The Clinical Characteristics of Patients with Chronic Heart Failure with Preserved Ejection Fraction

［Abstract］Objective　To investigate the difference in the clinical characteristics of patients with chronic heart failure with preserved ejection fraction（HF-PEF），HF-PEF，borderline andreduced ejection fraction （HF-REF）. Methods Two hundred and twenty-two patients with chronic heart failure in our hospital between August 2013 and August 2015 were analysed retrospectively. According to the different LVEF， the patients were divided into HF-PEF group（ n＝81），HF-PEF group，borderline group（n＝71） and HF-REF group（n＝70）. Each patient received examinations of echocardiography， electrocardiogram（ECG），blood biochemistry. And the clinical data of patients were recorded and the clinical characteristics of HF-PEF，HF-PEF，borderline and HF-REF were compared. Results （1）The difference was statistically significant between HF-PEF and HF-REF in patients with age， sex， occupation ratio，smoking history，body mass index（BMI），the basic cause of coronary heart disease， hypertension，atrial fibrillation and heart function classification，systolic blood pressure，and heart rate（P＜0.05）. （2）Compared with patients with HF-REF， E/A（mitral diastolic blood flow velocity / mitral diastolic blood flow velocity），left atrial diameter， pulmonary artery diameter，LVEDD（left ventricular end diastolic diameter） were larger，and LVEF was lower，while the HF-PEF patients had a thicker ventricular septum（P < 0.05）. （3）Compared with the patients with HF-REF， the QRS interval was shorter，Atrial arrhythmia was easy to occur in patients with HF-PEF，but ventricular arrhythmia in patients with HF-REF easy to occur（ P＜0.05）;（4） Compared with HF-REF patients， the levels of serum cholesterol，triglyceride，serum creatinine，blood urea nitrogen， blood urea nitrogen，serum uric acid，C reactive protein and N- terminal brain natriuretic peptide in patients with HF-PEF were statistically different（P＜0.05）. Conclusions　In HF-PEF patients，the proportion of women，workers and so on is higher， the elderly patients are more， and the body mass index and blood pressure level is higher. Patients with history of hypertension have higher incidence of atrial fibrillation. HF-PEF patients with concentric hypertrophy have obvious diastolic dysfunction . The evaluation of cardiac function in patients with HF-PEF shows that the proportion of cardiac function grade II is higher and these patients are more prone to atrial arrhythmias.