Volume 37 Issue 12
. 
Turn off MathJax
Article Contents
Abstract
References
Relative Articles
Article Navigation >  Journal of Kunming Medical University  > 2016  >  37(12): 103-106
Li Quan , Zhang Yuan , Liang Yue Wei , Ruan Rui , Zhao Xue Ling , Xie Shi Wei , Zhang Lin . Research Progress of Cerebrospinal Fluid Leakage in Lumbar Spine Surgery[J]. Journal of Kunming Medical University, 2017, 38(09): 129-133.
Citation: Zhou Yi Jiao , Hu Ping , Jiao Shu Lan , Zhao Ning Hui , Yang Lu Yan , Chen Tian Zi . Comparison of Effects on Intraoperative Cerebral Metabolism between Total Intravenous Anesthesia and Intravenous Inhalation Anesthesia in Patients in Neurosurgery[J]. Journal of Kunming Medical University, 2016, 37(12): 103-106.
shu

Comparison of Effects on Intraoperative Cerebral Metabolism between Total Intravenous Anesthesia and Intravenous Inhalation Anesthesia in Patients in Neurosurgery

Funds:

基金： 云南省医学学科带头人基金资助项目(D-201221); 昆明医科大学硕士研究生创新基金资助项目(2015S97);

  • Received Date: 2016-07-10
    Abstract
  • Objective To compare the effect on intraoperative cerebral metabolism between the propofol combined with remifentanil infusion in total intravenous anesthesia and the desflurane combined with remifentanil intravenous inhalation anesthesia in patients in neurosurgery.Methods Thirty-four patients were randomly divided into the propofol combined with remifentanil group(group A,n=16) and the desflurane combined withremifentanil group(group B,n=18).The B-ultrasound under the guide of retrograde catheterization through right internal jugular vein and artery was prepared after the patients entered the operation room.Atropine,propofol,fentanyl, rocuronium were used in the induction of anesthesia.The mechanical ventilation was applied after conventional trachea cannula.Once patients were anesthetized steadily, jugular bulb venous oxygen saturation(Sjv O),jugular2 bulb venous oxygen partial pressure(Pjv O),Jugular2 Bulb venous hemoglogin(Hbv),jugular bulb venous lactate(Ljv),jugular bulb venous gluxose(Gv),arterial oxygen saturation(Sa O),arterial2 oxygen pressure(Pa O2),arterin(Hba),arterial blood lactate(La),arterial blood gluxose(Ga),arterial blood oxygen content(Ca O2), jugular bulb venous oxygen content(Cjv O2), arteriovenous oxygen difference(AVDO2),cerebral extraction of oxygen(CEO2),cerebral lactate production rate(CLP) and cerebral glucose uptake rate(CGU) at different time [before anesthesia induction(T1),1 hours after the start of the operation(T2),2 hours after the start of the operation(T3),half an hour after the operation]were collected.Results(1) The value of Sjv O2,Pjv O2,Cjv O2 and Ca O2 in group B was significantly higher than that in group A(P<0.001);The value of AVDO2 and CEO2in group B was lower than that in group A(P<0.05);(2) The value of Gv and Ga in group B was higher than that in group A(P<0.05);There were no significant differences about CGU in two groups(P>0.05);(3) The value of CLP in group B was lower than that in group A(P<0.05);there were no significant differences about Ljv and La in two groups(P>0.05);(4) Compared with the value at moment of T1 between group A and group B,the value of Pa O2,Sa O2,Pjv O2 and Sjv O2 were increased with time(P<0.05),the value of Ca O2, Cjv O2, AVDO2 and CEO2showed a downward trend(P <0.05).Conclusion(1) Both total intravenous anesthesia and intravenous inhalation anesthesia can reduce the cerebral oxygen metabolism;(2) For the cerebral protection of neurosurgery operation,it seems that the effect of intravenous inhalation anesthesia is more stronger than total intravenous anesthesia.
    • FullText(HTML)
    • References(15)
  • [1]王龙,胡晓.神经重症监护室内监测技术研究进展[J].实用医学杂志,2015,31(1):157-158.
    [2]侯景利,徐世元,刘合年,等.异丙酚或异氟醚用于妇科腹腔镜手术时脑氧供需平衡的变化[J].临床麻醉学杂志,2009,25(4):303-305.
    [3]吕旭华,胡建.芬太尼与舒芬太尼在神经外科手术麻醉中的应用对比[J].中国实用神经疾病杂志,2014,17(5):76-78.
    [4]
    [4]HOLZER A,WINTER W,GREHER M.A comparison of propofol and sevoflurane anesthesia:Effects on aortic blood flow velocity and middle cerebral artery blood flow velocity[J].Anaesthesia,2003,58(3):217-222.
    [5]王晓军.丙泊酚与咪达唑仑在急性脑出血手术中的应用效果对比[J].四川医学,2015,36(2):210-212.
    [6]王海英,喻田.神经外科手术的围术期脑保护[J].遵义医学院学报,2005,28(6):572-574.
    [7]许立新,佘守章,许学兵.芬太尼对地氟醚麻醉效应的影响[J].中华麻醉学杂志,2000,20(2):116-117.
    [8]
    [8]SAIDMAN L J.The rate of desflurane in the plactice of anesthesia[J].Anesthesiology,1991,74(3):399.
    [9]
    [9]GHONEIM A A,AZER M S,GHOBRIAL HZ,et al.Awakening properties of isoflurane,sevoflurane,and desflurane in pediatric patients after craniotomy for supratentorial tumours[J].J Neurosurg Anesthesiol,2015,27(1):1-6.
    [10]任占杰,张成明,黄爱杰,等.吸入麻醉药发展历程中的哲学思维[J].当代医学,2009,15(7):67-68.
    [11]杨丹,余庆波,万勇.右美托咪定与瑞芬太尼在声带息肉摘除术中的应用比较[J].川北医学院学报,2015,30(2):187-190.
    [12]杨娟,角述兰,黄瑞萍,等.瑞芬太尼复合丙泊酚在清醒开颅手术中的应用[J].昆明医科大学学报,2014,35(6):55-57.
    [13]王建君,周立平,吴达,等.重型颅脑损伤患者早期血乳酸与乳酸清除率的临床意义[J].江苏医药,2014,40(22):2697-2699.
    [14]林蓉,张富平.局部脑氧饱和度监测在术后认知功能障碍方面的应用[J].医学研究生学报,2010,23(1):102-104.
    [15]
    [15]SOUSTIEL J F,SVIRI G E,MAHAMID E,et al.Cerebral blood flow and metabolism following decompressive craniectomy for control of increased intracranial pressure[J].Neurosurgery,2010,6(71):65-72.
    • Relative Articles(20)

  • Relative Articles

    [1] Ying TAN, Haiyan QIN, Xiang SUN, Yanyi SU, Yingbao WANG. Propofol Regulates MPP+-induced Mitochondrial Oxidative Stress and Apoptosis in SH-SY5Y Cells. Journal of Kunming Medical University, 2024, 45(3): 35-41.  doi: 10.12259/j.issn.2095-610X.S20240305
    [2] Keyan WANG, Bingting LIN, Xiaolin WENG, Bin HUANG, Lie WANG. Effectiveness and Safety Analysis of Cyclopol Combined with Remifentanil in Anesthesia for Endoscopic Gastric Cancer Radical Surgery. Journal of Kunming Medical University, 2024, 45(6): 154-160.  doi: 10.12259/j.issn.2095-610X.S20240621
    [3] Ningli ZHANG, Chen ZHOU, Yongyu SI, Jie OUYANG, Lan LIN, Ying CHEN, Qin NIU, Hong LI. Clinical Application of Esketamine Combined with Propofol in Painless Abortion. Journal of Kunming Medical University, 2023, 44(5): 102-106.  doi: 10.12259/j.issn.2095-610X.S20230514
    [4] Dongyang ZHANG, Zheng LI, Yahong WANG, Guangshun LIU, Yuhang QUAN, Xiang MA. Analysis of Subanesthetic Doses of Esketamine and Propofol in Three-dimensional Afterloading Treatment of Cervical Cancer. Journal of Kunming Medical University, 2023, 44(7): 113-118.  doi: 10.12259/j.issn.2095-610X.S20230721
    [5] Juan LI, Jun ZHANG, Qiao-ling ZHENG, Pu-qiong FENG, Jin HE. Analysis of Monitoring Results and Influencing Factors of Vancomycin Blood Concentration in Neurosurgery Department. Journal of Kunming Medical University, 2021, 42(6): 110-114.  doi: 10.12259/j.issn.2095-610X.S20210614
    [6] Dan-ni ZHANG, Xia-guang DUAN, Chun-guang HAO, Xiao-jun ZHI, Hai-feng ZHU, Zai-qing HUANG. Anesthetic Effects and Mechanism of Hydromorphone Combined with Propofol on Colorectal Dilatation Model. Journal of Kunming Medical University, 2021, 42(7): 25-30.  doi: 10.12259/j.issn.2095-610X.S20210705
    [7] Wei Xing . . Journal of Kunming Medical University,
    [8] Zhang Mei Qiong . . Journal of Kunming Medical University,
    [9] Fang Yu . . Journal of Kunming Medical University,
    [10] Jiao Shu Lan . . Journal of Kunming Medical University,
    [11] Li Cui Lin . . Journal of Kunming Medical University,
    [12] Chang Qian . . Journal of Kunming Medical University,
    [13] Yao Yan Qiong . . Journal of Kunming Medical University,
    [14] Dai Zheng . . Journal of Kunming Medical University,
    [15] Fan Dan . . Journal of Kunming Medical University,
    [16] Ren Ling . . Journal of Kunming Medical University,
    [17] Chen Xue Qiang . . Journal of Kunming Medical University,
    [18] . . Journal of Kunming Medical University,
    [19] . . Journal of Kunming Medical University,
    [20] . . Journal of Kunming Medical University,
    • Supplements(0)
    • Cited By

  • Cited by

    Periodical cited type(5)

    1. 高慧，林锋，杨旭颖，黄涛，吴涛. mNGS在15例海南危重型立克次体病早期救治中的价值. 中华检验医学杂志. 2023(02): 137-142 .
    2. 蒋红双，李晓洁，李佳颖，邓敏华，雷卓青，黄婧渝. 恙虫病患者的临床特征分析. 中国医学创新. 2022(19): 75-79 .
    3. 李懿，贺志权，范威，马红霞，黄学勇. 恙虫病患者血清细胞因子水平研究. 河南预防医学杂志. 2021(07): 485-488 .
    4. 李瑜珍. 阿奇霉素与氯霉素治疗恙虫病的临床效果对比研究. 世界复合医学. 2021(07): 164-166 .
    5. 文韬，李军. 恙虫病基础研究与诊疗进展. 右江民族医学院学报. 2021(05): 672-675+679 .

    Other cited types(3)

  • Created with Highcharts 5.0.7Amount of accessChart context menuAbstract Views, HTML Views, PDF Downloads StatisticsAbstract ViewsHTML ViewsPDF Downloads2024-052024-062024-072024-082024-092024-102024-112024-122025-012025-022025-032025-04020406080100
    Created with Highcharts 5.0.7Chart context menuAccess Class DistributionFULLTEXT: 27.5 %FULLTEXT: 27.5 %META: 71.6 %META: 71.6 %PDF: 0.8 %PDF: 0.8 %FULLTEXTMETAPDF
    Created with Highcharts 5.0.7Chart context menuAccess Area Distribution其他: 12.1 %其他: 12.1 %其他: 1.4 %其他: 1.4 %上海: 0.6 %上海: 0.6 %东莞: 0.8 %东莞: 0.8 %保定: 0.3 %保定: 0.3 %北京: 1.4 %北京: 1.4 %十堰: 0.3 %十堰: 0.3 %台北: 0.3 %台北: 0.3 %哥伦布: 0.3 %哥伦布: 0.3 %嘉兴: 0.6 %嘉兴: 0.6 %大连: 0.8 %大连: 0.8 %天津: 2.5 %天津: 2.5 %太原: 0.8 %太原: 0.8 %帕特雷: 0.8 %帕特雷: 0.8 %常州: 0.3 %常州: 0.3 %张家口: 11.5 %张家口: 11.5 %悉尼: 1.7 %悉尼: 1.7 %扬州: 0.3 %扬州: 0.3 %昆明: 2.2 %昆明: 2.2 %曲靖: 0.6 %曲靖: 0.6 %朝阳: 0.3 %朝阳: 0.3 %杭州: 1.1 %杭州: 1.1 %淄博: 0.6 %淄博: 0.6 %深圳: 0.3 %深圳: 0.3 %温州: 0.6 %温州: 0.6 %漯河: 4.2 %漯河: 4.2 %石家庄: 4.2 %石家庄: 4.2 %罗奥尔凯埃: 0.8 %罗奥尔凯埃: 0.8 %自贡: 0.3 %自贡: 0.3 %芒廷维尤: 30.6 %芒廷维尤: 30.6 %莆田: 0.8 %莆田: 0.8 %衡阳: 0.3 %衡阳: 0.3 %襄阳: 0.6 %襄阳: 0.6 %西宁: 12.9 %西宁: 12.9 %达吉斯坦共和国: 0.6 %达吉斯坦共和国: 0.6 %运城: 0.6 %运城: 0.6 %邯郸: 0.6 %邯郸: 0.6 %郑州: 0.6 %郑州: 0.6 %长沙: 0.6 %长沙: 0.6 %其他其他上海东莞保定北京十堰台北哥伦布嘉兴大连天津太原帕特雷常州张家口悉尼扬州昆明曲靖朝阳杭州淄博深圳温州漯河石家庄罗奥尔凯埃自贡芒廷维尤莆田衡阳襄阳西宁达吉斯坦共和国运城邯郸郑州长沙

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索
    Get Citation
    PDF
    XML

    Article Metrics

    Article views (2438) PDF downloads(97) Cited by(8)
    Proportional views
    Related

    Copyright © 《昆明医科大学学报》编辑部  滇ICP备00000000号-0

    Publishing: 昆明医科大学学报编辑部

    Supported by: Beijing Renhe Information Technology Co. Ltd    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return