Zhang Min Li , Shen Zhong Ming , Zhu Sha , Zhang Juan Juan . The Effect of Dezocine Analgesia on Cognitive Function of Patients after Gynecological Laparoscopic Surgery[J]. Journal of Kunming Medical University, 2016, 37(12): 107-110.
Citation: Zhang Min Li , Shen Zhong Ming , Zhu Sha , Zhang Juan Juan . The Effect of Dezocine Analgesia on Cognitive Function of Patients after Gynecological Laparoscopic Surgery[J]. Journal of Kunming Medical University, 2016, 37(12): 107-110.

The Effect of Dezocine Analgesia on Cognitive Function of Patients after Gynecological Laparoscopic Surgery

Funds:

基金: 昆明市妇幼保健院院内自选基金项目(2015-08);

  • Received Date: 2016-09-20
  • Objective To discuss the application of Mini Mental State Scale(the mini-mental state examination MMSE) test in assess the effect of dezocine analgesia therapy on the cognitive function of patients with agitation in recovery period of general anesthesia after gynecological laparoscopic surgery.Methods We observed210 cases of elective gynecologic laparoscopic surgery in our hospital from January 2015 to December 2015,ASA grade I or II.All patients were transrered to PACU(ICU) after extubation, and were divided into three groups:A,B,C group,each with 70 cases in each group.Patients with severe agitation in A group were timely given 10 mg of dezocine, patients with mild agitation in B group were given 10 mg of dezocine after a delay of 5~10 minutes,and patients without agitation in C group were not given dezocine.Then the MMSE test was performed to evaluate the cognition scores of patients in the three groups.The MMSE scores immediately, 15 minutes, 30 minutes, 60 minutes after given dezocine and 24 hours after operation were recorded.Results The statistical results showed that there were significant differences in the MMSE scores of patients immediately and at 30 minutes after given dezocine between three groups(P<0.05);and there was no significant difference in the MMSE scores of patients at60 minutes after given dezocine and 24 hours after operation between three groups(P >0.05).Conclusion Dezocine analgesia therapy has no effect on the cognitive function of patients with agitation in recovery period of general anesthesia after gynecological laparoscopic surgery.Dezocine can be safely used for analgesia and sedationtreatment for patients with agitation in recovery period of general anesthesia after gynecological laparoscopic surgery analgesia,sedation agitation.
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  • [1]周小燕,巫秀珍.麻醉与老年患者术后认知功能障碍的相关研究[J].河北医学,2013,19(6):801-804.
    [2] 郭安梅,张万江,郭素香,等.术后知识功能障碍的评判方法与评判标准[J].国际麻醉与复苏杂志,2012,33(1):46-48.
    [3]
    [3]RUDOLPH J L,SCHREIBER K A,CULLEY D J,et al.Measurement of post-operative congnitive dysfunction after cardiac suegry:A systematic review[J].Acta Anaesthesiol Scand,2010,54(6):63-77.
    [4]熊玲玲,阮霞,周伟.地佐辛超前镇痛在腹腔镜妇科手术中的应用医学临床研究[J].2011,28(9):1657-1658.
    [5]师小伟,熊源长,刘蓉.地佐辛临床镇痛的研究进展[J].医学综述,2013,19(6):1106-1107.
    [6]耿立成,李丽,冯洁.地佐辛药理及临床应用新进展[J].医学综述,2012,18(23):4029-4030.
    [7]刘清海,郎宇,王天龙,等.老年室壁瘤患者半髋置换术麻醉管理1例报告[J].北京医学,2014,(8):709-710.
    [8]张承华,麻伟青,等.青壮年择期非心脏手术后谵妄的发生率及危险因素分析[J].昆明医学院学报,2011,32(1):95-98.
    [9]赵敏,张毅,赵力,等.老年直肠癌患者轻度低温下IL-2、IL-10变化与术后早期认知功能相关性的研究[J].昆明医科大学学报,2013,34(9):96-101.
    [10]
    [10]FODALE V,SANTAMARIA L B,SCHIFILITI D,et al.Anaesthetics andpostoperative congnitive dysfunction:Pathological mechanismmimicking Alzeimer’s disease[J].Anaesthesia,2010,65(4):388-395.
    [11]魏芳,闻庆平,王春梅.右美托咪啶对老年患者术后认知功能影响的Meta分析[J].中国医科大学学报,2015,44(9):790-791.
    [12]
    [12]KRENK L,RASMUSSEN L S,KEHLET H.New insightsinto the pathophysiology of postoperativecognitive dysfunction[J].Acta Anaethesiol Scand,2010,54(8):951-956.
    [13]左蕾,李琪英.麻醉与术后认知功能障碍相关机制的研究进展[J].医学综述,2013,19(l0):1847-1848.
    [14]毕江江,王金韬,万里,等.腹腔镜胃肠手术术后认知功能障碍的危险因素分析[J].临床外科杂志,2015,23(11):855-857.
    [15]余毅,李增棋,陈昆,等.乌司他丁对心脏联合瓣膜置换术患者S100β蛋白及早期认知功能障碍的影响[J].中国现代医生,2015,53(14):75-76.
    [16]杨海慧,黄焕森,李长科.地佐辛术毕前应用对妇科腹腔镜手术患者复苏期及术后疼痛的影响[J].重庆医学,2014,43(10):1203-1205.
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