华内分泌代谢杂志,2013,29(11):913.
[4]王有菊,史虹莉.甲状腺激素和年龄相关性研究[J].中国临床保健杂志,2008,11(1):51-53.
[5]姚武位,陈庆伟,柯大智.高密度脂蛋白胆固醇和冠心病的相关性研究[J].重庆医科大学学报,2009,34(11):1510-1513.
[6]张皎月,陈璐璐,孙晖,等.正常人群甲状腺功能与脂肪代谢的相关性分析[J].中国糖尿病杂志,2013,21(3):214.
[7]余利虹,朱麒钱.2型糖尿病患者糖脂代谢与血清甲状腺激素相关性分析[J].中国糖尿病杂志,2012,20(5):263-266.
[8]钟建庭,王璇,赵玲,等.亚临床甲状腺功能减退脂代谢、糖代谢和尿酸代谢的变化[J].中国误诊学杂志,2009,9(30):7367-7368.
[9]	[9]RUHLA S,WEICKERT M O,ARARAT A M,et al.A high normal TSH is associated with the metabolic syndrome[J].Clin Endocrinol(Oxf),2010,72(5):696-701.

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