Clinical Significance of Serum Level of CA125 in Concurrent Chemoradiotherapy for High-risk Endometrial Cancer

Yang Lin Lin

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Yang Lin Lin . Clinical Significance of Serum Level of CA125 in Concurrent Chemoradiotherapy for High-risk Endometrial Cancer[J]. Journal of Kunming Medical University, 2016, 37(02).

Citation:

Yang Lin Lin . Clinical Significance of Serum Level of CA125 in Concurrent Chemoradiotherapy for High-risk Endometrial Cancer[J]. Journal of Kunming Medical University, 2016, 37(02).

Yang Lin Lin . Clinical Significance of Serum Level of CA125 in Concurrent Chemoradiotherapy for High-risk Endometrial Cancer[J]. Journal of Kunming Medical University, 2016, 37(02).

Citation:

Yang Lin Lin . Clinical Significance of Serum Level of CA125 in Concurrent Chemoradiotherapy for High-risk Endometrial Cancer[J]. Journal of Kunming Medical University, 2016, 37(02).

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Clinical Significance of Serum Level of CA125 in Concurrent Chemoradiotherapy for High-risk Endometrial Cancer

Yang Lin Lin

(Dept. of Gynecology,The Third Affiliated Hospital of Kunming Medical University,Tumor Hospital of Yunnan Province,Kunming Yunnan 650118,China)

Abstract

Abstract

［Abstract］Objective To explore the value of serum CA125 in patients with high-risk endometrial carcinoma after concomitant chemoradiotherapy（CRT）and radiotherapy（RT） alone. Methods We detected the serum CA125 levels of 21 cases of postoperative DDP+5FU concurrent chemotherapy and 22 cases of postoperative radiotherapy for high-risk endometrial cancer，before and after operation，before and after chemoradiotherapy and/or radiotherapy. Results The serum CA125 levels of patients after concurrent chemoradiotherapy were significantly lower than before and after operation（P < 0.05）. The serum CA125 levels of patients after radiotherapy were lower than before and after operation，but the difference had no statistical significance（P > 0.05）. The average follow-up was 30 months，there were 6 cases of recurrence in radiotherapy group，1 cases of recurrence in the chemoradiotherapy group. Conclusions　Detection of serum CA125 levels of patients with high-risk endometrial cancer before surgery，adjuvant therapy is helpful to postoperative. After treatment，regular detection of serum CA125 can predict the risk of recurrence of uterine endometrial carcinoma.
- ［Key words］Endometrial cancer；Chemoradiotherapy；Radiotherapy；CA125,

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